TOR is required for endocycle progression to activate ecdysone biosynthesis. by Yuya Ohhara (3697570)

“…<p><b>(A)</b> Expression of TOR^DN in the PG causes arrest in DNA content increase at the 3rd instar larval stage. …”

Inhibition of ROCK with Y-27632 causes relaxation of rat mesenteric collecting lymphatics. by Kristine H. Kurtz (548350)

“…</i> AMP/MaxD significantly decreased with 5–50 μM Y-27632. <i>E.</i> Y-27632 (25–50 μM) significantly decreased lymphatic tone. …”

DataSheet1_Uptake of selected organic ligands by hardened cement paste: Studies on proxy ligands for the degradation of polyacrylonitrile and general considerations on the role of... by P. G. Szabo (13908240)

“…On the contrary, GTA induces a clear decrease in the surface charge above [GTA]_tot ≈ 10⁻³ M resulting in an isoelectric point at [GTA]_tot ≈ 6⋅10⁻² M. …”

Efflux activity for Hoechst33342. by Nobu Oshima (595200)

“…<p>(A) The OSK-SW480 cells included a population of cells unlabeled by 5 µg/ml of Hoechst33342 with the co-administration of 50 µM of verapamil (VM). …”

Efflux activity for Hoechst33342. by Nobu Oshima (595200)

“…<p>(A) The OSK-SW480 cells included a population of cells unlabeled by 5 µg/ml of Hoechst33342 with the co-administration of 50 µM of verapamil (VM). …”

Effect of appetite suppressants on head-weaving stereotypy in female rats. by Axl Lopez (21594203)

“…Notably, one subject (cyan dot) showed a considerable decrease in stereotypy levels on the third day, quantified after 100 minutes post-injection. …”

HAI-2 deficiency disrupts normal architecture of intestinal epithelium. by Roman Szabo (138655)

“…P values: * <0.05, **<0.01, ***<0.001. Scale bars: <b>(A-F’)</b> 75 μm, <b>(G-H’)</b> 50 μm.</p>…”

AZD8055, an mTOR inhibitor stimulates neuronal autophagy by inducing Atg4b-dependent autophagy flux in cultured neurons. by Catia C. Proenca (431486)

“…AZD8055 treatment led to a significant increase in autophagy flux observed by a decrease in p62 level. …”

Syntheses, Characterization, and the Ethylene (Co-)Polymerization Screening of 2-Benzimidazolyl-<i>N</i>-phenylquinoline-8-carboxamide Half-Titanocene Chlorides by Wen-Hua Sun (1392202)

“…According to the catalytic system of <b>C1</b>/MAO, both elevating the reaction temperature and increasing the ratio of MAO to titanium precursor enhance the productivities; however, the molecular weights of the resultant polymers obtained decrease against their higher activities. Moreover, copolymerizations of ethylene with either 1-hexene or 1-octene effectively produce copolymers with incorporated comonomers of 2.0−5.0% mol.…”

Derricin and derricidin reduce cell number and cell viability of colon cells. by Barbara F. Fonseca (703153)

“…(F) DLD-1 nuclei were decreased about 44% and 50% after derricin treatment at 30 and 50 μM concentrations, respectively. …”

DataSheet1_Design, Synthesis and Anti-Lung Cancer Evaluation of 1, 2, 3-Triazole Tethered Dihydroartemisinin-Isatin Hybrids.docx by Haodong Hou (11843693)

“…In particular, hybrids 8a,c (IC₅₀: 7.54–12.1 μM) and 9i (IC₅₀: 9.10–15.9 μM) were comparable to cisplatin (IC₅₀: 7.54–15.9 μM vs 9.38–19.7 μM) against A549 and A549/DOX, but 4.6–7.6 folds more potent than that of cisplatin (IC₅₀: 8.77–14.3 μM vs 66.9 μM) against A549/DDP cells. …”

Chloroquine (CQ) treatment blocks autophagosome–lysosome fusion and induces myopathy in the larva. by Jonathan Zirin (483506)

Data from: Viviparity does not affect the numbers and sizes of reptile offspring by Shai Meiri (394933)

Supplementary Material for: The Protective Effects of Κ-Opioid Receptor Stimulation in Hypoxic Pulmonary Hypertension Involve Inhibition of Autophagy Through the AMPK-MTOR Pathway by Zhou Y. (3218202)

“…<b><i>Results:</i></b> Inhibition of autophagy by the administration of chloroquine prevented the development of HPH in the rat model, as evidenced by significantly reduced mPAP and RVP, as well as decreased autophagy. U50,488H mimicked the effects of chloroquine, and the effects of U50,488H were blocked by nor-BNI, a selective κ-opioid receptor antagonist. …”

Overview of the comparative analysis of deconvolution model performances using synthetic spatial data in four different scenarios and six different mixture percentages. by Nuray Sogunmez Erdogan (21533872)

“…WISpR emerged as low error prone especially in blended data (Mix[50,50,0], Mix[50,40,10], Mix[50,30,20], Mix[50,20,30], Mix[50,10,40], Mix[50,0,50]). …”

Pharmacological manipulations and neuron model. by Dominique Martinez (229854)

“…<p>(<b>A</b>) Effects of bicuculline (BIC) and picrotoxin (PTX). …”

Toll signaling in the Drosophila larval fat body shifts programs of anabolic lipid metabolism and dysregulates nutrient storage by Brittany Martínez (8728753)

“…However, we observe 50% decreases in fat body transcript levels of both <i>lipin</i>, a phosphatidic acid phosphatase,<i> </i>and<i> midway, </i>the homolog of diacylglycerol acyltransferase, both of which carry out triglyceride synthesis. …”

Image_1_C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Atten... by Nirmal K. Banda (1477765)

“…Total scores for histopathology were also 50% decreased (p < 0.0005) in CIA mice treated with C2-Crry. …”

AKMT is important for invasion and egress, but not for parasite replication. by Aoife T. Heaslip (207534)

“…(C) The loss of AKMT results in a ∼90% decrease in invasion efficiency. The number of invaded parasites per field was counted in 10 fields each in 3 independent experiments. ***: P value <0.0001 (D) <i>Top</i>: Outline of A23187 induced egress assay. …”

Image_3_C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Atten... by Nirmal K. Banda (1477765)

“…Total scores for histopathology were also 50% decreased (p < 0.0005) in CIA mice treated with C2-Crry. …”