KCNQ Channels Show Conserved Ethanol Block and Function in Ethanol Behaviour by Sonia Cavaliere (116850)

“…We show that the single KCNQ channel in <em>Drosophila</em> (dKCNQ) has similar electrophysiological properties to neuronal KCNQ2/3, including conserved acute sensitivity to ethanol block, with the fly channel (IC₅₀ = 19.8 mM) being more sensitive than its mammalian ortholog (IC₅₀ = 42.1 mM). …”

Impact of local reference laboratory and external quality assurance measures on BUD control. by Marcus Beissner (139059)

“…Analysis for linear trends in proportions revealed a significant (<i>p</i><0.01) increase of patients presenting with non-ulcerative lesions from 37.0% (2007–2010) to 50.0% (2011–2012). …”

Table_1_Oleanolic Acid Mitigates 6-Hydroxydopamine Neurotoxicity by Attenuating Intracellular ROS in PC12 Cells and Striatal Microglial Activation in Rat Brains.DOCX by Zama N. P. Msibi (7292738)

Differential modulation of a transient chloride current by tyramine (TA) and octopamine (OA). by Sami H. Jezzini (650703)

“…The first step to +40 mV from the holding potential of −20 mV evokes no I_Cl-T and provides the baseline. …”

Optogenetic simulation to silence interneurons. by Kwangjun Lee (22226994)

Image_9_Absence of Wdr13 Gene Predisposes Mice to Mild Social Isolation – Chronic Stress, Leading to Depression-Like Phenotype Associated With Differential Expression of Synaptic P... by Shiladitya Mitra (685539)

Image_7_Absence of Wdr13 Gene Predisposes Mice to Mild Social Isolation – Chronic Stress, Leading to Depression-Like Phenotype Associated With Differential Expression of Synaptic P... by Shiladitya Mitra (685539)

Image_8_Absence of Wdr13 Gene Predisposes Mice to Mild Social Isolation – Chronic Stress, Leading to Depression-Like Phenotype Associated With Differential Expression of Synaptic P... by Shiladitya Mitra (685539)

Image_6_Absence of Wdr13 Gene Predisposes Mice to Mild Social Isolation – Chronic Stress, Leading to Depression-Like Phenotype Associated With Differential Expression of Synaptic P... by Shiladitya Mitra (685539)

DataSheet_1_Tuning Scorpion Toxin Selectivity: Switching From KV1.1 to KV1.3.docx by Andrei M. Gigolaev (9090713)

“…Despite several decades of research the molecular determinants of KTx selectivity are still poorly understood. Here we analyze MeKTx13-3 (Kalium ID: α-KTx 3.19) from the lesser Asian scorpion Mesobuthus eupeus, a high-affinity K_V1.1 blocker (IC₅₀ ~2 nM); it also affects K_V1.2 (IC₅₀ ~100 nM), 1.3 (~10 nM) and 1.6 (~60 nM). …”

Ellagic Acid Derivatives from <em>Terminalia chebula</em> Retz. Downregulate the Expression of Quorum Sensing Genes to Attenuate <em>Pseudomonas aeruginosa</em> PAO1 Virulence by Sajal Sarabhai (104656)

“…<em>C. elegans</em> fed on F7-treated <em>P. aeruginosa</em> showed enhanced survival with LT50 increasing from 24 to 72 h. LC-ESI-MS of F7 revealed the presence of ellagic acid derivatives responsible for anti QS activity in <em>T. chebula</em> extract.…”

CPSF6-NLS chimeras confer virus-specific infectivity defects. by Nicholas Rohlfes (20577485)

Isoform-specific Tutl overexpression differentially regulates dendrite branching in class II and III da neurons. by Mikolaj J. Sulkowski (177479)

Flow diagram for generation of ZFN mutants, and HRMA analysis. by Lingyan Xing (310457)

“…Abnormal melt curves (arrowheads) are detected at dilutions of 1∶20 mutant:wild-type DNA, but not (or very minimally) at a dilution of 1∶50. (D) Schematic diagram of foxP2 protein domains; asterisk shows the targeted region for ZFN mutagenesis; sequence above the picture is the nucleotide sequence targeted. …”

Tissular and cellular effects of simulated UV daylight on human reconstructed skin. by Claire Marionnet (244033)

“…<p>(a): DUVR spectrum was recorded with a calibrated Macam spectroradiometer. …”

Results of MC simulations of VO and agonist infusion. by Johane H. Bracamonte (12883844)

“…<p>Top panels show normalized growth in CellArea for 100 representative simulations (gray lines), with terminal values indicated by black circles; adjacent boxplots reflect the mean, CI50, and CI90 of terminal values for 1000 simulations of a) Untreated VO, c) ISO infusion, and e) AngII infusion. …”

GmmSRPN10 is secreted into the midgut lumen and is important for PF infection. by Cher-Pheng Ooi (682424)

“…(D) The knockdown of <i>GmmSRPN10</i> results in a small but significant decrease in PF midgut infection, suggesting that the expression of GmmSRPN10 is important for PF survival (each data point represents a biological replicate, with a total of >300 flies dissected scored for infection per treatment).…”

LET-60 (Ras) activation is sufficient to cause tail swelling and is required for the Dar response to infection. by Rachel McMullan (183027)

“…This decrease was not observed using <i>ras-1(gk237)</i> and <i>ras-2(ok628)</i> mutants that showed a wild-type response to infection (A). …”

Non-invasive brain stimulation demonstrates multistability of macroscopic activity in interconnected networks. by Katrina M. Kutchko (476513)

“…SW had a decreased chance of transitioning to SP.</p>…”

The Effect of Jatropha Curcas Seed Meal on Growth Performance and Internal Organs Development and Lesions in Broiler Chickens by CR Barros (12802889)

“…Treatments led to a decrease of the relative weight of testis and spleen, and to an increase in heart relative weight. …”