Evaluation of safety and immunogenicity of a group A streptococcus vaccine candidate (MJ8VAX) in a randomized clinical trial by Silvana Sekuloski (209827)

“…The level of these antibodies decreased with time during follow-up. Participants who received the vaccine also had a corresponding increase in anti-DT serum antibodies.…”

Fig 5 - by Alexandra Gaspar-Pintiliescu (17973043)

Response of a representative cell. by Taekjun Kim (302640)

“…Spike density following S1–S2 sequence was compared with spike density following S2 for each of temporal epochs of 30 ms with a shift of 5 ms. The temporal epochs with a statistically-significant decrease in spike density as determined with Mann-Whitney U-test are shown in blue bars, and significant increase in red bars, centering on corresponding analysis windows, revealing the magnitude and time course of suppressive and facilitative effects of S1 that depend on S1 position and SOA. …”

Dietary Restriction Induces Gluconeogenic Gene <i>pck-2</i> Expression via DAF-16, and <i>pck-2</i> Expression is Needed for DR-associated Healthspan Benefits. by Brian Onken (86790)

“…<p>(A) Representative wild-type animals expressing a GFP transcriptional reporter for <i>pck-2</i> (<i>pck-2</i> promoter GFP fusion, lacking <i>pck-2</i> coding sequences) under <i>ad libitum</i> (AL) or dietary restricted (DR) conditions, day 4 of life. …”

Data_Sheet_1_Loud noise-exposure changes the firing frequency of subtypes of layer 5 pyramidal neurons and Martinotti cells in the mouse auditory cortex.docx by Ingrid Nogueira (15407156)

“…When comparing individual firing properties, noise exposure differentially affected type A and B PC firing frequency in response to depolarizing current steps. Specifically, type A PCs decreased initial firing frequency in response to +200 pA steps (p = 0.020) as well as decreased steady state firing frequency (p = 0.050) while type B PCs, on the contrary, significantly increased steady state firing frequency (p = 0.048) in response to a + 150 pA step 1 week after noise exposure. …”

Development of Prolinol Containing Inhibitors of Hypoxanthine–Guanine–Xanthine Phosphoribosyltransferase: Rational Structure-Based Drug Design by Dianne T. Keough (4660351)

“…Against <i>TBr</i> in cell culture, a prodrug exhibited an EC₅₀ of 10 μM. …”

The KOR antagonist BTRX-335140 blocks U-69,593 responses in mPFC-projecting VTA dopamine neurons. by Elyssa B. Margolis (7933838)

3‑Hydroxypyridin-4(1<i>H</i>)‑one Derivatives as <i>pqs</i> Quorum Sensing Inhibitors Attenuate Virulence and Reduce Antibiotic Resistance in <i>Pseudomonas aeruginosa</i> by Zhi-Ying Miao (9388615)

“…The most potent derivative <b>16e</b> was identified as a selective inhibitor of the <i>pqs</i> system (IC₅₀ = 3.7 μM) and its related virulence factor pyocyanin (IC₅₀ = 2.7 μM). …”

The synthetic lethality of the <i>erd1</i>Δ mutation with the Neo1p-depleted <i>cfs1</i>Δ mutation is not caused by reduced levels of cytoplasmic Pi. by Mamoru Miyasaka (9187916)

“…Cells were grown and spotted, as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0236520#pone.0236520.g001" target="_blank">Fig 1B</a>, in YPGA (galactose) or YPDA (glucose) medium with either 20 mM Pi or 50 mM Pi and then incubated at 30°C for 1.5 d. …”

Novel Allosteric Inhibitors of Deoxyhypusine Synthase against Malignant Melanoma: Design, Synthesis, and Biological Evaluation by Kai-li Liu (11378101)

“…Furthermore, by western blot analysis, compound <b>8m</b> effectively activated caspase 3 and decreased the expressions of GP-100, tyrosinase, eIF5A2, MMP2, and MMP9. …”

Novel Allosteric Inhibitors of Deoxyhypusine Synthase against Malignant Melanoma: Design, Synthesis, and Biological Evaluation by Kai-li Liu (11378101)

“…Furthermore, by western blot analysis, compound <b>8m</b> effectively activated caspase 3 and decreased the expressions of GP-100, tyrosinase, eIF5A2, MMP2, and MMP9. …”

Novel Allosteric Inhibitors of Deoxyhypusine Synthase against Malignant Melanoma: Design, Synthesis, and Biological Evaluation by Kai-li Liu (11378101)

“…Furthermore, by western blot analysis, compound <b>8m</b> effectively activated caspase 3 and decreased the expressions of GP-100, tyrosinase, eIF5A2, MMP2, and MMP9. …”

Novel Allosteric Inhibitors of Deoxyhypusine Synthase against Malignant Melanoma: Design, Synthesis, and Biological Evaluation by Kai-li Liu (11378101)

“…Furthermore, by western blot analysis, compound <b>8m</b> effectively activated caspase 3 and decreased the expressions of GP-100, tyrosinase, eIF5A2, MMP2, and MMP9. …”

Management of Recurrent Bronchopleural Fistula: A Multidisciplinary Approach for A Reconstructive Challenge by Karishma Chandarana (4607131)

“…<p> </p> <p>Urgent pneumonectomy for benign disease is rare but highly morbid, with a perioperative mortality approaching 50 percent. …”

Temporal and spatial variation of potassium balance in agricultural land at national and regional levels in China by Yingxia Liu (792213)

“…<div><p>Linking potassium (K) balance to soil fertility creates a valuable indicator for sustainability assessment in agricultural land-use systems. …”

Hemodynamic parameters. by Paulina Kania-Olejnik (19797617)

“…Anteroposterior diameter increased from 36.5±5.0mm to 38.4±5.5mm (<i>p</i> = 0.05). TA contraction decreased from 7±2% in SR to 2±1% in AF (p = 0.001). …”

Tricuspid annular dimensions. by Paulina Kania-Olejnik (19797617)

“…Anteroposterior diameter increased from 36.5±5.0mm to 38.4±5.5mm (<i>p</i> = 0.05). TA contraction decreased from 7±2% in SR to 2±1% in AF (p = 0.001). …”

Regional tricuspid annular perimeter. by Paulina Kania-Olejnik (19797617)

“…Anteroposterior diameter increased from 36.5±5.0mm to 38.4±5.5mm (<i>p</i> = 0.05). TA contraction decreased from 7±2% in SR to 2±1% in AF (p = 0.001). …”

TcdA-induced Rac1 glucosylation and cytotoxicity are dynamin-dependent. by Ramyavardhanee Chandrasekaran (3394916)

“…RT-PCR confirms that siRNA treatment resulted in a decrease in Dyn-1 mRNA expression. <b>(B) Pharmacological inhibition of dynamin GTPases prevents Rac1 modification by TcdA</b>. …”

DataSheet1_Evaluation of the immune response of peripheral blood mononuclear cells cultured on Ti6Al4V-ELI polished or etched surfaces.pdf by Hugo Abreu (19815654)

“…</p>Methods<p>Ti6Al4V with extra low interstitial (ELI) content discs were treated with hydrofluoric acid followed by a controlled oxidation step in hydrogen peroxide that creates a complex surface topography with micro- and nano-texture and modifies the chemistry of the surface oxide layer. …”