VPS34 inhibition decreases intracellular levels of cholesteryl-esters, blocks cholesterol uptake and enhances lysosomal degradation of LDLR. by Marek J. Kobylarz (9292599)

GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age. by Nicole K. Polinski (10947787)

“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”

PRV-induced infertility is caused by decreased P4 level. by Bing-Qian Su (8616981)

rHSP60 decreases LPS-induced mononuclear cell proliferation. by Igor Emiliano L. Souza (18196495)

rHSP60 decreases viability of B lymphocyte cell line but not macrophage one. by Igor Emiliano L. Souza (18196495)

Decreasing neural activity in MBONs that suppress PER when activated has modest effects. by Justine Chia (5459294)

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(B)</b> Bioluminescence recordings from the different conditions as depicted in <b>(A)</b>, the arrow indicates the time CO₂ was shifted from 5% to 1% (mean ± SE, <i>n</i> = 4 biological replicates per condition, AUC for 0 mM 0.34 ± 0.007, 1.59 ± 0.004 (<i>P</i> < 0.0001), 0.5 mM 1.00 ± 0.023, 2.68 ± 0.04 (<i>P</i> < 0.0001), 1 mM 1.66 ± 0.07, 3.34 ± 0.04 (<i>P</i> < 0.0001), 3 mM 2.06 ± 0.02, 2.79 ± 0.07 (<i>P</i> < 0.0001), 5 mM 2.02 ± 0.05, 2.43 ± 0.06 (<i>P</i> < 0.002), 7 mM 1.85 ± 0.01, 1.77 ± 0.02 (<i>P</i> < 0.02) two-sided Student’s <i>t</i> test). …”

Activating cAMP synthesis decreases liberation of propionyl-CoA from cholesterol. by Kaley M. Wilburn (12060476)

LuxR G37V has decreased DNA-binding activity. by Chelsea A. Simpson (9579303)

Assessment of intratumoral CD3+ and CD8+ lymphocyte populations. by Gerik W. Tushoski-Alemán (17951809)

Prevalence and anatomic level of stenosis ≥ 50% in either limb. by O. Stivalet (6890189)

Brain and liver GCase activity are significantly decreased in heterozygous <i>GBA1</i> D409V KI mice, with varying differences in glucosphingolipid lipids in brain and liver. by Nicole K. Polinski (10947787)

“…(A-B) GCase levels as assessed by the CBE/4-MU method are significantly decreased in the het <i>GBA1</i> D409V KI mice at 5 months of age in both brain (A) and liver (B). …”

Supplementary Material for: Decreasing Attacks and Improving Quality of Life through a Systematic Management Program for Patients with Hereditary Angioedema by Nunes F.L. (10223465)

Repetitive stress induces a decrease in sound-evoked activity. by Ghattas Bisharat (20706928)

“…These mice exhibited a minimal change in noise-evoked PPy activity when comparing the first and second week of imaging (2-way ANOVA, F = 1.79, <i>p</i> = 0.11, post hoc baseline w1 50 dB: baseline w2 50 dB <i>p</i> = 1 Bonferroni corrected, nested ANOVA (mouse nested within session) F = 1.76, <i>p</i> = 0.12, mean ± SE). …”

Simulated effects of increased pCREB combined with decreased pCaMKIIα on time courses of molecular pathways and synaptic weight W after IA training. by Yili Zhang (540283)

“…The light blue area represents W less than 200% of basal level. (B) Example of dynamics of BDNF protein/mRNA (B1-2), C/EBPβ protein (B3), pCREB (B4), pCaMKIIα (B5), Sin3a binding (B6), MeCP2 binding (B7), HDAC2 binding (B8), and W (B9), with the standard parameter values in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1010239#pcbi.1010239.t001" target="_blank">Table 1</a> (black dashed) or with <i>k</i>_{<i>basalp_creb</i>} increased by ~50% and <i>k</i>_{<i>basalp_CaMKII</i>} decreased by ~50% from control combined with higher binding levels of MeCP2, Sin3a and HDAC2 (blue) to simulate IA conditioning in infant rats. …”

Cardiac-specific p38γ/δ^act overexpression decreases cardiac glycogen storage and lipid accumulation. by Ayelén M. Santamans (5487941)

Mean daily consultation counts. by Yael Rachamin (6161423)

Summary of predictors that increase (+ UC) and decrease (- UC) the dose of propofol for the three statistical models used for data analysis. by Chiara E. Hampton (16484687)

Subjects:

Exercise test characteristics for identifying stenosis ≥ 50% in any limb among the 60 limbs with normal ABIs (> 0.91). by O. Stivalet (6890189)

Flowchart of study patients evaluated for cumulative incidence of decreased GFR estimation. by Camila de Souza dos Santos (17721066)