Ether induces proteotoxic stress, leading to a decrease in Trx protein and an increase in Hsp90 clients that are joint targets of Trx and Ubx. by Orli Snir (18625811)

“…<b>(F)</b> Representative images of Acridine Orange-stained <i>yw</i> embryos for the following cases: no treatment (up left), 5-min immersion in Citrasolv solution [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002629#pbio.3002629.ref046" target="_blank">46</a>] (up right), 5-min immersion in ether liquid (bottom right), and 1.5-h exposure to ether vapor (bottom left). …”

A PPARα Promoter Variant Impairs ERR-Dependent Transactivation and Decreases Mortality after Acute Coronary Ischemia in Patients with Diabetes by Sharon Cresci (53599)

“…<em>PPARA</em> A for both ERR-α and -γ (3.1 vs.1.9-fold; P<0.05). …”

Fold changes in selected lung tissue mRNAs specific for mucin (Muc4, Muc5ac, and Muc5b) and Th2 cytokine (IL-4, IL-5, and Il-13) genes, after mice were fed (n-3) or (n-6) PUFA enri... by Jean A. Hall (289030)

Image_5_TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1.tif by Takahiko Akagi (13138338)

“…T79M is a known mutation responsible for TRAPS, whereas G87V is a TRAPS mutation that we have reported, and T90I is a variant of unknown significance. …”

Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5‑ASA–PABA–MAC and 5‑ASA–PABA–Diamine for the T... by Jiaxing Zhao (3965057)

“…Specifically, compound <b>20g</b> displayed a 3.67-fold decrease of plasma AUC_{(tofacitinib, 0–∞)} and a 9.61-fold increase of colonic AUC_{(tofacitinib, 0–12h)}, compared with tofacitinib at a molar equivalent oral dose. …”

Predictions of random forests (RF), gradient boosting machines (GBM), and neural networks (NN) trained on 12 covariates chosen using subjective feature selection. by Dennis Ochola (11626912)

Predictions of random forests (RF), gradient boosting machines (GBM), and neural networks (NN) trained on 17 covariates selected after recursive feature selection. by Dennis Ochola (11626912)

The catalase enzyme response of <i>A</i>. <i>albopictus</i> larvae decreased (1.5-fold) in response to <i>M</i>. <i>robertsii</i>-derived copper nanoparticles. by Perumal Vivekanandhan (4863484)

<i>S.</i> Typhimurium-infected mice have tissue inflammation and thrombosis, increased hematopoiesis, and decreased splenic iron. by Diane E. Brown (160264)

“…The infected mouse had 11.5-fold more TER119^med pro-erythroblasts and 5.5-fold more TER119^high erythroblasts than the mock-infected mouse. …”

Rhox5 decreases UNC5C expression. by Mayumi Sugimoto (151133)

Mutation of four arginine residues in P34 leads to a decrease in binding between P34 and L5. by Anyango D. Kamina (4034165)

3-HPA and the 10-fold diluted reuterin-containing supernatant significantly decreased the <i>S.</i> Typhimurium χ3339 population. by Rosemarie De Weirdt (320666)

NLS-tagged RIG-I stimulates immune responses and decreased viral RNA levels in HCV-infected cells. by Christopher J. Neufeldt (478659)

Decreased <i>Resf1</i> in cell lines paradoxically decreases metastatic capacity. by Megan R. Majocha (18529925)

NaSal increased the excitability of 5-HTergic neurons, but decreased that of GABAergic neurons in the DRN of the ChR2 transgenic mouse. by Yan Jin (143500)

“…(D) Sample traces (left panel) and group data (right panel, paired Student’s <i>t</i>-test) showing that NaSal suppressed the firing of GABAergic neurons evoked by laser light (1 s, 5.5 mW, 473 nm). (E) Sample recordings from a GABAergic neuron showing that NaSal decreased voltage responses to a series of hyperpolarizing currents (-10 to -60 pA, -10 pA/step, duration: 500 ms). …”

Six weeks of voluntary wheel running decreases 5-HT_2C mRNA expression in the amygdala. by Benjamin N. Greenwood (295216)

Multiple C–H Activations of Linear Alkanes by Various (η⁵‑Cyclopentadienyl)W(NO)(CH₂CMe₃)₂ Complexes by Monica V. Shree (4092343)

“…As illustrated in the accompanying diagram, thermolysis of Cp*W­(NO)­(CH₂CMe₃)₂ (Cp* = η⁵-C₅Me₅) at 80 °C in neat linear alkanes effects three successive C–H bond activations of the hydrocarbon substrates and forms Cp*W­(NO)­(H)­(η³-allyl) complexes in which the allyl ligands are derived from the alkanes. …”

Distribution of miRs with a greater than two fold-change. by Stephanie L. Samani (17896610)

Subjects:

Image_1_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Image_1_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”