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39921
The QSAR-search of effective agents towards coronaviruses applying the Monte Carlo method
Published 2021“…A collection of possible biologically active compounds, constructed using data on the above molecular features which are statistically reliable promoters of increase or decrease of the activity, is presented.…”
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39922
Dataset for: The thermodynamic basis of glucose stimulated insulin release: a model of the core mechanism.
Published 2017“…Applied to the reported glucose concentration dependent release of insulin by perifused islet preparations (4), the model predicts that the dependence of insulin release on [ADP] is strongly cooperative with a threshold of about 30 µM and a negative Hill coefficient near -5.5. …”
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39923
Inhibition of oxygen consumption by PF-4708671.
Published 2014“…(<b>B</b>) ANOVA statistical analysis of the OCR area under the curve showed that after 2.5 uM or 5 uM PF-4708671 treatment the OCR was significantly decreased (p = 2.6*10<sup>−5</sup> and 1.97*10<sup>−9</sup>, respectively; see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0107364#pone.0107364.s005" target="_blank">Table S1</a>).…”
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39924
Data_Sheet_2_Normal distribution of H3K9me3 occupancy co-mediated by histone methyltransferase BcDIM5 and histone deacetylase BcHda1 maintains stable ABA synthesis in Botrytis cine...
Published 2024“…In addition, we found that the cause of the decreased ABA production in the ΔBcdim5 and ΔBchda1 mutants was due to cluster gene repression caused by the emergence of hyper-H3K9me3 in the ABA gene cluster. …”
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39925
Data_Sheet_3_Normal distribution of H3K9me3 occupancy co-mediated by histone methyltransferase BcDIM5 and histone deacetylase BcHda1 maintains stable ABA synthesis in Botrytis cine...
Published 2024“…In addition, we found that the cause of the decreased ABA production in the ΔBcdim5 and ΔBchda1 mutants was due to cluster gene repression caused by the emergence of hyper-H3K9me3 in the ABA gene cluster. …”
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39926
Data_Sheet_1_Normal distribution of H3K9me3 occupancy co-mediated by histone methyltransferase BcDIM5 and histone deacetylase BcHda1 maintains stable ABA synthesis in Botrytis cine...
Published 2024“…In addition, we found that the cause of the decreased ABA production in the ΔBcdim5 and ΔBchda1 mutants was due to cluster gene repression caused by the emergence of hyper-H3K9me3 in the ABA gene cluster. …”
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39927
RbmB digests VPS <i>in vitro</i>.
Published 2024“…Increasing amounts of RbmB show a decrease in the aggregates and increase in free Bap1, suggesting cleavage of VPS into small fragments. …”
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39928
A prospective study of the influence of the skeleton on calcium mass transfer during hemodialysis
Published 2018“…</p><p>Results</p><p>Calcium mass transfer varied widely among patients in each study phase with a median of -89.5, -76.8 and -3 mmol using d[Ca] 1.25 mmol/L, -106, -26.8 and 29.7 mmol using d[Ca] 1.50 mmol/L, and 12.8, -14.5 and 38 mmol using d[Ca] 1.75 mmol/L during pre-PTX, early post-PTX and late post-PTX, respectively, which was significantly different among d[Ca] (p = 0.0001) and among phases (p = 0.040). …”
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39929
Metrics for GO based protein semantic similarity: a systematic evaluation-2
Published 2011“…<p><b>Copyright information:</b></p><p>Taken from "Metrics for GO based protein semantic similarity: a systematic evaluation"</p><p>http://www.biomedcentral.com/1471-2105/9/S5/S4</p><p>BMC Bioinformatics 2008;9(Suppl 5):S4-S4.…”
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39930
<i>HNF1A</i> is necessary for reprogramming and sufficient in combination with two interchangeable transcription factors.
Published 2014“…(C–E) Consistent loss of <i>AFP</i> induction with removal of <i>HNF1A</i> (blue) from reprogramming cocktails, 6TF, 5TF, and 4TF, with little or no decrease of induction due to removal of other factors. …”
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39931
Huntingtons Disease Mice Infected with <i>Toxoplasma gondii</i> Demonstrate Early Kynurenine Pathway Activation, Altered CD8+ T-Cell Responses, and Premature Mortality
Published 2016“…The kynurenine pathway may therefore represent a point of synergism between HD and <i>T</i>. <i>gondii</i> infection. …”
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39932
Data_Sheet_1_Effect of Sublethal Prenatal Endotoxaemia on Murine Placental Transport Systems and Lipid Homeostasis.PDF
Published 2021“…At the protein level, breast cancer-related protein (Bcrp) and ABC sub-family G member 1 (Abcg1) levels were decreased in the placental labyrinth zone (Lz) at GD15.5, whereas P-glycoprotein (P-gp) and Bcrp Lz-immunostaining was decreased at GD18.5. …”
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39933
SCP-induced inhibition of PVN neurons is prevented by a selective CRF-R2 antagonist.
Published 2013“…B, Antisauvagine-30, a selective CRF-R2 antagonist (30 nM), did not affect the evoked spike firing of the neuron (upper), but abolished the SCP-induced decrease in spike firing (lower). …”
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39934
Results of Influenza Vaccination: Short Follow-Up Study of a Turkish Population
Published 2021“…There were no cases of influenza, pneumonia, or hospitalization in the 2019 season; 49.3% of the participants developed a URD (n = 74). Among participants who had been vaccinated during both influenza seasons, 47.5% had had and/or developed a URD, with a higher number of cases during the 2018-2019 season. …”
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39935
Analyses of pre-mixed A/Udorn/307/1972 with immuno-AuNPs.
Published 2013“…<p>(a) Waveguide spectrum of 8×10<sup>5</sup> PFU/ml viruses that were pre-mixed with immuno-AuNPs; 10% of the immuno-AuNPs were used. …”
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39936
Expression targets for luteinizing hormone, a well described hormone involved in ovulation.
Published 2013“…The abbreviations are provided in the supplementary abbreviation list (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0059093#pone.0059093.s005" target="_blank">File S5</a>).…”
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39937
Palmitoylation inhibitors impair APP dimerization in CHO cells.
Published 2016“…<p>A. Co-immunoprecipitation assay of CHO cells expressing HA-APP<sub>Y</sub> and APP<sub>V5</sub> in presence of increasing amounts of cerulenin (Cer) (0–100 μg/ml), where 0 μg/ml represents DMSO-treatment. …”
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39938
Cells with more On pathway input have a greater shift in temporal frequency.
Published 2018“…Cells that sensitized, decreasing their firing rate during low contrast [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006560#pcbi.1006560.ref056" target="_blank">56</a>] were excluded (n = 5 cells).…”
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39939
Impact of comorbidity on renal cell carcinoma prognosis: a nationwide cohort study
Published 2021“…During the same periods, the survival rate increased from 46% to 62% among patients with a CCI score of 1–2 and from 39% to 44% for those with a CCI score of ≥3. …”
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39940
Implementation and first experiences with a multimodal mentorship curriculum for medicine-paediatrics residents
Published 2022“…</p><p></p> <p>Among resident physicians in a single training program, a mix of mentor–mentee dyads, group-based peer mentoring and a structured curriculum has shown promise in improving resident-reported satisfaction with programmatic mentorship</p> <p>While we attempted to adapt the mentorship curriculum to an online platform with the development of the SARS-CoV-2 pandemic, reported satisfaction in overall mentorship and emotional support decreased in comparison to the prior year, an important focus for future work.…”