Deformative Transition of the Menschutkin Reaction and Helical Atropisomers in a Congested Polyheterocyclic System by Yung-Yu Chang (1724704)

“…Conformational flexibility in dipyridylethene <b>9</b> is clearly shown by its complexation with BH₃ to form helical atropisomers (<i>P,P</i>/<i>M,M</i>)-<b>10</b>. The p<i>K</i>_a values of the conjugate acids of <b>1A</b> and <b>9</b> in acetonitrile were determined to be 4.65 and 5.07, respectively, which are much smaller compared to that of pyridine <b>14a</b> (p<i>K</i>_a = 12.33), implying that the basicity, nucleophilicity, and amine alkylation rates of <b>1A</b> and <b>9</b> are markedly decreased by the severe steric hindrance of the flanking phenyl rings in the polyheterocycles.…”

Deformative Transition of the Menschutkin Reaction and Helical Atropisomers in a Congested Polyheterocyclic System by Yung-Yu Chang (1724704)

“…Conformational flexibility in dipyridylethene <b>9</b> is clearly shown by its complexation with BH₃ to form helical atropisomers (<i>P,P</i>/<i>M,M</i>)-<b>10</b>. The p<i>K</i>_a values of the conjugate acids of <b>1A</b> and <b>9</b> in acetonitrile were determined to be 4.65 and 5.07, respectively, which are much smaller compared to that of pyridine <b>14a</b> (p<i>K</i>_a = 12.33), implying that the basicity, nucleophilicity, and amine alkylation rates of <b>1A</b> and <b>9</b> are markedly decreased by the severe steric hindrance of the flanking phenyl rings in the polyheterocycles.…”

Transient imbalances in the recurrent activity cause the balanced network to act like a damped oscillator. by Grant Gillary (3187080)

“…If inhibition is faster it causes a transient decrease followed by a smaller but longer increase (red). …”

Kallikrein 6 as a Serum Prognostic Marker in Patients with Aneurysmal Subarachnoid Hemorrhage by Eduardo Martínez-Morillo (132848)

“…</p> <h3>Conclusions/Significance</h3><p>Decreased serum concentrations of KLK6 are found in patients with aSAH, with the lowest levels in patients who died.…”

Neuronal overexpression of antioxidants reduces sleep, suggesting a role for ROS in sleep regulation. by Vanessa M. Hill (5508401)

“…Each data point represents average sleep in minutes/day measured across 5 days in an individual animal; data are shown as mean ± SEM. …”

Recognition of Small Polar Molecules with an Ionic Crystal of α-Keggin-Type Polyoxometalate with a Macrocation by Sayaka Uchida (115177)

“…The complexation of Keggin-type polyoxometalates [α-XW₁₂O₄₀]<i>ⁿ</i>^- (X = P, Si, B, Co), macrocation [Cr₃O(OOCH)₆(H₂O)₃]⁺, and alkali-metal ions forms ionic crystals of Na₂[Cr₃O(OOCH)₆(H₂O)₃][α-PW₁₂O₄₀]·16H₂O (<b>1a</b>), K₃[Cr₃O(OOCH)₆(H₂O)₃][α-SiW₁₂O₄₀]·16H₂O (<b>2a</b>), Rb₄[Cr₃O(OOCH)₆(H₂O)₃][α-BW₁₂O₄₀]·16H₂O (<b>3a</b>), and Cs₅[Cr₃O(OOCH)₆(H₂O)₃][α-CoW₁₂O₄₀]·7.5H₂O (<b>4a</b>). …”

Recognition of Small Polar Molecules with an Ionic Crystal of α-Keggin-Type Polyoxometalate with a Macrocation by Sayaka Uchida (115177)

“…The complexation of Keggin-type polyoxometalates [α-XW₁₂O₄₀]<i>ⁿ</i>^- (X = P, Si, B, Co), macrocation [Cr₃O(OOCH)₆(H₂O)₃]⁺, and alkali-metal ions forms ionic crystals of Na₂[Cr₃O(OOCH)₆(H₂O)₃][α-PW₁₂O₄₀]·16H₂O (<b>1a</b>), K₃[Cr₃O(OOCH)₆(H₂O)₃][α-SiW₁₂O₄₀]·16H₂O (<b>2a</b>), Rb₄[Cr₃O(OOCH)₆(H₂O)₃][α-BW₁₂O₄₀]·16H₂O (<b>3a</b>), and Cs₅[Cr₃O(OOCH)₆(H₂O)₃][α-CoW₁₂O₄₀]·7.5H₂O (<b>4a</b>). …”

Recognition of Small Polar Molecules with an Ionic Crystal of α-Keggin-Type Polyoxometalate with a Macrocation by Sayaka Uchida (115177)

“…The complexation of Keggin-type polyoxometalates [α-XW₁₂O₄₀]<i>ⁿ</i>^- (X = P, Si, B, Co), macrocation [Cr₃O(OOCH)₆(H₂O)₃]⁺, and alkali-metal ions forms ionic crystals of Na₂[Cr₃O(OOCH)₆(H₂O)₃][α-PW₁₂O₄₀]·16H₂O (<b>1a</b>), K₃[Cr₃O(OOCH)₆(H₂O)₃][α-SiW₁₂O₄₀]·16H₂O (<b>2a</b>), Rb₄[Cr₃O(OOCH)₆(H₂O)₃][α-BW₁₂O₄₀]·16H₂O (<b>3a</b>), and Cs₅[Cr₃O(OOCH)₆(H₂O)₃][α-CoW₁₂O₄₀]·7.5H₂O (<b>4a</b>). …”

Recognition of Small Polar Molecules with an Ionic Crystal of α-Keggin-Type Polyoxometalate with a Macrocation by Sayaka Uchida (115177)

“…The complexation of Keggin-type polyoxometalates [α-XW₁₂O₄₀]<i>ⁿ</i>^- (X = P, Si, B, Co), macrocation [Cr₃O(OOCH)₆(H₂O)₃]⁺, and alkali-metal ions forms ionic crystals of Na₂[Cr₃O(OOCH)₆(H₂O)₃][α-PW₁₂O₄₀]·16H₂O (<b>1a</b>), K₃[Cr₃O(OOCH)₆(H₂O)₃][α-SiW₁₂O₄₀]·16H₂O (<b>2a</b>), Rb₄[Cr₃O(OOCH)₆(H₂O)₃][α-BW₁₂O₄₀]·16H₂O (<b>3a</b>), and Cs₅[Cr₃O(OOCH)₆(H₂O)₃][α-CoW₁₂O₄₀]·7.5H₂O (<b>4a</b>). …”

Recognition of Small Polar Molecules with an Ionic Crystal of α-Keggin-Type Polyoxometalate with a Macrocation by Sayaka Uchida (115177)

“…The complexation of Keggin-type polyoxometalates [α-XW₁₂O₄₀]<i>ⁿ</i>^- (X = P, Si, B, Co), macrocation [Cr₃O(OOCH)₆(H₂O)₃]⁺, and alkali-metal ions forms ionic crystals of Na₂[Cr₃O(OOCH)₆(H₂O)₃][α-PW₁₂O₄₀]·16H₂O (<b>1a</b>), K₃[Cr₃O(OOCH)₆(H₂O)₃][α-SiW₁₂O₄₀]·16H₂O (<b>2a</b>), Rb₄[Cr₃O(OOCH)₆(H₂O)₃][α-BW₁₂O₄₀]·16H₂O (<b>3a</b>), and Cs₅[Cr₃O(OOCH)₆(H₂O)₃][α-CoW₁₂O₄₀]·7.5H₂O (<b>4a</b>). …”

Inhibition of RhoA by Rhosin blocked phosphorylation of myosin light chain and platelet shape change. by Huzoor Akbar (340517)

“…Data in the bar graphs are mean ± SE from three experiments (*p<0.001). <b>(C-D)</b> Aspirin (1 mM) treated washed human platelets containing apyrase (3 U/ml) were incubated with U46619 (0.01 μM) or thrombin (0.005 U/ml) and platelet shape change was recorded as a decrease in light transmittance using a Lumi-Aggregometer. …”

A 10-Year Trend Analysis of Heart Failure in the Less Developed Brazil by Amanda D. F. Fernandes (8618637)

“…Pearson correlation and linear-by-linear association test for trends were calculated, with a level of significance of 5%. Results: From 2008 to 2017, HF admissions decreased 62% (p = 0.004) in Paraiba and 34% (p = 0.004) in Brazil. …”

Comparing normalized infected host flux dynamics spark-lines for all four media. by Elsa W. Birch (126254)

“…(B) Expansion of a selected subset of normalized fluxes. Host cell envelope synthesis (i), and biomass accumulation (ii) decrease similarity across media. …”

Pharmacokinetics of human IgG1 and IgG2 antibodies in NHPs. by Kenneth W. Walker (6518480)

“…Clearance was not statistically different between the IgG1 antibodies at the 1 mg/kg dose, but antibody A1’s clearance was significantly lowered (<i>F</i>(7, 9) = 7.69, <i>p</i> = 0.003) at the 5 mg/kg dose with decreased mean differences of 0.18 and 0.10 mL/h/kg compared to C1 and D1, respectively.…”

Image_2_Use of Outpatient-Derived COVID-19 Convalescent Plasma in COVID-19 Patients Before Seroconversion.pdf by Oliver F. Wirz (11431399)

Image_4_Use of Outpatient-Derived COVID-19 Convalescent Plasma in COVID-19 Patients Before Seroconversion.pdf by Oliver F. Wirz (11431399)

Image_3_Use of Outpatient-Derived COVID-19 Convalescent Plasma in COVID-19 Patients Before Seroconversion.pdf by Oliver F. Wirz (11431399)

Image_1_Use of Outpatient-Derived COVID-19 Convalescent Plasma in COVID-19 Patients Before Seroconversion.pdf by Oliver F. Wirz (11431399)

Tongue coupling as a therapeutic strategy: electromyographic analysis of different training approaches by Loslene Goulart Souza (12826660)

<i>In-vivo A</i>. <i>baumannii</i> burn wound infection. by Divakara S. S. M. Uppu (705693)

“…<p>(A). Experimental plan. (B). Mice (n = 4) were treated with erythromycin (Ery, 20 mg kg^-1), QCybuAP (50 mg kg ^-1), Q<i>n</i>-prAP (50 mg kg^-1), Q<i>n</i>-prAP + Ery (50 mg kg^-1 + 20 mg kg^-1), QCybuAP + Ery (50 mg kg^-1 + 20 mg kg^-1) and colistin (5 mg kg^-1). …”