Pharmacological targeting of polyamine and hypusine biosynthesis reduces tumour activity of endometrial cancer by Hong Im Kim (4686187)

“…Spermidine is required for the hypusine-dependent activation of eukaryotic translation initiation factors 5A1 (eIF5A1) and 5A2 (eIF5A2) and connects the MYC/ODC-induced deregulation of spermidine to eIF5A1/2 protein translation, which is increased during cancer cell proliferation. …”

Mitochondrial damage is a key event in the mechanism of oncosis in skeletal muscle cells. by Chengcheng Li (2591632)

Data_Sheet_1_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.DOCX by Ai Qing Yu (9774356)

“…Decrotonylation of PHF5A K25 contributed to decreased CDK2 expression by retained intron (RI)-induced abnormal AS, thereby accelerating fibroblast senescence, and supporting a key role of PHF5A K25 decrotonylation in aging. …”

Data_Sheet_2_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.XLS by Ai Qing Yu (9774356)

“…Decrotonylation of PHF5A K25 contributed to decreased CDK2 expression by retained intron (RI)-induced abnormal AS, thereby accelerating fibroblast senescence, and supporting a key role of PHF5A K25 decrotonylation in aging. …”

Data_Sheet_3_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.XLSX by Ai Qing Yu (9774356)

“…Decrotonylation of PHF5A K25 contributed to decreased CDK2 expression by retained intron (RI)-induced abnormal AS, thereby accelerating fibroblast senescence, and supporting a key role of PHF5A K25 decrotonylation in aging. …”

WBC-thrombus interaction affects the instantaneous mean blood velocity upstream of the thrombogenic site. by He Li (176971)

Kcnk5b activity induces IP₃R-mediated Ca²⁺ release from the ER. by Xiaowen Jiang (8291814)

A new resource allocation model partitions the genome in five expression sectors. by Mónica Chagoyen (4253800)

“…<p><b>A)</b> Top. Resource allocation model (Model 1) based on three sectors in which the expression of their constituent genes increases (positive genes, blue), decreases (negative genes, red), or remains constant (invariant genes, brown) with increasing growth rate. …”

The R code that was used to graph the acid dissociation data for H₃As(V)O₄ in S4 File. by Seth H. Frisbie (7821866)

Whole genome sequencing analysis of FLC-evolved and engineered strains. by Xin Zhou (54275)

Quantifying the Contribution of Statins to the Decline in Population Mean Cholesterol by Socioeconomic Group in England 1991 - 2012: A Modelling Study by Chris Kypridemos (719751)

“…In our ‘no statins’ scenario we predicted a mean total cholesterol of 5.36 mmol/L (95% CI: 5.33-5.40) for 2011-12. …”

Steady state voltage, concentrations and electrochemical potentials for the nanopore in Fig 5a. by Liesbeth van Oeffelen (511929)

“…<p>The values shown are those in a plane through the axis of the nanopore, with <i>V</i>_<i>L</i>−<i>V</i>_<i>R</i> = 0.5 V and a surface charge density of −50mC/m². …”

TDAG-8 and OGR-1 expression in patients with TB Lymphadenitis. by Ashley M. Whittington (16510641)

Analysis of correlations between identified metabolites and steroid hormones with general characteristic data. by Saoraya Chanmuang (13242534)

Fig 1 - by Byung Chul Kang (1905025)

Protective effect of DEX on cell viability, ROS generation, and expression of apoptosis-related proteins in TNF-α-treated cells. by Byung Chul Kang (1905025)

Plot of the density profiles in the (a) stable and (b) expansion regions for the potential (5) by J B Sudharsan (557453)

“…</strong> Plot of the density profiles in the (a) stable and (b) expansion regions for the potential (<a href="http://iopscience.iop.org/0953-4075/46/15/155302/article#jpb466473eqn05" target="_blank">5</a>).…”

Pim1 inhibition results in a reduced visual response at 5 dpf. by Jun Yin (94374)

“…Pim1 inhibitors were dissolved in 0.1% DMSO at all concentrations except the 100 µM concentration which was dissolved in 1% DMSO. (B) The ERG a-wave and b-wave are significantly decreased in 100 µM Pim1 inhibitor 2 treated fish. …”

Effects of vidarabine, V2E, V3E and V5E on AC activity in the heart of WT and AC5KO mice. by Kenji Suita (750993)

“…<p>(A) Vidarabine (Vida), V2E, V3E and V5E similarly and significantly decreased ISO (50 µmol/L)-stimulated AC activity in the WT heart in a dose-dependent manner. …”

PM2.5 associates with blood pressure: a Mendelian randomization analysis by Minghui Bao (767132)

“…<p>The relationship between fine particulate matter (PM2.5) and blood pressure (BP) is a controversial issue. …”