Comparison of the Simulated Activities of PI3K, Membrane-Bound PTEN, and the Resulting Behavior of PIP₃ (Composite Screenshot) by Martin Meier-Schellersheim (63389)

“…<p>Stimulation of a cell in a 2:1 cAMP gradient (mean concentration 500 nmol) leads to a rapid 3-fold increase in the membrane proximal activity of PI3K (green) and to a loss of membrane-bound PTEN (blue; tracked as GFP-PTEN in real cells). …”

Effects of adenosine receptor-specific antagonists on responses to hypoxia at E9.5 and E12.5. by Daniela L. Buscariollo (140729)

“…At both ages, heart rates were not affected by SCH-58261 treatment (A and B). In contrast, at both ages DPCPX elevated heart rates above vehicle levels in normoxic conditions and inhibited hypoxia-mediated heart rate decrease below baseline (A and B). …”

Transmembrane signaling in cell-derived plasma membrane vesicles. by Luigino Grasso (208932)

“…(D) The FRET signal increases with the concentration of agonist APEC added to the bulk solution (concentrations indicated above the bars in nM). (E) A dose-dependent increase of the FRET yields <i>EC₅₀</i> = 100±11 nM; shown are averages and standard deviations of the mean of nine titration experiments each performed on different, individual vesicles.…”

Effect of selected compounds on the induction of the luciferase signal at the CMV-luc construct in KG-1 cells. by Dante Rotili (462382)

Effect of enzymatic complex in the diet of pirarucu, Arapaima gigas juveniles by Julliana de Castro LIMA (12678327)

“…A decrease in the endogenous enzymatic activity (protease, lipase and amylase) suggested an improved efficacy of the digestive process. …”

Developing Updateable Habitat Models for Endangered Stephens’ Kangaroo Rats Using Satellite ImageryPhase I - Rangewide Habitat Model by Heather Rusigian-Romsos (6093715)

Mechanisms Involved in the Functional Divergence of Duplicated GroEL Chaperonins in <em>Myxococcus xanthus</em> DK1622 by Yan Wang (15435)

Enhancing the number of human otic sensory cells by Notch inhibition. by Hanae Lahlou (5394905)

“…(D) The decrease of Notch pathway components after DBZ treatment was accompanied with a significant upregulation of two otic sensory markers (<i>ATOH1</i>, <i>MYO7A</i>) transcripts. …”

Blockade of β₃AR completely restores attenuated HPV in IH rats. by Hisashi Nagai (650547)

“…The tungsten wire in the lower right corner of each image is a reference wire with a diameter of 50 μm. (B, C) Relationship between vessel size and the extent of the pulmonary vasoconstriction (% decrease in vessel diameter) induced in response to acute hypoxia in the N and IH rats treated with or without SR59230A. …”

Effects on global translation and lambda light chain synthesis. by Yijiang Shi (548692)

Analysis of NIST Monoclonal Antibody Reference Material Glycosylation Using the LC–MS/MS-Based Glycoproteomic Approach by Jingfu Zhao (3113421)

“…Glycosylation is an essential critical quality attribute (CQA) due to the influence that glycoforms have on the safety, efficacy, and pharmacokinetics/pharmacodynamics (PK/PD) of biotherapeutics. Here, we applied an LC–MS/MS-based glycoproteomics approach to characterize Fc glycans of an NISTmAb reference material (RM) 8671 (sample B) and a β-1,4-galactosidase-treated NISTmAb (sample A). …”

Depressive symptoms are associated with blunted reward learning in social contexts by Lou Safra (553574)

“…<div><p>Depression is characterized by a marked decrease in social interactions and blunted sensitivity to rewards. …”

Functional Lung Imaging during HFV in Preterm Rabbits by Jordan Thurgood (123527)

“…Whilst ventilated at fixed pressures, each animal was ventilated at frequencies of 1, 3, 5 and 10 Hz. A 50% decrease in delivered tidal volume was measured at 10 Hz compared to 1 Hz, yet at the higher frequency a 500% increase in minute activity was measured. …”

Microstructure and Wear Resistance of ZrC-ZrB2 /Ni Composite Coatings Prepared by Plasma Transferred Arc Cladding by Tian-guo Guan (6675545)

The effect of wool hydrolysates on squamous cell carcinoma cells <i>in vitro</i>. Possible implications for cancer treatment by Tatsiana Damps (4405174)

Peak calcium induced by somatic BAP decays with distance in both experiments and model simulation. by David C. Sterratt (158383)

“…<p><b>A</b>, Two-photon compressed z-stack morphology of CA1 pyramidal neuron. …”

Arterial contractility 18 hours after CASP. by Stefan Felix Ehrentraut (136865)

“…In WT mice sham surgery led to a 17% decrease of vascular contractility, compared to 45% after CASP-treatment. …”

Average player As’ transfers across rounds and resulting earnings. by Christoph Eisenegger (430948)

“…Player As increase their transfers over the 20 rounds when paired with a prosocial player B and decrease their transfers while interacting with a selfish player B. …”

The presynaptic changes in the inhibitory synaptic currents in the neocortex evaluated by PPR. by Ulyana Lalo (506296)

“…(A–C) Graphs show the representative IPSCs (average of 25 traces) evoked with a 50 ms interval in control and during application of 10 µM TFLLR. …”

DataSheet1_Passive evaporative coolers for postharvest storage of fruit and vegetables: Where to best deploy them and how well do they perform.pdf by Thijs Defraeye (9434204)

“…For these fruits, the gain in postharvest life using passive cooling is roughly 2–15 days for temperate climates with an ambient temperature of 20°C and a humidity of 50%. We present geographical maps of India, Nigeria, and the entire world at a 30 km resolution that answer how much evaporative cooling can maximally decrease the produce temperature and extend postharvest life for banana fruit. …”