Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

Data_Sheet_1_Coenzyme A-Dependent Tricarboxylic Acid Cycle Enzymes Are Decreased in Alzheimer’s Disease Consistent With Cerebral Pantothenate Deficiency.PDF by Crystal Sang (12856397)

Risk assessment for hospital admission in patients with COPD; a multi-centre UK prospective observational study by Jilles M. Fermont (3746068)

“…In total, 291 of 714 individuals experienced 762 hospitalised AECOPD during five-year follow up. Poorer performance of SPPB was associated with both higher rate (IRR 1.08 per 1 point decrease, 95% CI 1.01 to 1.14) and increased length of stay (IRR 1.18 per 1 point decrease, 95% CI 1.10 to 1.27) for hospitalised AECOPD. …”

Increases and decreases in resources. by Guangliang Li (194029)

All data points from Fig 5. by Sara Hijazi (21656615)

“…Specifically, we observed that demyelination caused an impairment in the ability of PV interneurons to sustain high-frequency firing associated with a substantial decrease in Kv3-specific currents. …”

Inadequate riparian zone use directly decreases water quality of a low-order urban stream in southern Brazil by Enzo Luigi Crisigiovanni (8709570)

5-HT supplementation inhibits mitophagy. by Li Gao (131516)

Data_Sheet_5_Chronic Neurobehavioral Impairments and Decreased Hippocampal Expression of Genes Important for Brain Glucose Utilization in a Mouse Model of Mild TBI.xlsx by Linda M. Huynh (9395591)

Effect of 5-HT depletion via pCPA on incentive. by Yukiko Hori (299784)

Subjects:

Presentation_5_Regulatory B Cells Are Decreased and Impaired in Their Function in Peripheral Maternal Blood in Pre-term Birth.PPTX by Mandy Busse (211026)

“…Interferences in the fine-tuned balance of the maternal immune system have been pointed to as one possible cause of PTB. Regulatory B cells (Breg) are part of the adaptive immune response, and recent data suggest that they may contribute to a healthy pregnancy by their regulatory/suppressive function.…”

No discernible effect of high-dose 5-HT_2AR blockade on error rates in the reward-size task. by Yukiko Hori (299784)

Subjects:

Higher reward decreases time-point variability dynamically throughout the trial. by Zvi N. Roth (9611598)

Genotype frequencies of the polymorphisms <i>rs1799971</i> (OPRM1), <i>rs6296</i> (5-HT_1A) and the triallelic 5-HTT for the whole group, as well as fibromyalgia (FM) pat... by Jeanette Tour (10790855)

Subjects:

Table 1_Effect of decreased suspended sediment content on chlorophyll-a in Dongting Lake, China.docx by Le Zhang (88249)

“…<p>Global damming of rivers strongly impacts the transport and characteristic of sediment, resulting in a significant reduction in the suspended sediment content (SSC) flowing into the downstream. …”

Table_1_Trait sensitivity to negative feedback in rats is associated with increased expression of serotonin 5-HT2A receptors in the ventral hippocampus.DOCX by Paulina Surowka (14590340)

“…The results demonstrated that trait sensitivity to negative feedback is associated with increased mRNA expression of the 5-HT2A receptors in the rat ventral hippocampus (vHipp). …”

Image5_The G protein biased serotonin 5-HT2A receptor agonist lisuride exerts anti-depressant drug-like activities in mice.JPEG by Vladimir M. Pogorelov (133492)

“…Despite these benefits, the hallucinogenic actions of these drugs at the serotonin 2A receptor (5-HT2AR) limit their clinical use in diverse settings. …”

Table_1_A phased intervention bundle to decrease the mortality of patients with extracorporeal membrane oxygenation in intensive care unit.pdf by Yajun Jing (11711139)

“…In multivariable analysis, even after excluding the confounding factors, such as age, APECHII score, pre-ECMO lactate, and incidence of CRRT during ECMO, the intervention bundle still can decrease the mortality independently, which also remained true in the statistical analysis of V-V and V-A ECMO separately. …”

Matrix crosslinking decreases cell migration persistence. by Michael Pamonag (12295175)

The influence of 5-HT on MSQ43 cells. by Li Gao (131516)

As the number of infections <i>I</i> in a given county increases, the variance in exponential growth rate, Var(Δ<i>I</i>/<i>I</i>), decreases as . by Calvin Pozderac (10451496)