Sphingosine Kinase 2 Inhibitors: Rigid Aliphatic Tail Derivatives Deliver Potent and Selective Analogues by Srinath Pashikanti (2638048)

“…Sphingosine 1-phosphate (S1P) is a pleiotropic signaling molecule that interacts with five native G-protein coupled receptors (S1P1–5) to regulate cell growth, survival, and proliferation. …”

Sphingosine Kinase 2 Inhibitors: Rigid Aliphatic Tail Derivatives Deliver Potent and Selective Analogues by Srinath Pashikanti (2638048)

“…Sphingosine 1-phosphate (S1P) is a pleiotropic signaling molecule that interacts with five native G-protein coupled receptors (S1P1–5) to regulate cell growth, survival, and proliferation. …”

Sphingosine Kinase 2 Inhibitors: Rigid Aliphatic Tail Derivatives Deliver Potent and Selective Analogues by Srinath Pashikanti (2638048)

“…Sphingosine 1-phosphate (S1P) is a pleiotropic signaling molecule that interacts with five native G-protein coupled receptors (S1P1–5) to regulate cell growth, survival, and proliferation. …”

Sphingosine Kinase 2 Inhibitors: Rigid Aliphatic Tail Derivatives Deliver Potent and Selective Analogues by Srinath Pashikanti (2638048)

“…Sphingosine 1-phosphate (S1P) is a pleiotropic signaling molecule that interacts with five native G-protein coupled receptors (S1P1–5) to regulate cell growth, survival, and proliferation. …”

Sphingosine Kinase 2 Inhibitors: Rigid Aliphatic Tail Derivatives Deliver Potent and Selective Analogues by Srinath Pashikanti (2638048)

“…Sphingosine 1-phosphate (S1P) is a pleiotropic signaling molecule that interacts with five native G-protein coupled receptors (S1P1–5) to regulate cell growth, survival, and proliferation. …”

Sphingosine Kinase 2 Inhibitors: Rigid Aliphatic Tail Derivatives Deliver Potent and Selective Analogues by Srinath Pashikanti (2638048)

“…Sphingosine 1-phosphate (S1P) is a pleiotropic signaling molecule that interacts with five native G-protein coupled receptors (S1P1–5) to regulate cell growth, survival, and proliferation. …”

Sphingosine Kinase 2 Inhibitors: Rigid Aliphatic Tail Derivatives Deliver Potent and Selective Analogues by Srinath Pashikanti (2638048)

“…Sphingosine 1-phosphate (S1P) is a pleiotropic signaling molecule that interacts with five native G-protein coupled receptors (S1P1–5) to regulate cell growth, survival, and proliferation. …”

Sphingosine Kinase 2 Inhibitors: Rigid Aliphatic Tail Derivatives Deliver Potent and Selective Analogues by Srinath Pashikanti (2638048)

“…Sphingosine 1-phosphate (S1P) is a pleiotropic signaling molecule that interacts with five native G-protein coupled receptors (S1P1–5) to regulate cell growth, survival, and proliferation. …”

Data_Sheet_5_Canopy Nitrogen Addition and Soil Warming Affect Conifer Seedlings’ Phenology but Have Limited Impact on Growth and Soil N Mineralization in Boreal Forests of Eastern... by Charles Marty (6585563)

DataSheet5_First-Line ICI Monotherapies for Advanced Non-small-cell Lung Cancer Patients With PD-L1 of at Least 50%: A Cost-Effectiveness Analysis.docx by Qiao Liu (346535)

Table_5_Endothelial Immunity Trained by Coronavirus Infections, DAMP Stimulations and Regulated by Anti-Oxidant NRF2 May Contribute to Inflammations, Myelopoiesis, COVID-19 Cytokin... by Ying Shao (200846)

“…<p>To characterize transcriptomic changes in endothelial cells (ECs) infected by coronaviruses, and stimulated by DAMPs, the expressions of 1311 innate immune regulatomic genes (IGs) were examined in 28 EC microarray datasets with 7 monocyte datasets as controls. We made the following findings: The majority of IGs are upregulated in the first 12 hours post-infection (PI), and maintained until 48 hours PI in human microvascular EC infected by middle east respiratory syndrome-coronavirus (MERS-CoV) (an EC model for COVID-19). …”

Image 5_ATP/P2X7 receptor signal aggravates ischemic stroke injury by activating Th17 cells via STAT3/IL-21 pathway.tif by Wenying Liu (781302)

Image_5_Sub-okra leaf shape conferred via chromosomal introgression from Gossypium barbadense L. improves photosynthetic productivity in short-season cotton (Gossypium hirsutum L.)... by Hui Jiang (102809)

“…Although the biomass of lines with sub-okra leaf shape was less than that of lines with normal leaves, the average first harvest yield and total yield of lines with the sub-okra leaf shape increased by 6.36% and 5.72%, respectively, compared with those with normal leaves. …”

Table_5_Brain Oscillatory and Hemodynamic Activity in a Bimanual Coordination Task Following Transcranial Alternating Current Stimulation (tACS): A Combined EEG-fNIRS Study.DOCX by Alisa Berger (5113163)

Role of <i>phoPQ</i> in indole mediated down-regulation of virulence. by Nandita Kohli (2049115)

“…(B) Invasion in HeLa epithelial cell line with <i>Salmonella</i> WT and Δ<i>phoPQ</i> strain treated with or without 1mM indole. A MOI of 100:1 was used and the data shown is the indole-treated <i>Salmonella</i> invasion normalized to the control of the respective strain. * denotes statistical significance with respect to the solvent control at <i>p</i> < 0.05 using the Student’s <i>t</i>-test. …”

Table_1_Effects of a low-sodium diet in patients with idiopathic hyperaldosteronism: a randomized controlled trial.docx by Lihua Zhou (478525)

“…</p>Methods<p>Fifty IHA patients were evenly randomized into two groups and provided, after a 7-day run-in period (100 mmol/d sodium), either a low-sodium diet (50 mmol/d sodium) or a normal sodium diet (100 mmol/d sodium) for an additional 7 days. …”

Table_5_Root-knot nematode infections and soil characteristics significantly affected microbial community composition and assembly of tobacco soil microbiota: a large-scale compari... by Yi Cao (229829)

Modal analysis showing the loci of eigenvalues of fixed point with the change of γ; <i>P</i>_<i>m</i> = 0.5 <i>and M</i> = 1.0 are fixed. by Jinpeng Ma (3342755)

“…<p>We can find that with decrease of γ from γ = 2.0 to γ = −0.5 with Δγ = −0.1, a pair of leading characteristic values (λ₁ and λ₂) comes across the imaginary axis from the left (stable region) to right (unstable region) at γ = −0.0151, indicating that the fixed point becomes unstable due to a super-critical Hopf bifurcation. …”

Table_5_Relationship between serum uric acid and estimated glomerular filtration rate in adolescents aged 12-19 years with different body mass indices: a cross-sectional study.xls by Qiuwei Tian (16653129)

presentation1_Uncovering the Pharmacological Mechanism of 2-Dodecyl-6-Methoxycyclohexa-2,5 -Diene-1,4-Dione Against Lung Cancer Based on Network Pharmacology and Experimental Evalu... by Lihui Wang (437861)

“…<p>Background: 2-Dodecyl-6-Methoxycyclohexa-2, 5-Diene-1,4-Dione (DMDD) was purified from the roots of Averrhoa carambola L. …”