Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous Toxicity by Jinxin Che (791250)

Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous Toxicity by Jinxin Che (791250)

Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous Toxicity by Jinxin Che (791250)

nanoDSF apparent melting points. by Aleksi Sutinen (10039145)

Subjects:

Average self-reported physical health ratings before or during the COVID-19 pandemic among individuals who engaged during the pandemic in more than 3 (A), 4 (B), or 5 (C) positive... by Elie Mulhem (22537863)

Proviral load in blood was decreased in HTLV-1 infected CD133+ Hu-mice when vCTCF-BS was deleted. by Ancy Joseph (5634794)

Excel file of Raw Data for Figures 2–5. by Daniel R. Ambruso (12042605)

Data_Sheet_5_Decreased default mode network functional connectivity with visual processing regions as potential biomarkers for delayed neurocognitive recovery: A resting-state fMRI study and machine-learning analysis.ZIP by Zhaoshun Jiang (7478243)

“…The algorithm performance was evaluated by a permutation test.</p>Results<p>We found significantly decreased DMN connectivity with the brain regions involved in visual processing in DNR patients than in non-DNR patients. …”

VPS34 inhibition decreases intracellular levels of cholesteryl-esters, blocks cholesterol uptake and enhances lysosomal degradation of LDLR. by Marek J. Kobylarz (9292599)

ANOM analysis of evaluated criteria K1–K5. by Roman Vavrek (13200141)

“…The presented research works with five criteria, identified by the Institute for Economic and Social Reforms, and aims to quantify the agreement of the results of the assessment of the financial health of territorial self-government entities in 2020 using the TOPSIS technique with a gradually decreasing number of criteria. …”

Validation of primary screen hits reveals compounds that recapitulate increased spheroid size (swell) or decreased MUC5AC in the lumen. by Pranjali Beri (14945400)

“…Compounds that appeared to cause toxicity were identified by observing a significant decrease in spheroid counts in the swell readout or a significant decrease in the total nuclear intensity of the MUC5AC ratio readout. …”

Fig 5 - by Lingru Ruan (18995544)

Mononucleation of the intestine causes an X chromosome specific decrease in expression levels. by Lotte M. van Rijnberk (3716362)

Nimodipine does not affect Aβ levels in cortex or hippocampus. by Katherine R. Sadleir (12035242)

TREM1 inhibition decreases HIV mediated inflammatory cytokine production. by Jinhee Hyun (6900683)

Ether Cleavage Decreases the Ion Exchange Capacity of Anion Exchange Membranes by Shakkira Erimban (6882539)

Ether Cleavage Decreases the Ion Exchange Capacity of Anion Exchange Membranes by Shakkira Erimban (6882539)

Values for the calculation of the time-dependent drug concentrations in the system based on observed data found and derived from a variety of sources. by J. Roadnight Sheehan (20141887)

Efficacy end points. by Youngmin Ko (3333819)

Subjects:

<i>IXR1</i> deletion restored the decreased expression of <i>CLB1</i> caused by <i>PUF5</i> deletion. by Megumi Sato (4116994)