A Novel Selective Inhibitor of Delta-5 Desaturase Lowers Insulin Resistance and Reduces Body Weight in Diet-Induced Obese C57BL/6J Mice by Hiroaki Yashiro (2231686)

“…Here, we demonstrate reduced insulin resistance and the anti-obesity effect of a D5D selective inhibitor (compound-326), an orally active small-molecule, in a high-fat diet-induced obese (DIO) mouse model. …”

The synchronous activity of SGN fiber populations is disrupted and their response to sound is decreased with increasing levels of <i>L</i>_<i>u</i> heterogeneity. by Maral Budak (6680351)

Decreasing HIV viral loads across subdistricts in KwaZulu-Natal province, South Africa, between 2018 and 2022. by Lilishia Gounder (15240167)

Subjects:

EGCG treatment decreases TTR amyloid deposition in the gastrointestinal tract of old hTTR V30M mice. by Nelson Ferreira (188837)

Decrease in salivary TTV titer (log₁₀ titer/ml) in individuals positive for SARS-CoV-2 as a function of time from symptom onset. by Maria C. Mendes-Correa (11326465)

V-ATPase inhibition by archazolid increases the adhesion of MDA-MB-231 cells onto HUVECs and decreases their transendothelial migration. by Betty Luong (5738027)

ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of γ-secretase activity-5 by Rodrigo A Fuentealba (77901)

“…<p><b>Copyright information:</b></p><p>Taken from "ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of γ-secretase activity"</p><p>http://www.molecularneurodegeneration.com/content/2/1/14</p><p>Molecular Neurodegeneration 2007;2():14-14.…”

Delphinidin alters VEGF-A splicing to increase VEGF-A₁₆₅b and decrease total VEGF-A expression. by Megan Stevens (3964886)

“…<p><b>A)</b> Treatment of podocytes with delphinidin chloride (10 μg/ml) under normal glucose (NG; 5 mM glucose + 25 mM mannitol) and high glucose (HG; 30 mM glucose, 1 ng/ml TNFα, 1 ng/ml IL-6, and 100 nM insulin) for 48 hrs increased the protein expression of VEGF-A₁₆₅b relative to total VEGF-A₁₆₅ (quantified in <b>B</b>; *p<0.05 vs NG, †p<0.05 vs HG; n = 3 biological repeats; One-way ANOVA with Bonferroni post-hoc test for comparison between pairs; <b>A</b>—the same blot was first probed with VEGF-A₁₆₅b before stripping and reprobing with panVEGF-A). …”

Top 5 VADER words by TF-IDF before, during, and after Hurricane Dorian for each region. by Krishna Bathina (12883820)

Top 5 VADER words by normalized TF-IDF scores before, during, and after each hurricane. by Krishna Bathina (12883820)

Supplementary Material for: Tropomyosin-Related Kinase Receptor and Neurotrophin Expression in Cutaneous Melanoma Is Associated with a Poor Prognosis and Decreased Survival by Antunes L.C.M. (6683354)

SARS-CoV-2 induced lung inflammation is increased with IL-10 blockade and decreased with IFNγ blockade. by Christine E. Nelson (18946410)

Position of viscous fingering at 0.5s. by Yu-Ting Wu (2057263)

Antagonizing BMP type I receptors decreases cell growth, proliferation, and clonogenicity of lung cancer cell lines. by Elaine Langenfeld (402034)

“…<p>(<b>A</b>) A549 and H1299 cells cultured in DMEM 5% FCS were treated with DMSO, 10 µM Dorsomorphin, 1 µM DMH1, 1 µM DMH2, or 1 µM LDN for 7 days and cell counts performed. …”

The SO-coupling-energy function <em>H_s</em> of δ₁ and δ₋₁ with η = 0.0096 and κ = 2.0 by Shu-Wei Song (557396)

A Point Mutation in a lincRNA Upstream of <i>GDNF</i> Is Associated to a Canine Insensitivity to Pain: A Spontaneous Model for Human Sensory Neuropathies by Jocelyn Plassais (564630)

“…Clinical signs appear in young puppies and consist of acral analgesia, with or without sudden intense licking, biting and severe self-mutilation of the feet, whereas proprioception, motor abilities and spinal reflexes remain intact. Through a Genome Wide Association Study (GWAS) with 24 affected and 30 unaffected sporting dogs using the Canine HD 170K SNP array (Illumina), we identified a 1.8 Mb homozygous locus on canine chromosome 4 (adj. p-val = 2.5x10^-6). …”

Image3_The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis.TIF by Sandra Torres (3361256)

Image2_The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis.JPEG by Sandra Torres (3361256)

Image4_The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis.TIF by Sandra Torres (3361256)

Image1_The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis.TIF by Sandra Torres (3361256)