Image_4_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…In vitro, the accumulation in the supernatants of the pro-angiogenic factors EMMPRIN, VEGF and MMP-9 was increased by co-culturing the HT1080 fibroblasts and the U937 monocytes, while the accumulation of the anti-angiogenic factor thrombospondin-1 (Tsp-1) and the expression levels of miR-146a-5p were reduced. Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Image_2_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…In vitro, the accumulation in the supernatants of the pro-angiogenic factors EMMPRIN, VEGF and MMP-9 was increased by co-culturing the HT1080 fibroblasts and the U937 monocytes, while the accumulation of the anti-angiogenic factor thrombospondin-1 (Tsp-1) and the expression levels of miR-146a-5p were reduced. Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Image_1_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…In vitro, the accumulation in the supernatants of the pro-angiogenic factors EMMPRIN, VEGF and MMP-9 was increased by co-culturing the HT1080 fibroblasts and the U937 monocytes, while the accumulation of the anti-angiogenic factor thrombospondin-1 (Tsp-1) and the expression levels of miR-146a-5p were reduced. Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

The 5’SS motif decreases mRNA stability and promotes nuclear retention. by Eliza S. Lee (715538)

“…Note that the relative level of <i>c-ftz-Δi-V5-His</i> decreases over the first 60 min until 40–50% of the mRNA remains, after which point the ratio is stable. …”

FLIM-FRET measurements with KIRIN1 sensor detects relative changes in intracellular K⁺. by Xiaowen Jiang (8291814)

“…For cell patch clamping and FLIM measurements, each data point represents 1 cell (A, B, C). For fish embryo FLIM imaging, we measured 2 or 3 locations in each tissue of 1 fin bud per embryo. …”

Juvenile demyelination leads to a decrease in axonal complexity of PFC PV interneurons. by Sara Hijazi (21656615)

“…The number of branch points in PV interneuron axons from cuprizone-treated mice was significantly decreased compared to control mice (<i>t test; n = 10/9 cells per group, *p < 0.05</i>). …”

Homozygous deletion of <i>ERG251</i> leads to the decreased ergosterol accumulation in the absence of FLC and decreased production of toxic dienol in the presence of FLC. by Xin Zhou (54275)

Acute myocardial infarction changes bone marrow cell composition and decreases endothelial differentiation capability. by Ming-Yao Chang (700415)

“…<p><b>(A)</b> CD14 positive cells increased at day 1 post-MI while the CD16 positive cell decreased at day 4 and day 7 after infarction in <b>B</b> with n ≥3 per groups. …”

Ludmila Belayev 12-point scoring between groups. by Guangxiao Ni (19713106)

Subjects:

A genetic variant in human FIRE is associated with a decreased interferon response in myeloid cells. by Anaïs Assouvie (9600529)

Supplementary Material for: Intestinal Vascular Endothelial Growth Factor Is Decreased in Necrotizing Enterocolitis by Sabnis A. (4149406)

SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue by Dorota Kmiec (5646374)

“…Here, we show that the Nef protein of the highly divergent SIVcol lineage infecting mantled guerezas (<i>Colobus guereza</i>) is a potent antagonist of SERINC5, although it lacks the CD4, CD3 and CD28 down-modulation activities exerted by other primate lentiviral Nefs. …”

DataSheet_1_Complement inhibition can decrease the haemostatic response in a microvascular bleeding model at multiple levels.xlsx by Murielle Golomingi (13239774)

Kcnk5b enhanced depolarization is required for enhanced fin bud growth. by Xiaowen Jiang (8291814)

Image_1_miR-144-5p and miR-451a Inhibit the Growth of Cholangiocarcinoma Cells Through Decreasing the Expression of ST8SIA4.tif by Wan Fu (3681799)

“…This study aimed to investigate the action mechanism of miR-144-5p and miR-451a in cholangiocarcinoma. We found that miR-144-5p and miR-451a were significantly decreased in cholangiocarcinoma patient samples compared to the adjacent normal bile duct samples. …”

Image_4_miR-144-5p and miR-451a Inhibit the Growth of Cholangiocarcinoma Cells Through Decreasing the Expression of ST8SIA4.tif by Wan Fu (3681799)

“…This study aimed to investigate the action mechanism of miR-144-5p and miR-451a in cholangiocarcinoma. We found that miR-144-5p and miR-451a were significantly decreased in cholangiocarcinoma patient samples compared to the adjacent normal bile duct samples. …”

Image_3_miR-144-5p and miR-451a Inhibit the Growth of Cholangiocarcinoma Cells Through Decreasing the Expression of ST8SIA4.tif by Wan Fu (3681799)

“…This study aimed to investigate the action mechanism of miR-144-5p and miR-451a in cholangiocarcinoma. We found that miR-144-5p and miR-451a were significantly decreased in cholangiocarcinoma patient samples compared to the adjacent normal bile duct samples. …”

Image_2_miR-144-5p and miR-451a Inhibit the Growth of Cholangiocarcinoma Cells Through Decreasing the Expression of ST8SIA4.tif by Wan Fu (3681799)

“…This study aimed to investigate the action mechanism of miR-144-5p and miR-451a in cholangiocarcinoma. We found that miR-144-5p and miR-451a were significantly decreased in cholangiocarcinoma patient samples compared to the adjacent normal bile duct samples. …”

Four-fold decrease in [H⁺]_e shifted GLT-1a E_rev by −18 mV at both low and high glutamate concentrations. by Anatoli Y. Kabakov (729047)

“…Arrows show GLT-1a E_rev shifts. <b>(C)</b> Average GLT-1 E_rev shifts at 37.5 μM and 600 μM are approximately equal when [H⁺]_e was decreased from 40 to 10 nM.…”

Four-fold decrease in [K⁺]_e shifted GLT-1a E_rev by +22 mV at both low and high glutamate concentrations. by Anatoli Y. Kabakov (729047)

“…Arrows show GLT-1a E_rev shifts. <b>(C)</b> Average GLT-1 E_rev shifts at 37.5 μM and 600 μM are approximately equal when [K⁺]_e was decreased from 44 to 11 mM.…”