Image_2_Long-term peritoneal dialysate exposure modulates expression of membrane complement regulators in human peritoneal mesothelial cells.TIF by Kazuma Kobayashi (817168)

“…Analyzing Met-5A cells, we observed that expressions of the three CRegs were increased by glucose and lactic acid in a concentration-dependent manner, but conversely that expressions of CRegs were decreased by lower pH stimulation. …”

Image_1_Long-term peritoneal dialysate exposure modulates expression of membrane complement regulators in human peritoneal mesothelial cells.TIF by Kazuma Kobayashi (817168)

“…Analyzing Met-5A cells, we observed that expressions of the three CRegs were increased by glucose and lactic acid in a concentration-dependent manner, but conversely that expressions of CRegs were decreased by lower pH stimulation. …”

Image_2_Long-term peritoneal dialysate exposure modulates expression of membrane complement regulators in human peritoneal mesothelial cells.TIF by Kazuma Kobayashi (817168)

“…Analyzing Met-5A cells, we observed that expressions of the three CRegs were increased by glucose and lactic acid in a concentration-dependent manner, but conversely that expressions of CRegs were decreased by lower pH stimulation. …”

Secondary structure probabilities. by Vinal V. Lakhani (249536)

Supplementary Material for: Analysis of Geographic and Environmental Factors and Their Association with Cutaneous Melanoma Incidence in Canada by Berman-Rosa M. (12842984)

Cytotoxic effect of antimicrobial peptides is related to the entry of peptides but not with the binding to the cell membrane. by Marcus V. Buri (491139)

WV phase space projection for QIF model with spike waveform, and convergent iterative theoretical predictions for <i>μ</i> > <i>μ</i>* and <i>μ</i> → 0. by Adam D. Schneider (148548)

“…Inset shows the cyan trajectory in terms of decaying variables <i>x</i>*(<i>t</i>) and <i>C</i>*(<i>t</i>), and how <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0159300#pone.0159300.e084" target="_blank">Eq (22)</a> captures the initial increase and then decrease in the calcium concentration, while <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0159300#pone.0159300.e083" target="_blank">Eq (21)</a> does not. …”

Effects of Acute Tryptophan Depletion on Brain Serotonin Function and Concentrations of Dopamine and Norepinephrine in C57BL/6J and BALB/cJ Mice by Caroline Sarah Biskup (163085)

“…<div><p>Acute tryptophan depletion (ATD) is a method of lowering brain serotonin (5-HT). Administration of large neutral amino acids (LNAA) limits the transport of endogenous tryptophan (TRP) across the blood brain barrier by competition with other LNAAs and subsequently decreases serotonergic neurotransmission. …”

Visualization 1.mp4 by Laurent Lamaignère (3959429)

“…During the sequence the vertical oscilloscope range of the BSBS is reduced step by step in order to keep the temporal profile visible on the screen (3V [0-35sec.]; 1V [35-65sec.]; 0.5V [65-70sec.]; 0.20 V [70-100sec.]); 0.025 V [100-134sec.]).…”

Ultrasensitive SLIM Serpentine Ultra-long Path with Extended Routing (SUPER) high resolution ion mobility-MS using large ion populations and peak compression (ASMS 2017) by PNNL Omics (4106851)

Impact of transmissibility of the oncoming reassortant strain and cross-immunity induced by seasonal flu vaccination on the annual emergence probability of pandemic strain via reas... by Xu-Sheng Zhang (672653)

“…Here we consider a situation of cross-immunity structure where the cross-immunity conferred by vaccination are less than or equal to that by natural infection: <i>φ</i>:<i>ψ</i>:<i>φ</i>_V:<i>ψ</i>_V<i> = </i>0.5:0.5:0.1:0.1 (red), and 0.5:0.5:0.5:0.1 (yellow), 0.5:0.5:0.5:0.5 (green). …”

Increasing dead cell burden in wounds resulted in increased pro-inflammatory cytokine levels. by Savita Khanna (252283)

“…Data (mean ±SD, n = 5) are presented as <i>pg</i> cytokine per <i>mg</i> wound tissue. *, <i>p</i><0.05 compared to IgG treated control side.…”

Jackknife analysis of the top environmental predictors used in the model. by Kylie M. Sage (4543402)

“…BIO5 = maximum temperature of the warmest month, BIO6 = minimum temperature of the coldest month, BIO8 = mean temperature of the wettest quarter, BIO7 = annual temperature range, BIO15 = precipitation seasonality, BIO18 = precipitation of the warmest quarter, elv = elevation.…”

Association of the Sirtuin and Mitochondrial Uncoupling Protein Genes with Carotid Plaque by Chuanhui Dong (197539)

“…After adjustment for demographic and vascular risk factors, T-carriers of the SIRT6 SNP rs107251 had an increased risk for carotid plaque (odds ratio, OR = 1.71, 95% CI = 1.23–2.37, Bonferroni-corrected p = 0.03) and for a number of plaques (rate ratio, RR = 1.31, 1.18–1.45, Bonferroni-corrected p = 1.4×10⁻⁵), whereas T-carriers of the UCP5 SNP rs5977238 had an decreased risk for carotid plaque (OR = 0.49, 95% CI = 0.32–0.74, Bonferroni-corrected p = 0.02) and plaque number (RR = 0.64, 95% CI = 0.52–0.78, Bonferroni-corrected p = 4.9×10⁻⁴). …”

RAB7 activity is required for the regulation of mitophagy in oocyte meiosis and oocyte quality control during ovarian aging by Xin Jin (108988)

Climate change dataset. by Serge Wiltshire (6597761)

“…We use downscaled climate projections from four Global Climate Models, forced by RCP 4.5, that bracket the range of likely climate change. …”

GIS input dataset. by Serge Wiltshire (6597761)

“…We use downscaled climate projections from four Global Climate Models, forced by RCP 4.5, that bracket the range of likely climate change. …”

Effect of oral potassium supplementation on urinary potassium excretion and its diagnostic value for primary aldosteronism by Ke Zhang (115386)

“…Urinary-to-serum potassium ratio (USR) decreased in 40% of patients, while it increased by 0–5, 5–10, and > 10 L/24 h in 25%, 25%, and 10% of patients, respectively. …”

siRNAs targeted to mouse IGF-IR in breast cancer cells. by Tiphanie Durfort (189574)

Differential Development of Human Brain White Matter Tracts by Davide Imperati (207531)

“…Specifically, using a cross-sectional sample comprising 144 healthy individuals (7 to 48 years old), we applied k-means cluster analysis to separate white matter voxels based on their age-related trajectories of fractional anisotropy. …”