Table_1_Changes in Symbiotic Microbiota and Immune Responses in Early Development Stages of Rapana venosa (Valenciennes, 1846) Provide Insights Into Immune System Development in Ga... by Mei-Jie Yang (8978381)

“…The abundance of immune-related KEGG Orthologs (KOs) also increased in competent larval (J4, 30-day post-hatching) and postlarval after 3 days of metamorphosis (Y5, 33-day post-hatching) stages. Acid phosphatase activity decreased significantly in the Y5 stage, and alkaline phosphatase activity also at a lower level in Y5 stage, whereas lysozyme activities exhibited no remarkable change. …”

Image_2_Roles of Cadherin2 in Thyroid Cancer.tif by Yun Chen (279569)

“…Moreover, CDH2 and FRMD3 expression were significantly higher in tumor tissues than in normal tissues, while hsa-miR-410-3p, hsa-miR-411-5p and hsa-miR-299-5p were significantly decreased in tumor tissues compared with normal tissues in THCA. …”

Table_1_Roles of Cadherin2 in Thyroid Cancer.docx by Yun Chen (279569)

“…Moreover, CDH2 and FRMD3 expression were significantly higher in tumor tissues than in normal tissues, while hsa-miR-410-3p, hsa-miR-411-5p and hsa-miR-299-5p were significantly decreased in tumor tissues compared with normal tissues in THCA. …”

Image_1_Roles of Cadherin2 in Thyroid Cancer.tif by Yun Chen (279569)

“…Moreover, CDH2 and FRMD3 expression were significantly higher in tumor tissues than in normal tissues, while hsa-miR-410-3p, hsa-miR-411-5p and hsa-miR-299-5p were significantly decreased in tumor tissues compared with normal tissues in THCA. …”

Table_1_Novel Volumetric and Surface-Based Magnetic Resonance Indices of the Aging Brain – Does Male and Female Brain Age in the Same Way?.XLSX by Przemysław Podgórski (7325084)

“…</p><p>Results: In men and women, a decrease in GM and WM volumes and an increase in CSF volume seem to progress slowly since the age of 45. …”

Data_Sheet_1_Transformation of Plant to Resource Acquisition Under High Nitrogen Addition Will Reduce Green Roof Ecosystem Functioning.docx by Qinze Zhang (12554101)

“…We highlight that there is a trade-off between the survival of green roof species and keeping the ecosystem functioning well in the future N deposition. …”

Neonatal Maternal Deprivation Response and Developmental Changes in Gene Expression Revealed by Hypothalamic Gene Expression Profiling in Mice by Feng Ding (33360)

“…Unlike in adult rodents, expression levels of <em>Nanos2</em> and <em>Pdk4</em> were increased, and those of <em>Pgpep1</em>, <em>Ndp</em>, <em>Brms1l</em>, <em>Mett10d</em>, and <em>Snx1</em> were decreased after neonatal deprivation. In addition, we compared hypothalamic gene expression profiles at postnatal days 5 and 13 and observed significant developmental changes. …”

HILIC positive mode QC and Blanks raw data by Haley Chatelaine (12134238)

“…<div><br></div><div>Extracts (10 uL) were analyzed with HILIC-LC-MS using an Agilent Poroshell 120 HILIC-Z column (2.1 x 100 mm, 1.9 um particle size) at 35 C. Solvent A: 95/5 water/acetonitrile with 0.2% acetic acid and 5 mM ammonium acetate; Solvent B: 95/5 acetonitrile/water with 0.2% acetic acid and 5 m M ammonium acetate. …”

HILIC Positive Mode Sample Raw Data by Haley Chatelaine (12134238)

“…<div><br></div><div>Extracts (10 uL) were analyzed with HILIC-LC-MS using an Agilent Poroshell 120 HILIC-Z column (2.1 x 100 mm, 1.9 um particle size) at 35 C. Solvent A: 95/5 water/acetonitrile with 0.2% acetic acid and 5 mM ammonium acetate; Solvent B: 95/5 acetonitrile/water with 0.2% acetic acid and 5 m M ammonium acetate.…”

Novel, selective EPO receptor ligands lacking erythropoietic activity reduce infarct size in acute myocardial infarction in rats by Kiss, K.

“…In a pilot study, EPO at 100 U/mL significantly decreased cell death compared to vehicle (33.8 ± 2.3% vs. 40.3 ± 1.5%, p < 0.05) in rat neonatal cardiomyocytes subjected to simulated ischemia/reperfusion. …”
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1561_pHW_Perth09-HA-G78D-T212I.gb by Valerie Le Sage (10669206)

“…Mutations in the HA head at positions 78 and 212 of A/Perth/16/2009 (H3N2), which were selected after cell culture adaptation, decreased the acid stability of the virus from pH 5.5 (WT) to pH 5.8 (mutant). …”

Computational Analysis of The Performance of Shaft Furnaces with Partial Replacement of The Burden with Self-Reducing Pellets Containing Biomass by Elisa Pinto da Rocha (8558124)

“…The simulation results for a combination of 15% of self-reducing pellets in the burden with 2.5% oxygen and natural gas injection were the best among the scenarios simulated, with the productivity being 2.7 ton/m3 day and the decrease in the amount of reformed gas being 10%.…”

Antiviral therapies and viral strain affect COVID-19 severity. by Chrysovalantis Voutouri (612840)

“…<p><u>D</u>iagrams of peak viral load (A) and minimum oxygen saturation (SpO₂) (B) caused by viral infection as a function of viral immune evasion and relative decrease of virus replication rate, K_in, with antiviral drugs. ’Favorable’ outcomes for viral load correspond to low concentrations, while ’unfavorable’ outcomes relate to high concentrations. …”

Time-dependence of the HMGB1-induced suppression of cellular bioenergetics in RAW 264.7 macrophages. by Domokos Gerö (422086)

“…<b>A:</b> Time-dependent decrease in basal cellular respiration (Oxygen Consumption Rate, OCR). …”

Data_Sheet_1_Chronic Δ9-tetrahydrocannabinol impact on plasticity, and differential activation requirement for CB1-dependent long-term depression in ventral tegmental area GABA neu... by Isaac Ostlund (14349531)

“…In young mice, VTA GABA cells exhibit a form of synaptic plasticity known as long-term depression (LTD) that is dependent on cannabinoid 1 (CB1) receptors preceded by metabotropic glutamate receptor 5 (mGluR5) signaling to induce endocannabinoid production. …”

Overlap of epigenetic signatures and Hi-C contacts. by Ittai E. Eres (7010684)

“…<p>(A) Hi-C loci that do not make contact with promoters are ranked in order of decreasing DC FDR (x-axis). …”

Image_1_Identification of Immune-Related Gene Signature and Prediction of CeRNA Network in Active Ulcerative Colitis.tif by Mengmeng Xu (1696420)

“…RT-PCR revealed that andrographolide (AGP) significantly inhibited the expression of hub genes. Finally, we identified XIST and three miRNAs (miR-9-5p, miR-129-5p, and miR-340-5p) as therapeutic targets.…”

Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis by Lorena Fernandez-Mosquera (5077820)

“…</p> <p><b>Abbreviation</b>: ΔΨ_m: mitochondrial transmembrane potential; AMP: adenosine monophosphate; AMPK: AMP-activated protein kinase; ATG5: autophagy related 5; ATP: adenosine triphosphate; ATP6V0A1: ATPase, H+ transporting, lysosomal, V0 subbunit A1; ATP6V1A: ATPase, H+ transporting, lysosomal, V0 subbunit A; BSA: bovine serum albumin; CCCP: carbonyl cyanide-m-chlorophenylhydrazone; CREB1: cAMP response element binding protein 1; CTSD: cathepsin D; CTSF: cathepsin F; DMEM: Dulbecco’s modified Eagle’s medium; DMSO: dimethyl sulfoxide; EBSS: Earl’s balanced salt solution; ER: endoplasmic reticulum; FBS: fetal bovine serum; FCCP: carbonyl cyanide-p-trifluoromethoxyphenolhydrazone; GFP: green fluorescent protein; GPN: glycyl-L-phenylalanine 2-naphthylamide; LAMP1: lysosomal associated membrane protein 1; MAP1LC3B/LC3B: microtubule associated protein 1 light chain 3 beta; MCOLN1/TRPML1: mucolipin 1; MEF: mouse embryonic fibroblast; MITF: melanocyte inducing transcription factor; ML1N*2-GFP: probe used to detect PtdIns(3,5)P₂ based on the transmembrane domain of MCOLN1; MTORC1: mechanistic target of rapamycin kinase complex 1; NDUFS4: NADH:ubiquinone oxidoreductase subunit S4; OCR: oxygen consumption rate; PBS: phosphate-buffered saline; pcDNA: plasmid cytomegalovirus promoter DNA; PCR: polymerase chain reaction; PtdIns3P: phosphatidylinositol-3-phosphate; PtdIns(3,5)P₂: phosphatidylinositol-3,5-bisphosphate; PIKFYVE: phosphoinositide kinase, FYVE-type zinc finger containing; P/S: penicillin-streptomycin; PVDF: polyvinylidene fluoride; qPCR: quantitative real time polymerase chain reaction; RFP: red fluorescent protein; RNA: ribonucleic acid; SDS-PAGE: sodium dodecyl sulfate polyacrylamide gel electrophoresis; shRNA: short hairpin RNA; siRNA: small interfering RNA; TFEB: transcription factor EB; TFE3: transcription factor binding to IGHM enhancer 3; TMRM: tetramethylrhodamine, methyl ester, perchlorate; ULK1: unc-51 like autophagy activating kinase 1; ULK2: unc-51 like autophagy activating kinase 2; UQCRC1: ubiquinol-cytochrome c reductase core protein 1; v-ATPase: vacuolar-type H+-translocating ATPase; WT: wild-type</p>…”

Data_Sheet_1_Identification of Biologically Active Ganoderma lucidum Compounds and Synthesis of Improved Derivatives That Confer Anti-cancer Activities in vitro.docx by Michelle M. Martínez-Montemayor (383853)

“…Three of the seven compounds (ergosterol, 5,6-dehydroergosterol and ergosterol peroxide) exhibited significant in vitro anti-cancer activities, while we report for the first time the structure elucidation of 5,6-dehydroergosterol from Ganoderma lucidum. …”

Lysosomal BK channels facilitate silica-induced inflammation in macrophages by Rebekah L. Kendall (14605289)