Supplementary Material for: Quantitative Proteomics Analysis of Ischemia/Reperfusion Injury-Modulated Proteins in Cardiac Microvascular Endothelial Cells and the Protective Role of... by Li Q. (2850350)

“…Also, TXL down-regulated 5 proteins including angiopoietin-2 isoform c precursor (ANGPT2), cytochrome c oxidase assembly factor 5 (COA5), connective tissue growth factor precursor (CTGF), cathepsin L1 isoform 2 (CTSL), and eukaryotic elongation factor 2 kinase (LOC101930123). …”

REST KD results in altered signaling including an increase in MEK and WNT activity in embryoid bodies (EBs). by Kaushali Thakore-Shah (839203)

“…Significant changes in expression of WNT target genes in REST KD Day 5 EBs are shown with two asterisks (**). Across both lines of REST KD Day 5 EBs, we found a statistically significant increase in expression of WNT target genes AXIN2, B-CAT and TROY (p<0.022). …”

Table 1_Burden of esophageal cancer in global, regional and national regions from 1990 to 2021 and its projection until 2050: results from the GBD study 2021.docx by Chengcheng Zhang (725743)

“…Background<p>Esophageal cancer (EC) is a major global health issue characterized by high morbidity and mortality rates, with a notably low five-year survival rate. …”

3HA Nanoparticle Stability Data by Timothy Chang (4727196)

Google form data_ Public awareness and acceptance of COVID-19 vaccine: An online cross-sectional survey, conducted in the first phase of vaccination drive in India by Arumuganainar Suresh (10582049)

“…The total knowledge score ranged from 0 to 7; a cut-off score of <4 was set as ‘poor’ and >5, ‘good’ knowledge. …”

Table_1_Different functional lung-sparing strategies and radiotherapy techniques for patients with esophageal cancer.xlsx by Pi-Xiao Zhou (12886184)

“…The 2F-VMAT had higher PTV conformability and homogeneity and decreased FL-D_mean, V₅-₂₀ and Lungs-D_mean, V₅-₁₀ but correspondingly increased spinal cord-D_mean compared with those of the 5F-IMRT planning (P< 0.05).…”

DataSheet_1_Different functional lung-sparing strategies and radiotherapy techniques for patients with esophageal cancer.docx by Pi-Xiao Zhou (12886184)

“…The 2F-VMAT had higher PTV conformability and homogeneity and decreased FL-D_mean, V₅-₂₀ and Lungs-D_mean, V₅-₁₀ but correspondingly increased spinal cord-D_mean compared with those of the 5F-IMRT planning (P< 0.05).…”

Hypophosphatemia is an independent risk factor for AKI among hospitalized patients with COVID-19 infection by Zijin Chen (7338062)

“…Systemic renal tubular dysfunction was evaluated <i>via</i> 24-h urine collections in a subgroup of 55 patients.</p> <p>In total, 823 patients were enrolled (50.5% male) with a mean age of 60.9 ± 14.9 years. …”

DataSheet1_Avasimibe Alleviates Disruption of the Airway Epithelial Barrier by Suppressing the Wnt/β-Catenin Signaling Pathway.PDF by Zicong Zhou (12075644)

“…However, its efficacy in asthma has not yet been reported. We first administered varying concentrations of avasimibe to house dust mite (HDM)-induced asthmatic mice; results showed that 20 mg/kg avasimibe most significantly reduced IL-4 and IL-5 production in bronchoalveolar lavage fluid (BALF) and total IgE in serum, and the avasimibe treatment also exhibited lower mucus secretion, decreased goblet and basal cells but increased ciliated cells compared to the HDM group. …”

Quinidine, but Not Eicosanoid Antagonists or Dexamethasone, Protect the Gut from Platelet Activating Factor-Induced Vasoconstriction, Edema and Paralysis by Ingmar Lautenschläger (706815)

“…A vascular bolus of PAF (0.5 nmol) triggered release of thromboxane and peptidoleukotrienes into the vascular bed (peak concentration 35 nM and 0.8 nM) and reproduced all symptoms of intestinal failure: mesenteric vasoconstriction, translocation of fluid and macromolecules from the vasculature to the lumen and lymphatics, intestinal edema formation, loss of intestinal peristalsis and decreased galactose uptake. …”

Presentation_1_Willin/FRMD6 Influences Mechanical Phenotype and Neuronal Differentiation in Mammalian Cells by Regulating ERK1/2 Activity.pdf by Nils M. Kronenberg (1696528)

“…By investigating cells with increased and decreased Willin/FRMD6 expression levels, we show that Willin/FRMD6 not only affects proliferation and migration capacity of cells but also leads to changes in cell morphology and an enhanced formation of neurite-like membrane extensions. …”

Supplementary Material for: The Effects of Early Postnatal Diuretics Treatment on Kidney Development and Long-Term Kidney Function in Wistar Rats by Bueters R.R.G. (3349739)

“…<p><b><i>Background:</i></b> Diuretics are administered to neonates to control fluid balance. We studied whether clinical doses affected kidney development and function and whether extrauterine growth retardation (EUGR) could be a modulator. …”

Blockade of ROMK currents by TPN-RQ and the lack of effect of Cys-to-Ser mutants. by Masayoshi Okada (288631)

“…<p>(A) Whole-cell ROMK currents were evoked by step-pulses, as shown in the protocol. …”

DataSheet_1_Glutathione S-Transferase Alpha 4 Promotes Proliferation and Chemoresistance in Colorectal Cancer Cells.pdf by Zhanhu Zhang (12984293)

“…Cell proliferation, clonogenicity, and susceptibility to chemotherapeutic drugs were analyzed in vitro and in a xenograft model. The results showed that loss of GSTA4 significantly decreased cell proliferation and clonogenicity, whereas it increased intracellular reactive oxygen species and cell susceptibility to 5-fluorouracil (5-FU) and oxaliplatin. …”

DataSheet_1_Glutathione S-Transferase Alpha 4 Promotes Proliferation and Chemoresistance in Colorectal Cancer Cells.pdf by Zhanhu Zhang (12984293)

“…Cell proliferation, clonogenicity, and susceptibility to chemotherapeutic drugs were analyzed in vitro and in a xenograft model. The results showed that loss of GSTA4 significantly decreased cell proliferation and clonogenicity, whereas it increased intracellular reactive oxygen species and cell susceptibility to 5-fluorouracil (5-FU) and oxaliplatin. …”

Data_Sheet_1_GPR171 Agonist Reduces Chronic Neuropathic and Inflammatory Pain in Male, But Not Female Mice.docx by Akila Ram (6842501)

“…Here, we explore the therapeutic potential of the GPR171 agonist, MS15203, in its ability to alleviate chronic pain in male and female mice using a once-daily systemic dose (10 mg/kg, i.p.) of MS15203 over the course of 5 days. …”

Simulation of SMARD experiment with comparison to rate-equation estimates. by Michel G. Gauthier (152223)

“…Each line corresponds to a molecule as the example presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0032053#pone-0032053-g005" target="_blank">Fig. 5 b</a>. …”

Supplementary Material for: Risk Factors and Outcomes of Emergency Room Visits in Intestinal Behçet’s Disease by Park J. (3112986)

“…<b><i>Results:</i></b> One hundred eighty-five patients (30.5%) visited the ER at least once (total visits, 510). …”

Reduced Dopamine Release in the Striatum of <i>DAT-Ret^lx/lx</i> Mice by Edgar R Kramer (274117)

“…There is a further significant decrease in the homozygous <i>DAT-Ret^lx/lx</i> mice due to the lack of Ret (<i>n</i> = 5 per genotype, <i>p</i> < 0.05, Student <i>t</i>-test). *, <i>p</i> < 0.05; **, <i>p</i> < 0.01 (Student <i>t</i>-test). …”

table_1_In Utero and Postnatal Propylthiouracil-Induced Mild Hypothyroidism Impairs Maternal Behavior in Mice.DOCX by Miski Aghnia Khairinisa (5213834)

“…The decrease in maternal behavior was significantly correlated with a decrease in cognition. …”