The Type 2 Diabetes Risk Allele of <i>TMEM154</i>-rs6813195 Associates with Decreased Beta Cell Function in a Study of 6,486 Danes by Marie Neergaard Harder (232759)

“…Significant associations between <i>TMEM154</i>-rs6813195 and the beta cell measures insulinogenic index and disposition index and between <i>FAF1</i>-rs17106184 and 2-hour serum insulin levels were selected for further investigation in additional Danish studies and results were combined in meta-analyses including up to 6,486 Danes.</p><p>Results</p><p>We confirmed associations with type 2 diabetes for five of the seven SNPs (<i>TMEM154</i>-rs6813195, <i>FAF1</i>-rs17106184, <i>POU5F1/TCF19</i>-rs3130501, <i>ARL15</i>-rs702634 and <i>ABCB9/MPHOSPH9</i>-rs4275659). …”

Statins Decrease Neuroinflammation and Prevent Cognitive Impairment after Cerebral Malaria by Patricia A. Reis (109310)

<i>neurod1</i>^<i>ΔUCE</i> homozygous mutants display an increase of the goblet cells concomitant with a decrease of EECs. by Anne Sophie Reuter (12239993)

Participants characteristics. by Sakiko Fukui (387048)

“…</p><p>Methods</p><p>Sixty-nine deceased older adults from five special nursing homes were studied over 3.5 years (January 2016 to June 2020). …”

Optogenetic Recruitment of Dorsal Raphe Serotonergic Neurons Acutely Decreases Mechanosensory Responsivity in Behaving Mice by Guillaume P. Dugué (620333)

“…<i>In vivo</i>, the photoactivation of dorsal raphe serotonergic neurons gave rise to a prominent light-evoked field response that displayed some sensitivity to a 5-HT1A agonist, consistent with autoreceptor inhibition of raphe neurons. …”

The image illustrates the five steps of the experiment. by Deborah Ribeiro Frazão (9188152)

LC-IMS-CID-MS CKO vs K5Cre results. by Kevin J. Mills (9270966)

“…<div><p>CCAAT/enhancer binding protein- (C/EBP) is a basic leucine zipper transcription factor that is abundantly expressed in epidermal keratinocytes of skin. …”

Data_Sheet_1_Decrease in COVID-19 adverse outcomes in adults during the Delta and Omicron SARS-CoV-2 waves, after vaccination in Mexico.docx by Lenin Domínguez-Ramírez (481547)

“…In this scenario of high SARS-CoV-2 circulation, we analyzed the effectiveness of the country's vaccination strategy that used 7 different vaccines from around the world, and focused on vaccinating the oldest population first. …”

Image_5_Catheter-Based Therapies Decrease Mortality in Patients With Intermediate and High-Risk Pulmonary Embolism: Evidence From Meta-Analysis of 65,589 Patients.TIF by Arkadiusz Pietrasik (12879863)

“…Background<p>Catheter-directed therapies (CDT) are an alternative to systemic thrombolysis (ST) in pulmonary embolism (PE) patients, but the mortality benefit of CDT is unclear.</p>Objective<p>We conducted a systematic review with meta-analysis to compare the efficacy and safety of CDT and ST in intermediate-high and high-risk PE.…”

Anion-Assisted Glycosylation of Galactose: A Computational Study by Kerli Tali (22769704)

Panel (a) compares SO₂ emissions prescribed over the historical period in the CMIP5 simulations (solid grey) with three inventory-based estimates of historical emissions... by Nathan P Gillett (557010)

“…<p><strong>Figure 1.</strong> Panel (a) compares SO₂ emissions prescribed over the historical period in the CMIP5 simulations (solid grey) with three inventory-based estimates of historical emissions [<a href="http://iopscience.iop.org/1748-9326/8/3/034008/article#erl467068bib1" target="_blank">1</a>, <a href="http://iopscience.iop.org/1748-9326/8/3/034008/article#erl467068bib10" target="_blank">10</a>, <a href="http://iopscience.iop.org/1748-9326/8/3/034008/article#erl467068bib11" target="_blank">11</a>]. …”

Flow chart of the expression-based functional screen, with validation steps. by Mohamad Karaky (8910497)

Subjects:

Sensitivity of the PCR for decreasing concentrations of genomic DNA purified from <i>Veillonella</i> species using species-specific primer sets. by Izumi Mashima (3165120)

Major steps of the polyamine metabolism in <i>E. coli</i>. by Rosaria Campilongo (626526)

DataSheet1_Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex.docx by Wesam S. Ahmed (10170053)

DataSheet1_Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex.docx by Wesam S. Ahmed (10170053)

Image_5_Eliminating the VGlut2-Dependent Glutamatergic Transmission of Parvalbumin-Expressing Neurons Leads to Deficits in Locomotion and Vocalization, Decreased Pain Sensitivity,... by Diana M. Roccaro-Waldmeyer (5532074)

Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease by Christine M. LaPash Daniels (796881)

“…Here we tested whether lithium treatment would decrease levels of GFAP in a mouse model of Alexander disease. …”

Image 2_Probiotic Limosilactobacillus reuteri KUB-AC5 decreases urothelial cell invasion and enhances macrophage killing of uropathogenic Escherichia coli in vitro study.tiff by Arishabhas Tantibhadrasapa (13929639)

“…The human bladder epithelial cell line UM-UC-3 was used to assess the adhesion and pathogen-attachment inhibition properties of AC5 on UPEC.</p>Results and discussion<p>Our data showed that AC5 can attach to UM-UC-3 and decrease UPEC attachment in a dose-dependent manner. …”

Table 1_Probiotic Limosilactobacillus reuteri KUB-AC5 decreases urothelial cell invasion and enhances macrophage killing of uropathogenic Escherichia coli in vitro study.xlsx by Arishabhas Tantibhadrasapa (13929639)

“…The human bladder epithelial cell line UM-UC-3 was used to assess the adhesion and pathogen-attachment inhibition properties of AC5 on UPEC.</p>Results and discussion<p>Our data showed that AC5 can attach to UM-UC-3 and decrease UPEC attachment in a dose-dependent manner. …”