Showing 641 - 660 results of 100,889 for search '(( 5 we decrease ) OR ( 5 ((((wt decrease) OR (nn decrease))) OR (a decrease)) ))', query time: 1.38s Refine Results
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    SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue by Dorota Kmiec (5646374)

    Published 2018
    “…Here, we show that the Nef protein of the highly divergent SIVcol lineage infecting mantled guerezas (<i>Colobus guereza</i>) is a potent antagonist of SERINC5, although it lacks the CD4, CD3 and CD28 down-modulation activities exerted by other primate lentiviral Nefs. …”
  11. 651

    Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

    Published 2022
    “…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
  12. 652

    Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

    Published 2022
    “…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
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    Theoretical Study on Reaction Scheme of Silver(I) Containing 5-Substituted Uracils Bridge Formation by Toru Matsui (1313913)

    Published 2011
    “…We present a reaction scheme of silver containing 5-substituted uracils (<b>N</b>) bridge formation with two silver ions to a silver-mediated base pair [<b>N</b>-Ag<sub>2</sub>-<b>N</b>] by using the conductor-like polarizable continuum model (CPCM)-B3LYP/aug-cc-pVDZ level of theory. …”
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