Showing 1,761 - 1,780 results of 100,889 for search '(( 5 we decrease ) OR ( 5 ((((wt decrease) OR (nn decrease))) OR (a decrease)) ))', query time: 1.60s Refine Results
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    Table_1_When and Why Did Human Brains Decrease in Size? A New Change-Point Analysis and Insights From Brain Evolution in Ants.XLSX by Jeremy M. DeSilva (7247009)

    Published 2021
    “…<p>Human brain size nearly quadrupled in the six million years since Homo last shared a common ancestor with chimpanzees, but human brains are thought to have decreased in volume since the end of the last Ice Age. …”
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    Identification of a Hydroxypyrimidinone Compound (<b>21</b>) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure by Wei Meng (505670)

    Published 2021
    “…Due to the increased polarity at C2, the permeability for these compounds decreased. Further adjustment of the polarity by replacing the N1 2,6-dimethoxyphenyl group with a 2,6-diethylphenyl group and reoptimization for the potency of the C5 pyrroloamides resulted in potent compounds with improved permeability. …”
  7. 1767

    Identification of a Hydroxypyrimidinone Compound (<b>21</b>) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure by Wei Meng (505670)

    Published 2021
    “…Due to the increased polarity at C2, the permeability for these compounds decreased. Further adjustment of the polarity by replacing the N1 2,6-dimethoxyphenyl group with a 2,6-diethylphenyl group and reoptimization for the potency of the C5 pyrroloamides resulted in potent compounds with improved permeability. …”
  8. 1768

    Identification of a Hydroxypyrimidinone Compound (<b>21</b>) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure by Wei Meng (505670)

    Published 2021
    “…Due to the increased polarity at C2, the permeability for these compounds decreased. Further adjustment of the polarity by replacing the N1 2,6-dimethoxyphenyl group with a 2,6-diethylphenyl group and reoptimization for the potency of the C5 pyrroloamides resulted in potent compounds with improved permeability. …”
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    Photo-affinity labelling and biochemical analyses identify the target of trypanocidal simplified natural product analogues by Lindsay B. Tulloch (1266861)

    Published 2017
    “…<div><p>Current drugs to treat African sleeping sickness are inadequate and new therapies are urgently required. As part of a medicinal chemistry programme based upon the simplification of acetogenin-type ether scaffolds, we previously reported the promising trypanocidal activity of <b>compound 1</b>, a bis-tetrahydropyran 1,4-triazole (B-THP-T) inhibitor. …”
  13. 1773

    Kinetic and equilibrium constants for binding of WT and mutant FVIII-C2 proteins to BO2C11. by Jasper C. Lin (685807)

    Published 2015
    “…<sup>†</sup>These substitutions resulted in a k<sub>d</sub> >4X that of WT-FVIII-C2 for BO2C11 or abrogated binding to BO2C11. …”
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    Table_1_Effectiveness of Improved Use of Chewing Gum During Capsule Endoscopy in Decreasing Gastric Transit Time: A Prospective Randomized Controlled Study.XLS by Liang Huang (114017)

    Published 2021
    “…<p>Background/Aim: Chewing gum throughout small bowel capsule endoscopy (SBCE) increases completion rates (CRs) but decreases small bowel transit time (SBTT) and diagnostic yield (DY). …”
  18. 1778

    Table_1_Effectiveness of Improved Use of Chewing Gum During Capsule Endoscopy in Decreasing Gastric Transit Time: A Prospective Randomized Controlled Study.XLS by Liang Huang (114017)

    Published 2022
    “…<p>Background/Aim: Chewing gum throughout small bowel capsule endoscopy (SBCE) increases completion rates (CRs) but decreases small bowel transit time (SBTT) and diagnostic yield (DY). …”
  19. 1779

    Data Sheet 1_Lack of association between genetic variations in CYP3A5 and blood pressure or hypertension risk in the UK biobank.pdf by Pia Leibold (21390134)

    Published 2025
    “…While some previous studies reported that CYP3A5 variants were associated with decreased blood pressure and risk of HTN, others reported no associations. …”
  20. 1780

    A Unique Modification of the Eukaryotic Initiation Factor 5A Shows the Presence of the Complete Hypusine Pathway in <em>Leishmania donovani</em> by Bhavna Chawla (176976)

    Published 2012
    “…<div><p>Deoxyhypusine hydroxylase (DOHH) catalyzes the final step in the post-translational synthesis of an unusual amino acid hypusine (<em>N</em><sup>€</sup>-(4-amino-2-hydroxybutyl) lysine), which is present on only one cellular protein, eukaryotic initiation factor 5A (eIF5A). We present here the molecular and structural basis of the function of DOHH from the protozoan parasite, <em>Leishmania donovani,</em> which causes visceral leishmaniasis. …”