Image_8_A Novel Therapeutic Mechanism of Imipridones ONC201/ONC206 in MYCN-Amplified Neuroblastoma Cells via Differential Expression of Tumorigenic Proteins.TIF by Sarra El-Soussi (11228799)

“…The protein expression of tumorigenic NMYC, Sox-2, Oct-4, FABP5, and HMGA1 significantly decreased 48 h post-drug treatment, whereas cleaved PARP1/caspase-3 and γH2AX increased 72 h post-drug treatment, compared with vehicle-treated cells in the MYCN-amplified IMR-32 cell line. …”

Image_9_A Novel Therapeutic Mechanism of Imipridones ONC201/ONC206 in MYCN-Amplified Neuroblastoma Cells via Differential Expression of Tumorigenic Proteins.TIF by Sarra El-Soussi (11228799)

“…The protein expression of tumorigenic NMYC, Sox-2, Oct-4, FABP5, and HMGA1 significantly decreased 48 h post-drug treatment, whereas cleaved PARP1/caspase-3 and γH2AX increased 72 h post-drug treatment, compared with vehicle-treated cells in the MYCN-amplified IMR-32 cell line. …”

Image_2_A Novel Therapeutic Mechanism of Imipridones ONC201/ONC206 in MYCN-Amplified Neuroblastoma Cells via Differential Expression of Tumorigenic Proteins.TIF by Sarra El-Soussi (11228799)

“…The protein expression of tumorigenic NMYC, Sox-2, Oct-4, FABP5, and HMGA1 significantly decreased 48 h post-drug treatment, whereas cleaved PARP1/caspase-3 and γH2AX increased 72 h post-drug treatment, compared with vehicle-treated cells in the MYCN-amplified IMR-32 cell line. …”

Image_3_A Novel Therapeutic Mechanism of Imipridones ONC201/ONC206 in MYCN-Amplified Neuroblastoma Cells via Differential Expression of Tumorigenic Proteins.TIF by Sarra El-Soussi (11228799)

“…The protein expression of tumorigenic NMYC, Sox-2, Oct-4, FABP5, and HMGA1 significantly decreased 48 h post-drug treatment, whereas cleaved PARP1/caspase-3 and γH2AX increased 72 h post-drug treatment, compared with vehicle-treated cells in the MYCN-amplified IMR-32 cell line. …”

RT-qPCR evaluation of MYD88, NLRP3, and NFκβ in GA 18.5 pup brains. by Adrienne J. Bradley (20861948)

Bidirectional grey-matter CBF changes induced by a hypercapnic challenge. by Juliana Zimmermann (10507091)

Real-time measurements of cAMP in response to IBMX in control and AICAR-treated rat AVMs. by Anne Garnier (130125)

“…Following CFP excitation at 440±20nm, cAMP binding to the sensor induces a transient decrease in fluorescence resonance energy transfer (FRET) between CFP and YFP plotted as the ratio of the corrected CFP/YFP fluorescence (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0292015#sec002" target="_blank">Materials and Methods</a>). …”

Data_Sheet_5_Mitigation of soil nitrous oxide emissions during maize production with basalt amendments.XLSX by Isabella Chiaravalloti (16416297)

Relative risk of all-cause mortality following SARS-CoV-2 infection in people with preexisting mental disorders. by Tomáš Formánek (19139519)

Subjects:

Relative risk of death with COVID-19 following SARS-CoV-2 infection in people with preexisting mental disorders. by Tomáš Formánek (19139519)

Subjects:

Image_5_Distinct impacts of fat and fructose on the liver, muscle, and adipose tissue metabolome: An integrated view.pdf by Maria João Meneses (13259739)

Salinomycin enhances doxorubicin sensitivity through reversing the epithelial-mesenchymal transition of cholangiocarcinoma cells by regulating ARK5 by Z. Yu (1274130)

“…We found that combined salinomycin with doxorubicin treatment resulted in a significant decrease in cell viability compared with doxorubicin or salinomycin treatment alone in two cholangiocarcinoma cell lines (RBE and Huh-28). …”

Table_5_Delayed Meal Timing, a Breakfast Skipping Model, Increased Hepatic Lipid Accumulation and Adipose Tissue Weight by Disintegrating Circadian Oscillation in Rats Fed a High-C... by Daeun Kim (4967644)

The effect of caffeine on cutaneous postocclusive reactive hyperaemia - Fig 5 by Ziva Melik (6564905)

Evidence for selection on SARS-CoV-2 RNA translation revealed by the evolutionary dynamics of mutations in UTRs and CDSs by Lin Zhu (192179)

“…Particularly, when viruses invade host cells, how to compete with endogenous RNAs for efficient translation is a major issue to be resolved. We collected millions of worldwide SARS-CoV-2 sequences during the past year and traced the dynamics of allele frequency of every mutation. …”

Data_Sheet_1_Approaches to Daily Monitoring of the SARS-CoV-2 Outbreak in Northern Italy.docx by Giovenale Moirano (8880101)

Presentation_1_GABAB Receptor-Mediated Regulation of Dendro-Somatic Synergy in Layer 5 Pyramidal Neurons.pdf by Jan M. Schulz (11330949)

“…Using partial information decomposition, we demonstrate here a substantial contribution of synergy between somatic and apical dendritic inputs to the information in the AP output of L5b pyramidal neurons. …”

DataSheet1_Socioeconomic Differences in SARS-CoV-2 Infection and Vaccination in Germany: A Seroepidemiological Study After One Year of COVID-19 Vaccination Campaign.docx by Susanne Bartig (16286924)

“…Combining serological and self-report data, we estimated adjusted prevalence ratios (PR) of SARS-CoV-2 infection, COVID-19 vaccination, basic immunization (at least two SARS-CoV-2 antigen contacts through vaccination and/or infection), and three antigen contacts by education and income.…”

DataSheet1_Socioeconomic Differences in SARS-CoV-2 Infection and Vaccination in Germany: A Seroepidemiological Study After One Year of COVID-19 Vaccination Campaign.docx by Susanne Bartig (16286924)

“…Combining serological and self-report data, we estimated adjusted prevalence ratios (PR) of SARS-CoV-2 infection, COVID-19 vaccination, basic immunization (at least two SARS-CoV-2 antigen contacts through vaccination and/or infection), and three antigen contacts by education and income.…”

Image_5_Alive Pathogenic and Saprophytic Leptospires Enter and Exit Human and Mouse Macrophages With No Intracellular Replication.tif by Ignacio Santecchia (4667080)