Image 2_Effects of m6A methylation of MAT2A mRNA regulated by METTL16 on learning and memory, hippocampal synaptic plasticity and Aβ1–42 in 5 × FAD mice.jpg by Huan Chen (6545)

“…Overexpression of METTL16 led to an increase in overall m⁶A methylation levels, furthermore, overexpression of either METTL16 or MAT2A enhanced learning and memory in 5 × FAD mice, elevated the expression levels of postsynaptic density 95 (PSD95) and synaptophysin (Syp), increased dendritic spine density, and decreased the accumulation of Aβ_1–42 in the hippocampus. …”

Primary and secondary outcomes of the randomized clinical trial groups at 3 months and 12 months. by Teemu P. Hevonkorpi (11577571)

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Baseline characteristics of 291 patients by randomization group. by Teemu P. Hevonkorpi (11577571)

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Adverse events at 12-month follow-up by study group. by Teemu P. Hevonkorpi (11577571)

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Participant flow diagram of the DRIFT trial. by Teemu P. Hevonkorpi (11577571)

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Between-group differences of mean PRWE with 95% confidence intervals in primarily malaligned DRFs and early malaligned DRFs at 3-month and 12-month follow-up. by Teemu P. Hevonkorpi (11577571)

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RAB-5 Controls the Cortical Organization and Dynamics of PAR Proteins to Maintain <em>C. elegans</em> Early Embryonic Polarity by Vincent Hyenne (169009)

“…Using Total Internal Reflection Fluorescence (TIRF) microscopy, we observed that PAR-6 is localized at the cell cortex in highly dynamic puncta and depleting RAB-5 decreased PAR-6 cortical dynamics during the polarity maintenance phase. …”

Effect of NAC on cell proliferation in C2C12 myoblasts. by Yi-Xuan Li (6633845)

Effects of levofloxacin on the spines of DBA/1 mice. by Susana Aideé González-Chávez (11495378)

A Cell-Based Assay for RNA Synthesis by the HCV Polymerase Reveals New Insights on Mechanism of Polymerase Inhibitors and Modulation by NS5A by C. T. Ranjith-Kumar (199732)

“…The inhibition by NS5A was decreased with the removal of the transmembrane helix in NS5B. …”

Data_Sheet_1_Functional Change of Effector Tumor-Infiltrating CCR5+CD38+HLA-DR+CD8+ T Cells in Glioma Microenvironment.docx by Pin-Yuan Chen (391703)

“…However, little is known about the characteristics of peripheral and tumor-infiltrating CD8⁺ T cells in patients with glioma. In this study, we examined the level of CD8⁺ T-cell activation in a group of 143 patients with glioma and determined that peripheral CD3⁺ T cells decreased in accordance with disease severity. …”

Locations of projected refugia for amphibians with 2°C and 4.5°C warming. by Rhosanna L. M. Jenkins (11167230)

Locations of projected refugia for plants with 2°C and 4.5°C warming. by Rhosanna L. M. Jenkins (11167230)

Locations of projected refugia for reptiles with 2°C and 4.5°C warming. by Rhosanna L. M. Jenkins (11167230)

Locations of projected refugia for birds with 2°C and 4.5°C warming. by Rhosanna L. M. Jenkins (11167230)

Locations of projected refugia for mammals with 2°C and 4.5°C warming. by Rhosanna L. M. Jenkins (11167230)

Effects of levofloxacin on the intestines of DBA/1 mice. by Susana Aideé González-Chávez (11495378)

OCP vs. time curves for P110 carbon steel corrosion in the absence and presence of different concentrations of (a) 5, (b) 6a and (c) 6b. by Ghadeer Mubarak (21567569)

Image3_Transcriptional, Electrophysiological, and Metabolic Characterizations of hESC-Derived First and Second Heart Fields Demonstrate a Potential Role of TBX5 in Cardiomyocyte Ma... by Arash Pezhouman (10725644)

“…Despite their therapeutic potential, the emergence of ventricular arrhythmias has limited their application. We previously developed a double reporter hESC line to isolate first heart field (FHF: TBX5⁺NKX2-5⁺) and second heart field (SHF: TBX5^-NKX2-5⁺) CMs. …”

Image2_Transcriptional, Electrophysiological, and Metabolic Characterizations of hESC-Derived First and Second Heart Fields Demonstrate a Potential Role of TBX5 in Cardiomyocyte Ma... by Arash Pezhouman (10725644)

“…Despite their therapeutic potential, the emergence of ventricular arrhythmias has limited their application. We previously developed a double reporter hESC line to isolate first heart field (FHF: TBX5⁺NKX2-5⁺) and second heart field (SHF: TBX5^-NKX2-5⁺) CMs. …”