Image_7_Promoter Hypomethylation and miR-145-5p Downregulation- Mediated HDAC11 Overexpression Promotes Sorafenib Resistance and Metastasis of Hepatocellular Carcinoma Cells.jpeg by Wenlong Wang (501114)

“…Our data indicate a role of miR-145-5p/HDAC11 axis in regulation of sorafenib resistance and metastasis in HCC.…”

Image_1_Promoter Hypomethylation and miR-145-5p Downregulation- Mediated HDAC11 Overexpression Promotes Sorafenib Resistance and Metastasis of Hepatocellular Carcinoma Cells.jpeg by Wenlong Wang (501114)

“…Our data indicate a role of miR-145-5p/HDAC11 axis in regulation of sorafenib resistance and metastasis in HCC.…”

Image_2_Promoter Hypomethylation and miR-145-5p Downregulation- Mediated HDAC11 Overexpression Promotes Sorafenib Resistance and Metastasis of Hepatocellular Carcinoma Cells.jpeg by Wenlong Wang (501114)

“…Our data indicate a role of miR-145-5p/HDAC11 axis in regulation of sorafenib resistance and metastasis in HCC.…”

Image_5_Mycobacterium tuberculosis Specific Protein Rv1509 Evokes Efficient Innate and Adaptive Immune Response Indicative of Protective Th1 Immune Signature.jpeg by Manjunath P (9365705)

Table_5_Transcriptome analysis revealed the expression levels of genes related to abscisic acid and auxin biosynthesis in grapevine (Vitis vinifera L.) under root restriction.XLS by Lei Wang (6656)

Sand fly Abundance Reduction (%)^a in the intervention site (Intervention site) during the post-intervention period by collection week, Tayasir, Palestine, July-September... by Samer Sawalha (5890535)

Effects of T5-1 and T5-12 on TAS2R5 expression during protein synthesis inhibition. by Donghwa Kim (252081)

“…In the presence of CHX, T5-1 caused a decrease in receptor expression with the prolonged exposure, while T5-12 exposure had no significant effect on expression. * , P < 0.01 vs vehicle control.…”

Fig 5 - by Kevin Tsai (197484)

“…Case 1 represents the scenario where the scaling factor <i>n</i> starts with 5 and increase to 12 in 5×10³ simulation time steps, and then decrease to 7 in 5×10³ simulation time steps. …”

Down-regulation of miR-340-5p promoted osteogenic differentiation through regulation of runt-related transcription factor-2 (RUNX2) in MC3T3-E1 cells by Xiaochen Wang (235611)

“…Luciferase assay indicated that RUNX2 may be a target gene of miR-340-5p. Moreover, RUNX2 deficiency decreased miR-340-5p inhibition-induced ALP activity, calcium accumulation and OCN, collagen-I, RUNX2 levels. …”

image_5_Glycogen Metabolism and Rheumatoid Arthritis: The Role of Glycogen Synthase 1 in Regulation of Synovial Inflammation via Blocking AMP-Activated Protein Kinase Activation.ti... by Maohua Shi (5564222)

Complement anaphylatoxin C5a neuroprotects through regulation of glutamate receptor subunit 2 and -2 by Piali Mukherjee (86993)

“…</p><p></p>ssion as assessed by GluR2 immunostaining in primary cultures from both WT and C5aRKO mice (n = 4). However, while WT primary cultures treated with glutamate and hrC5a (100 nM) which is able to neuroprotect significantly against glutamate neurotoxicity in WT cultures did not show significant decrease in GluR2, primary cultures from C5aR KO mice co-treated with glutamate and hrC5a showed significant decrease in the expression of GluR2. …”

image1_Jian-Pi-Yi-Shen Formula Ameliorates Oxidative Stress, Inflammation, and Apoptosis by Activating the Nrf2 Signaling in 5/6 Nephrectomized Rats.tif by Fanyuan Zhou (10431314)

“…However, the underlying mechanism has not been well elucidated. In the present study, we measured the markers of apoptosis, inflammation, oxidative stress, and nuclear factor erythroid 2–related factor 2 (Nrf2) signaling to investigate the effects of JPYS formula on renal function and fibrosis and its molecular mechanism in an established animal model of 5/6 nephrectomized (5/6Nx) rats. …”

table1_Jian-Pi-Yi-Shen Formula Ameliorates Oxidative Stress, Inflammation, and Apoptosis by Activating the Nrf2 Signaling in 5/6 Nephrectomized Rats.docx by Fanyuan Zhou (10431314)

“…However, the underlying mechanism has not been well elucidated. In the present study, we measured the markers of apoptosis, inflammation, oxidative stress, and nuclear factor erythroid 2–related factor 2 (Nrf2) signaling to investigate the effects of JPYS formula on renal function and fibrosis and its molecular mechanism in an established animal model of 5/6 nephrectomized (5/6Nx) rats. …”

Implementation strategies for PSBI treatment when a referral is not possible. by Gizachew Tadele Tiruneh (8407686)

Folic acid: a potential inhibitor against SARS-CoV-2 nucleocapsid protein by Yu-meng Chen (12575578)

“…This effect was decreased by 8.0% in the presence of SARS-CoV-2 N, indicating that SARS-CoV-2 N inhibits RNAi. …”

A schematic depicting the risk of infection from deposited virus-laden droplets and aerosols on porous fomites. by Eloise Parry-Nweye (7548998)

Table_5_Expansion of wastewater-based disease surveillance to improve health equity in California’s Central Valley: sequential shifts in case-to-wastewater and hospitalization-to-w... by Krystin F. Kadonsky (16471374)

“…WDS offers a cost-effective strategy to monitor trends in SARS-CoV-2 community infection rates.…”

Anti-C5a reduced IL-12⁺DCs in PBMC and LN. by Ning Ma (155058)

“…<p>(<b>A and B</b>) <b>IL-12⁺DCs cells decreased in PBMC and LN from anti-C5a-treated sepsis.…”

Epinephrine Activation of the β₂-Adrenoceptor Is Required for IL-13-Induced Mucin Production in Human Bronchial Epithelial Cells by Nour Al-Sawalha (768190)

“…Constitutive β₂AR activity was not sufficient for IL-13 induced mucin production and β-agonist-induced signaling is required. A clinically important long-acting β-agonist, formoterol, was as effective as epinephrine in potentiating IL-13 induced MUC5AC transcription. …”

Data Sheet 5_Assessing the disease burden of lower respiratory infections attributable to particulate matter pollution: trends from 1990 to 2021 and projections for 2022-2050.pdf by Erman Wu (19021269)

“…Regional heterogeneity was marked, with Central Sub-Saharan Africa bearing the highest HAP burden and minimal APMP improvement (EAPC: -0.24%). Children under 5 years of age group still accounted for the most PMP-related deaths, with the number decreasing from 851,458 (95% UI: 211,026 to 1,363,810) in 1990 to 201,078 (95% UI:61,817 to 337,232). …”