WNT3 decreases GCP proliferation by inhibiting SHH dependent gene transcription. by Sandrine L. Anne (489755)

“…<p>(<i>A</i>) WNT3 decreased proliferation of GCPs by 40.3± 5.0% of the control (Con) (n=3) as measured by [³H]-Thymidine incorporation assay. …”

<i>Zscan10</i> mutant females show decreased body weight. by Petra Kraus (190913)

Repeat peptide stimulated CD8+ T cells have decreased cytotoxic function. by Manzhi Zhao (9023381)

Zcchc11 deficiency decreases IGF-1 expression <i>in vivo</i>. by Matthew R. Jones (115795)

“…<p>(A) IGF-1 mRNA, measured by qRT-PCR, was decreased by Zcchc11 deficiency in 8-day-old livers. …”

Exposure to high temperatures decreases the lifespan of <i>Strongyloides</i> spp. FLFs. by Ben T. Gregory (20442502)

Mitochondrial function decreases in pasture-fed dairy cows during early lactation. by Mercedes García-Roche (6459200)

Inhibition of SNAI2 expression decreases the sensitivity to chemotherapy drugs of HCC cells. by Xin-Yu Zhao (3228756)

Decreased expression levels of the MYO6 protein in <i>ksv</i> mice. by Yuta Seki (4385833)

“…Expression of MYO6 is completely ablated in the hair cells of <i>Myo6</i>^-/- mice (C). Scale bar = 5 μm. D and E. Western blot analysis of homogenates prepared from the inner ears of +/+, +/<i>ksv</i> and <i>ksv/ksv</i> mice at P30 detected with anti-MYO6 (N-ter, D) and MYO6 (C-ter, E) antibodies (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0183477#pone.0183477.s007" target="_blank">S2 Table</a>). …”

Decreased Integrity, Content, and Increased Transcript Level of Mitochondrial DNA Are Associated with Keratoconus by Xiao-Dan Hao (215742)

“…The relative mtDNA content of KC corneas was significantly lower than that of normal corneas (<i>P</i> = 9.19×10⁻²⁴), possibly due to decreased expression of the mitochondrial transcription factor A (<i>TFAM</i>) gene (<i>P</i> = 3.26×10⁻³). …”

MGAT1 knockdown decreases tumor migration, and invasion in prostate cancer cells. by Reza Beheshti Zavareh (308800)

siRNA-mediated knockdown of myosin-9 decreases reovirus infection and egress. by Isabel Fernández de Castro (22431012)

Repeat peptide stimulation decreases <i>in vivo</i> CTL expansion capacity. by Manzhi Zhao (9023381)

The 2lox Lsd1 variant shows decreased binding to known interactors. by Thomas B. Nicholson (406800)

“…(B) The relative coimmunoprecipitation of the Lsd1 binding partner CoREST was quantitated using ImageJ software. Data represent the mean +/− SD for two independent experiments. (C) Purification of endogenous Lsd1 complexes from MEF lines confirmed a decrease in Lsd1-CoREST interaction in cells expressing the mutant Lsd1. …”

Image_8_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a receptor 1(C5aR1) was significantly increased in skin lesions of both imiquimod (IMQ) and IL23-induced psoriatic mice and patients with psoriasis. …”

Image_2_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a receptor 1(C5aR1) was significantly increased in skin lesions of both imiquimod (IMQ) and IL23-induced psoriatic mice and patients with psoriasis. …”

Image_10_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a receptor 1(C5aR1) was significantly increased in skin lesions of both imiquimod (IMQ) and IL23-induced psoriatic mice and patients with psoriasis. …”

Image_9_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a receptor 1(C5aR1) was significantly increased in skin lesions of both imiquimod (IMQ) and IL23-induced psoriatic mice and patients with psoriasis. …”

Image_1_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a receptor 1(C5aR1) was significantly increased in skin lesions of both imiquimod (IMQ) and IL23-induced psoriatic mice and patients with psoriasis. …”

Image_3_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a receptor 1(C5aR1) was significantly increased in skin lesions of both imiquimod (IMQ) and IL23-induced psoriatic mice and patients with psoriasis. …”

Image_7_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a receptor 1(C5aR1) was significantly increased in skin lesions of both imiquimod (IMQ) and IL23-induced psoriatic mice and patients with psoriasis. …”