Cytidine-phosphate-guanosine oligodeoxynucleotides in combination with CD40 ligand decrease periodontal inflammation and alveolar bone loss in a TLR9-independent manner by Qian Zhao (217607)

“…Conclusions: These results indicated that CpG plus CD40L decreased periodontal inflammation and alveolar bone loss in a TLR9-independent manner in ligature-induced experimental periodontitis.…”

The major role of <i>sarA</i> in limiting <i>Staphylococcus aureus</i> extracellular protease production <i>in vitro</i> is correlated with decreased virulence in diverse clinical... by Mara J. Campbell (14579826)

Image_1_TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1.tif by Takahiko Akagi (13138338)

“…T79M is a known mutation responsible for TRAPS, whereas G87V is a TRAPS mutation that we have reported, and T90I is a variant of unknown significance. …”

Image_4_TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1.tif by Takahiko Akagi (13138338)

“…T79M is a known mutation responsible for TRAPS, whereas G87V is a TRAPS mutation that we have reported, and T90I is a variant of unknown significance. …”

Image_7_TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1.tif by Takahiko Akagi (13138338)

“…T79M is a known mutation responsible for TRAPS, whereas G87V is a TRAPS mutation that we have reported, and T90I is a variant of unknown significance. …”

Image_3_TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1.tif by Takahiko Akagi (13138338)

“…T79M is a known mutation responsible for TRAPS, whereas G87V is a TRAPS mutation that we have reported, and T90I is a variant of unknown significance. …”

Image_6_TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1.tif by Takahiko Akagi (13138338)

“…T79M is a known mutation responsible for TRAPS, whereas G87V is a TRAPS mutation that we have reported, and T90I is a variant of unknown significance. …”

Image_2_TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1.tif by Takahiko Akagi (13138338)

“…T79M is a known mutation responsible for TRAPS, whereas G87V is a TRAPS mutation that we have reported, and T90I is a variant of unknown significance. …”

Kcnk5b requires CaMKK for growth and SHH/<i>shha</i> expression. by Xiaowen Jiang (8291814)

Cardiac Development in Zebrafish and Human Embryonic Stem Cells Is Inhibited by Exposure to Tobacco Cigarettes and E-Cigarettes by Nathan J. Palpant (127912)

“…During cardiac differentiation of hESCs, tobacco smoke exposure results in a delayed transition through mesoderm. Both types of cigarettes decrease expression of cardiac transcription factors in cardiac progenitor cells, suggesting a persistent delay in differentiation. …”

Decrease of citric acid produced by <i>Aspergillus niger</i> through disruption of the gene encoding a putative mitochondrial citrate-oxoglutarate shuttle protein by Kohtaro Kirimura (414508)

Table_1_Unconventional Sea Surface Temperature Regime Around Japan in the 2000s–2010s: Potential Influences on Major Fisheries Resources.docx by Hiroshi Kuroda (769431)

“…In this paper, we review atmosphere and ocean conditions around Japan in the 2000s–2010s in terms of global climate, present an overview of potential impacts of decadal SST trends on five major commercial fisheries resources (walleye pollock, chum salmon, Japanese sardine, Japanese anchovy, and Japanese flying squid), and raise awareness that an unconventional regime can appear transiently during a state of global warming.…”

Medical School, Cardiovascular Surgery, and Education: how we do it in Brazil’s scenario? by Tiago Santos Ribeiro (12682417)

Patient selection and study design. by Shingo Hatakeyama (797994)

Decreased MCM2-6 in Drosophila S2 Cells Does Not Generate Significant DNA Damage or Cause a Marked Increase in Sensitivity to Replication Interference by Isabelle Crevel (119003)

“…<div><p>A reduction in the level of some MCM proteins in human cancer cells (MCM5 in U20S cells or MCM3 in Hela cells) causes a rapid increase in the level of DNA damage under normal conditions of cell proliferation and a loss of viability when the cells are subjected to replication interference. …”

Supplementary Material for: The Upregulation of a Novel Long Noncoding RNA AK097647 Promotes Enterovirus 71 Replication and Decreases IFN-λ1 Secretion by Chu M. (5689706)

Table1_Decreased circulating omega-3 fatty acids increase the risk of myocardial infarction: a two-sample Mendelian randomization study.docx by Wei Wang (17594)

Analysis of the Origin and Evolutionary History of HIV-1 CRF28_BF and CRF29_BF Reveals a Decreasing Prevalence in the AIDS Epidemic of Brazil by Natalia Ristic (228628)

“…The effective number of infections by these recombinants grew exponentially over a five-year period after their emergence, but then decreased toward the present following a logistic model of population growth. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”