Table1_Effect of botanical drugs in improving symptoms of hypertensive nephropathy: Analysis of real-world data, retrospective cohort, network, and experimental assessment.XLSX by Jia-Ming Huan (15185389)

“…</p><p>Results: A total of 14 botanical drugs and five symptom communities were obtained from real-world clinical data. …”

Image_1_Cardioprotecive Properties of Known Agents in Rat Ischemia-Reperfusion Model Under Clinically Relevant Conditions: Only the NAD Precursor Nicotinamide Riboside Reduces Infa... by Yang Xiao (146335)

“…., opiates, benzodiazepines, P2Y₁₂ antagonist, propofol) need to be identified in preclinical models.</p><p>Methods: Here, we examined the efficacy of promising cardioprotective compounds [fingolimod (Fingo), empagliflozin (Empa), melatonin (Mela) and nicotinamide riboside (NR)] administered i.v. as bolus before start ischemia. …”

Effects of siRNA on RET/PTC3 Junction Oncogene in Papillary Thyroid Carcinoma: From Molecular and Cellular Studies to Preclinical Investigations by Hafiz Muhammad Ali (554920)

“…Our aim is to demonstrate <i>in vitro</i> and <i>in vivo</i> molecular and cellular effects of siRNA on <i>RET/PTC3</i> knockdown for therapeutic application.First, we established a novel cell line stably expressing <i>RET/PTC3</i> junction oncogene, named RP3 which was found tumorigenic in nude mice compared to NIH/3T3 mouse fibroblasts. …”

Data_Sheet_1_Cardioprotecive Properties of Known Agents in Rat Ischemia-Reperfusion Model Under Clinically Relevant Conditions: Only the NAD Precursor Nicotinamide Riboside Reduces... by Yang Xiao (146335)

“…., opiates, benzodiazepines, P2Y₁₂ antagonist, propofol) need to be identified in preclinical models.</p><p>Methods: Here, we examined the efficacy of promising cardioprotective compounds [fingolimod (Fingo), empagliflozin (Empa), melatonin (Mela) and nicotinamide riboside (NR)] administered i.v. as bolus before start ischemia. …”

Insights into the mechanism regulating the differential expression of the P28-OMP outer membrane proteins in obligatory intracellular pathogen <i>Ehrlichia chaffeensis</i> by Nan Duan (4837896)

Presentation 1_Telehealth coaching in older adults, behavior change, and impacts of the COVID-19 pandemic: analyses from The Brain Health Champion Study.pdf by Brittany McFeeley (21104825)

“…Study 1.0 participants indicated a decrease in cognitive activities since the start of COVID-19 restrictions, whereas those in Study 2.0 reported an increase in cognitive activities.…”

Quantification of specific polyadenylated transcripts upon egg aging. by Anna Kosubek (239172)

“…The transcripts are named according to the corresponding gene symbols listed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0013532#pone.0013532.s004" target="_blank">Table S1</a> and were selected based on their >4-fold decrease in the microarray upon egg aging. …”

Schematic depicting the effects of truncation on consensus sequence position relative to array surface. by Nicholas O. Fischer (94124)

“…Truncations from both termini (5′[1]3′[1], 5′[2]3′[1], and 5′[1]3′[2]) result in a combination of both effects.…”

FIGURE 6 from Targeting <i>MALAT1</i> Augments Sensitivity to PARP Inhibition by Impairing Homologous Recombination in Prostate Cancer by Anjali Yadav (17117308)

“…The experiments were performed with <i>n</i> = 3 biologically independent samples; the data represents mean ± SEM. Extra sums of the square F-test was used to compute the statistical significance and compare the curves in A. …”

Hhat KD inhibits Hh-mediated juxtacrine/paracrine signaling. by Antonios D. Konitsiotis (532086)

“…<p>A. Hhat-#2 siRNA KD in A549 cells was assessed by qPCR 24–96 h after siRNA transfection showing 20–60% decrease in Hhat mRNA expression. …”

Clathrin-dependent Endocytosis is required for removal of Robo from the surface. by Rebecca K. Chance (2207449)

“…S2R+ cells treated with CM from cells expressing Slit (B) as opposed to empty vector (A) show a decrease in surface levels of Robo, quantified in (G) as a percent decrease in average pixel intensity value of processes in (B) as compared to (A). …”

PALS-25(Q293*) protein is not physically associated with PALS-22 protein. by Spencer S. Gang (13899687)

“…PALS-22::GFP::3xFLAG expressed from its endogenous promoter (<i>pals-22p</i>), intestinal promoter (<i>vha-6p</i>), or epidermal promoter (<i>dpy-7p</i>) captured by FLAG-IP interacts with endogenously expressed PALS-25(WT). A GFP::3xFLAG control expressed from the <i>spp-5p</i> promoter does not interact with PALS-25(WT). …”

GSH levels was increased in LM treated ARPE-19 cells, and enhanced oxygen consumption was related to <i>de novo</i> GSH synthesis. by Lin Zhao (92451)

“…Values are means ± SEM of three independent experiments. For A, B, C, D, E and G, statistical significance was established by one way ANOVA followed by the Tukey test. …”

The <em>PNPLA3</em> rs738409 G-Allele Associates with Reduced Fasting Serum Triglyceride and Serum Cholesterol in Danes with Impaired Glucose Regulation by Nikolaj Thure Krarup (154013)

“…In Inter99, we analyzed associations of rs738409 with components of the WHO-defined metabolic syndrome (<em>n</em> = 5,847) and traits related to metabolic disease (<em>n</em> = 5,663). …”

MicroRNA expression analyses in Nr2f1^–/– tissues. by David Y. Chiang (389033)

“…<p>(A) The expression of select miRNAs in the Nr2f1^–/– inner ear showing miR-140 and miR-181a were significantly down-regulated by 4.5-fold (P=0.004) and 1.7-fold (P=0.046), respectively, compared to the WT. …”

Functional Trait Strategies of Trees in Dry and Wet Tropical Forests Are Similar but Differ in Their Consequences for Succession by Madelon Lohbeck (731258)

“…We evaluated whether multivariate plant strategies changed during succession, by calculating a ‘Community-Weighted Mean’ plant strategy, based on species scores on the first two PCA-axes. …”

Immune mediator mRNA regulation. by Brian H. Bird (139289)

“…Deep blue reflects maximal fold-decrease detected (approximately −5 fold). Increasingly intensity of pale yellow to orange to red indicates range of fold-increase from +5 to a maximum of approximately +101 fold in IFNu at day 14 PI and in terminal cases. …”

Table_1_Blue Light Deprivation Produces Depression-Like Responses in Mongolian Gerbils.xlsx by Hong Hu (62885)

“…Furthermore, 5-HT in the serum and brain were decreased after BLD. …”

DataSheet_1_Thalamocortical Hyperconnectivity and Amygdala-Cortical Hypoconnectivity in Male Patients With Autism Spectrum Disorder.doc by Tetsuya Iidaka (162492)

“…</p><p>Methods: To overcome this issue, we analyzed multisite neuroimaging data from a large sample (n = 626) of male participants aged between 5 and 29 years (mean age = 13 years). …”

Testing the “Read-across hypothesis” by investigating the effects of ibuprofen on fish. by Alpa Patel (2937030)

“…Results showed that PGEM levels in fish exposed to 370 and 470 µg ibuprofen/L were significantly decreased compared to control fish, when mean plasma ibuprofen concentrations were 1.8 to 5.6-fold below the C_max. …”