Table 1_Case report: A severe case of zoledronate-associated diffuse orbital inflammation and uveitis in a patient with metastatic breast cancer.docx by Pushpinder Kanda (5125214)

“…We also performed a literature search to provide an up-to-date summary of cases with zoledronate-associated ocular inflammation.…”

Directional freezing for the cryopreservation of adherent mammalian cells on a substrate by Liat Bahari (4856704)

“…Experimental results show the highest post-thawing viability for directional ice growth at a speed of 30 μm/sec (equivalent to freezing rate of 3.8°C/min), followed by gradual cooling of the sample with decreasing rate of 0.5°C/min. Efficient cryopreservation of three widely used epithelial cell lines: IEC-18, HeLa, and Caco-2, provides proof-of-concept support for this new freezing protocol applied to adherent cells. …”

Reconciling a Kinetic Model for Dimerization of the EGFR Using Single-Molecule Tracking in Living Cells by Kiwook Kim (756439)

Inhibition of Glioblastoma Growth by the Thiadiazolidinone Compound TDZD-8 by Diana Aguilar-Morante (237970)

“…<div><h3>Background</h3><p>Thiadiazolidinones (TDZD) are small heterocyclic compounds first described as non-ATP competitive inhibitors of glycogen synthase kinase 3β (GSK-3β). In this study, we analyzed the effects of 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione (TDZD-8), on murine GL261 cells growth <em>in vitro</em> and on the growth of established intracerebral murine gliomas <em>in vivo</em>.…”

Examination of Spatial Distribution Patterns and Density Dependence in Three Forest Communities on Mt. Huangshan by Lei Xie (10927824)

“…Dominant species typically experienced density dependence at short distances (less than 5m). As the spatial scale increased, the probability of density dependence decreased. …”

The Non-Classical MAP Kinase ERK3 Controls T Cell Activation by Miriam Marquis (515431)

“…Moreover, ERK3 protein is phosphorylated and associates with MK5 in activated primary T cells. We show that ERK3-deficient T cells have a decreased proliferation rate and are impaired in cytokine secretion following <i>in vitro</i> stimulation with low dose of anti-CD3 antibodies. …”

Prevalence of cataract complications in patients with pseudoexfoliation syndrome in Northwestern Spain by Pedro Vazquez-Ferreiro (7396382)

“…Complications included any combination of posterior capsular rupture, vitreous loss, zonular dialysis, and nuclear or lens luxation. Results: We found a significant association between pseudoexfoliation syndrome and zonular dialysis (odds ratio [OR], 6.89; 95% CI, 2.27-20.93), intraoperative miosis (OR, 2.15; 95% CI, 1.10-4.22), and lens luxation >1.5 mm (OR, 9.49; 95% CI, 0.85-105.54). …”

Data_Sheet_1_Precipitation and soil nutrients determine the spatial variability of grassland productivity at large scales in China.pdf by Xianxian Wang (8107334)

“…Using 182 grassland samples established in 17 alpine meadows (AM) and 21 desert steppes (DS) in China, we show that NPP of AM was significantly higher than that of DS. …”

Image_1_Mutation in the 26S proteasome regulatory subunit rpn2 gene in Plasmodium falciparum confers resistance to artemisinin.pdf by Adriana F. Gonçalves (17937905)

“…Plasmids carrying a functional rpn2 interspecies chimeric gene with 5’ recombination region from P. falciparum and 3’ from P. chabaudi were constructed and transfected into Dd2 P. falciparum parasites.…”

Reconciling a Kinetic Model for Dimerization of the EGFR Using Single-Molecule Tracking in Living Cells by Kiwook Kim (756439)

Cellular automata to understand the prograding limit of deltaic tidal flat by Xuefei Mei (16541666)

“…During the 1989–2002 period, the advancing rate of the −5 m isobaths followed a Gaussian frequency distribution, in agreement with simulation results of cellular automata. …”

Prevalence of cataract complications in patients with pseudoexfoliation syndrome in Northwestern Spain by Pedro Vazquez-Ferreiro (7396382)

“…Complications included any combination of posterior capsular rupture, vitreous loss, zonular dialysis, and nuclear or lens luxation. Results: We found a significant association between pseudoexfoliation syndrome and zonular dialysis (odds ratio [OR], 6.89; 95% CI, 2.27-20.93), intraoperative miosis (OR, 2.15; 95% CI, 1.10-4.22), and lens luxation >1.5 mm (OR, 9.49; 95% CI, 0.85-105.54). …”

Functional Implications of Novel Human Acid Sphingomyelinase Splice Variants by Cosima Rhein (168205)

“…</p> <h3>Methodology/Principal Findings</h3><p>We identified three novel ASM splice variants in human cells, termed ASM-5, -6 and -7, which lack portions of the catalytic- and/or carboxy-terminal domains in comparison to full-length ASM-1. …”

Maximal long-term growth rate depends on the frequency of signals and stress. by Markus Arnoldini (141879)

“…The probability for a signal, , is 0.5. Cost parameters used are , for both plots.</p>…”

<b>Morin alleviates fructose-driven disturbance of podocyte mitochondrial energy metabolism by inhibiting AMPD activity to improve glomerular injury</b> by Luyi Huang (22583081)

“…<p dir="ltr">High consumption of fructose is a significant risk factor for glomerular podocyte injury. We reported a novel mechanism that high fructose increased the activity of adenosine 5’-monophosphate deaminase (AMPD) in the purine nucleotide cycle (PNC), which contributed to mitochondrial dysfunction and activated glycolysis in podocyte injury. …”

Data_Sheet_2_Rewiring of Gene Expression in Pseudomonas aeruginosa During Diauxic Growth Reveals an Indirect Regulation of the MexGHI-OpmD Efflux Pump by Hfq.pdf by Marlena Rozner (12911555)

“…As Hfq function is impeded by the RNA CrcZ upon relief of CCR, and Hfq is known to impact antibiotic susceptibility in P. aeruginosa, emphasis was laid on links between CCR and antibiotic susceptibility. To this end, we show that the mexGHI-opmD operon encoding an efflux pump for the antibiotic norfloxacin and the virulence factor 5-Methyl-phenazine is upregulated after alleviation of CCR, resulting in a decreased susceptibility to the antibiotic norfloxacin. …”

Image_2_Mutation in the 26S proteasome regulatory subunit rpn2 gene in Plasmodium falciparum confers resistance to artemisinin.pdf by Adriana F. Gonçalves (17937905)

“…Plasmids carrying a functional rpn2 interspecies chimeric gene with 5’ recombination region from P. falciparum and 3’ from P. chabaudi were constructed and transfected into Dd2 P. falciparum parasites.…”

Optimum temperature may be a misleading parameter in enzyme characterization and application by Vitor M. Almeida (4768668)

“…A search in the PubMed database for “optimum temperature” and “enzymes” yielded more than 1,700 manuscripts reporting this parameter over the last five years. Here, we show that the optimum temperature is not a constant. …”

Application of Multichannel Collagen Gels in Construction of Epithelial Lumen-like Engineered Tissues by Kazuya Furusawa (1569568)

Glasslike Membrane Protein Diffusion in a Crowded Membrane by Ignacio Munguira (1434316)