Assessment of in vitro and in vivo effect of Quercetin 3-Glucoside, Oxyresveratrol and Quercetin O-Hexoside against Leishmania tropica by Kashif Iqbal (6504587)

“…The Quercetin 3-Glucoside shows mean inhibition of extracellular promastigotes after 48 hours at 50, 100, 150, 200 µg/mL were 91.02 ± 0.12, 94.50 ± 0.07, 96.15 ± 0.17 and 97.01 ± 0.08 % respectively. …”

Image_3_Human Wharton's Jelly Stem Cell (hWJSC) Extracts Inhibit Ovarian Cancer Cell Lines OVCAR3 and SKOV3 in vitro by Inducing Cell Cycle Arrest and Apoptosis.TIF by Gauthaman Kalamegam (6059681)

“…TS of OVCAR3 and SKOV3 also showed the presence of few ovarian cancer stem cells (CSCs) in minimal numbers following treatment with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h. Real-time gene expression analysis of OVCAR3 and SKOV3 treated with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h demonstrated decreased expression of cell cycle regulatory genes (cyclin A2, Cyclin E1), prostaglandin receptor signaling genes (EP2, EP4) and the pro-inflmmatory genes (IL-6, TNF-α) compared to untreated controls. …”

Image_2_Human Wharton's Jelly Stem Cell (hWJSC) Extracts Inhibit Ovarian Cancer Cell Lines OVCAR3 and SKOV3 in vitro by Inducing Cell Cycle Arrest and Apoptosis.TIF by Gauthaman Kalamegam (6059681)

“…TS of OVCAR3 and SKOV3 also showed the presence of few ovarian cancer stem cells (CSCs) in minimal numbers following treatment with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h. Real-time gene expression analysis of OVCAR3 and SKOV3 treated with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h demonstrated decreased expression of cell cycle regulatory genes (cyclin A2, Cyclin E1), prostaglandin receptor signaling genes (EP2, EP4) and the pro-inflmmatory genes (IL-6, TNF-α) compared to untreated controls. …”

Image_1_Human Wharton's Jelly Stem Cell (hWJSC) Extracts Inhibit Ovarian Cancer Cell Lines OVCAR3 and SKOV3 in vitro by Inducing Cell Cycle Arrest and Apoptosis.TIF by Gauthaman Kalamegam (6059681)

“…TS of OVCAR3 and SKOV3 also showed the presence of few ovarian cancer stem cells (CSCs) in minimal numbers following treatment with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h. Real-time gene expression analysis of OVCAR3 and SKOV3 treated with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h demonstrated decreased expression of cell cycle regulatory genes (cyclin A2, Cyclin E1), prostaglandin receptor signaling genes (EP2, EP4) and the pro-inflmmatory genes (IL-6, TNF-α) compared to untreated controls. …”

Effects and mechanisms of water-soluble Semen cassiae polysaccharide on retinitis pigmentosa in rats by Suiqin HE (7029191)

“…On the sixth day, the model, and 50, 100 and 200 mg/kg SCP groups were treated with N-nitroso-N-methylurea (MNU). …”

Effects and mechanisms of water-soluble Semen cassiae polysaccharide on retinitis pigmentosa in rats by Suiqin HE (7029191)

“…On the sixth day, the model, and 50, 100 and 200 mg/kg SCP groups were treated with N-nitroso-N-methylurea (MNU). …”

Genome-wide association study of Streptococcus pneumoniae identifies disease-associated genetic variation by Shimin Yang (17308492)

“…First, a univariate LMM was fitted to initially screen infection-associated k-mers by the Pyseer (v1.3.10) Second, we used multiple methods (Scoary, LASSO and VSURF) to minimize false-positive associations and identify consensus infection-associated k-mers.The importance of k-mers was ranked by the mean decrease in impurity (Mean Decrease Gini, MDG), which is a measure of the predictor’s contribution to the correct sample classification.…”

Mechanical and Microstructural Properties of Redispersible Polymer-Gypsum Composites by Carlos Eduardo Marmorato Gomes (6675479)

“…The composites were prepared using a polymer concentration of 5% and 10%, and water/gypsum ratio of 0.6. The addition of the polymer decreased the structural robustness and change in the microstructure. …”

Data_Sheet_1_Two-year follow-up of the COVID-19 pandemic in Mexico.PDF by Antonio Loza (5319467)

“…Factors such as the decrease in the severity of the SARS-CoV2 variants, changes in symptomatology, and advances in the management of patients, vaccination, and treatments influenced the decrease in mortality and hospitalizations.…”

Image_1_Xanthine Oxidoreductase Is Involved in Chondrocyte Mineralization and Expressed in Osteoarthritic Damaged Cartilage.jpg by Sonia Nasi (383541)

“…We showed both in murine primary chondrocyte and chondrogenic ATDC5 cells, that mineralization was inhibited by two different XOR inhibitors, febuxostat and allopurinol. …”

Image_2_Xanthine Oxidoreductase Is Involved in Chondrocyte Mineralization and Expressed in Osteoarthritic Damaged Cartilage.JPEG by Sonia Nasi (383541)

“…We showed both in murine primary chondrocyte and chondrogenic ATDC5 cells, that mineralization was inhibited by two different XOR inhibitors, febuxostat and allopurinol. …”

Image_3_Xanthine Oxidoreductase Is Involved in Chondrocyte Mineralization and Expressed in Osteoarthritic Damaged Cartilage.JPEG by Sonia Nasi (383541)

“…We showed both in murine primary chondrocyte and chondrogenic ATDC5 cells, that mineralization was inhibited by two different XOR inhibitors, febuxostat and allopurinol. …”

Image_4_Xanthine Oxidoreductase Is Involved in Chondrocyte Mineralization and Expressed in Osteoarthritic Damaged Cartilage.JPEG by Sonia Nasi (383541)

“…We showed both in murine primary chondrocyte and chondrogenic ATDC5 cells, that mineralization was inhibited by two different XOR inhibitors, febuxostat and allopurinol. …”

EFFECTS OF AEROBIC EXERCISE ON BODY MORPHOLOGY IN OBESE UNIVERSITY STUDENTS by Ma Jin (12651607)

Data_Sheet_1_Tranexamic Acid for Acute Spontaneous Intracerebral Hemorrhage: A Meta-Analysis of Randomized Controlled Trials.docx by Yu Guo (102701)

“…</p><p>Results: We identified seven studies (representing five RCTs) involving 2,650 participants. …”

Data_Sheet_1_The Responses of Germ-Free Zebrafish (Danio rerio) to Varying Bacterial Concentrations, Colonization Time Points, and Exposure Duration.docx by Fang Tan (353838)

“…Therefore, we mono-associated GF zebrafish with Escherichia coli DH5α or Bacillus subtilis WB800N at concentrations ranging from 10² to 10⁷ CFU/ml either at 3 day post fertilization (dpf) or 5 dpf for 24 or 48 h. …”

DataSheet_1_Impacts of coral bleaching on reef fish abundance, biomass and assemblage structure at remote Aldabra Atoll, Seychelles: insights from two survey methods.zip by Anna Koester (11805572)

“…In contrast, extended fish surveys in 2015 and 2020 showed a 55–60% reduction in overall abundance on shallow and deep reefs, and a 69% reduction in biomass on shallow reefs, with decreases in biomass occurring in all functional groups. …”

Data_Sheet_6_Loss of KCC2 in GABAergic Neurons Causes Seizures and an Imbalance of Cortical Interneurons.PDF by Kirill Zavalin (12247937)

“…Nonetheless, the mice had early seizures, failure to thrive, and premature death in the second and third weeks of life. At this age, we found an underlying change in IN distribution, including an excess number of somatostatin neurons in layer 5 and a decrease in parvalbumin-expressing neurons in layer 2/3 and layer 6. …”

Video_1_Loss of KCC2 in GABAergic Neurons Causes Seizures and an Imbalance of Cortical Interneurons.MP4 by Kirill Zavalin (12247937)

“…Nonetheless, the mice had early seizures, failure to thrive, and premature death in the second and third weeks of life. At this age, we found an underlying change in IN distribution, including an excess number of somatostatin neurons in layer 5 and a decrease in parvalbumin-expressing neurons in layer 2/3 and layer 6. …”

Video_2_Loss of KCC2 in GABAergic Neurons Causes Seizures and an Imbalance of Cortical Interneurons.MP4 by Kirill Zavalin (12247937)

“…Nonetheless, the mice had early seizures, failure to thrive, and premature death in the second and third weeks of life. At this age, we found an underlying change in IN distribution, including an excess number of somatostatin neurons in layer 5 and a decrease in parvalbumin-expressing neurons in layer 2/3 and layer 6. …”