Image_1_Silencing of miR-150-5p Ameliorates Diabetic Nephropathy by Targeting SIRT1/p53/AMPK Pathway.TIF by Wenmin Dong (10578710)

“…Consequently, we investigated the effect and mechanism of action of miR-150-5p in DN in vitro and in vivo. …”

Image5_Elabela Attenuates the TGF-β1-Induced Epithelial-Mesenchymal Transition of Peritoneal Mesothelial Cells in Patients Receiving Peritoneal Dialysis.tif by Shunyun Xie (12898211)

“…Compared with those in patients with stage 5 chronic kidney disease who are not on dialysis, serum ELA levels in patients on PD increased with the improvement of residual renal function at PD duration <36 months and decreased to pre-dialysis levels at PD duration ≥36 months, suggesting that dialysis duration is the main risk factor affecting serum ELA levels in patients on PD. …”

Table 5_CX3CR1 upregulation modulates microglial activation and preserves synapses in the hippocampus and frontal cortex of middle-aged mice.xlsx by Jinfeng Liu (32678)

Image_1_Angiogenesis Inhibition by a Short 13 Amino Acid Peptide Sequence of Tetrastatin, the α4(IV) NC1 Domain of Collagen IV.TIF by Alexia Vautrin-Glabik (9227216)

“…The inhibitory activity was located in a 13 amino acid sequence named QS-13. In the present paper, we demonstrate that QS-13 decreases VEGF-induced-angiogenesis in vivo using the Matrigel plug model. …”

Image_2_Angiogenesis Inhibition by a Short 13 Amino Acid Peptide Sequence of Tetrastatin, the α4(IV) NC1 Domain of Collagen IV.TIF by Alexia Vautrin-Glabik (9227216)

“…The inhibitory activity was located in a 13 amino acid sequence named QS-13. In the present paper, we demonstrate that QS-13 decreases VEGF-induced-angiogenesis in vivo using the Matrigel plug model. …”

Image_5_A high interferon gamma signature of CD8+ T cells predicts response to neoadjuvant immunotherapy plus chemotherapy in gastric cancer.tif by Sen Li (155994)

Table_1_Altered Expression of ACE2 and Co-receptors of SARS-CoV-2 in the Gut Mucosa of the SIV Model of HIV/AIDS.XLSX by Shuang Hu (182425)

“…We investigated changes in the expression of ACE2 and other SARS-CoV-2 receptors and related pathways in virally inflamed gut by using the SIV infected rhesus macaque model of HIV/AIDS. …”

Efficacy of 3-day versus 5-day aprepitant regimens for long-delayed chemotherapy-induced nausea and vomiting in patients receiving cisplatin-based chemotherapy by Toshinobu Hayashi (17456110)

“…</p> <p>A 5-day regimen triplet antiemetic prophylaxis with APR decreased long-delayed vomiting compared with a 3-day regimen in patients receiving CDDP-based chemotherapy. …”

Table_5_A Large-Scale Genome-Based Survey of Acidophilic Bacteria Suggests That Genome Streamlining Is an Adaption for Life at Low pH.XLSX by Diego Cortez (239207)

Image_5_Aging-Dependent Altered Transcriptional Programs Underlie Activity Impairments in Human C9orf72-Mutant Motor Neurons.tiff by Daniel Sommer (133337)

Table5_Comparative transcriptome analysis reveals key candidate genes mediating ovarian development in Spodoptera frugiperda fed on two host plants.xlsx by Renwen Zheng (14118510)

Image_5_Loss of Deacetylation Enzymes Hdac6 and Sirt2 Promotes Acetylation of Cytoplasmic Tubulin, but Suppresses Axonemal Acetylation in Zebrafish Cilia.TIF by Paweł K. Łysyganicz (11041419)

DataSheet_1_PACAP–PAC1 Signaling Regulates Serotonin 2A Receptor Internalization.pdf by Atsuko Hayata-Takano (525514)

“…Here, we examined whether PACAP modulates 5-HT_2A signaling by addressing cellular protein localization. …”

Table_5_Patients With Common Variable Immunodeficiency (CVID) Show Higher Gut Bacterial Diversity and Levels of Low-Abundance Genes Than the Healthy Housemates.xlsx by Juraj Bosák (495467)

Loop in the IB domain drives ParM monomer opening. by Natalie Ng (6560246)

“…Two simulations (ParM-ATP-2,3) consistently exhibited opening angles of ~102° after 50 ns and maintained that value, whereas in the other simulation (ParM-ATP-1), the opening angle increased beyond 105° after 100 ns and then eventually decreased to ~103° in the last 20 ns of the 200-ns simulation (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006683#pcbi.1006683.s004" target="_blank">S4A Fig</a>). …”

Table_1_Anti-nociceptive and Anti-inflammatory Activities of Asparacosin A Involve Selective Cyclooxygenase 2 and Inflammatory Cytokines Inhibition: An in-vitro, in-vivo, and in-si... by Nasiara Karim (6085445)

“…Asparacosin A also inhibited the human recombinant COX-2 enzyme and caused a dose-dependent decrease in the levels of TNF-α, IL-1β, and PGE2 in the carrageenan-induced paws. …”

DataSheet1_Refinement of SARS-CoV-2 envelope protein structure in a native-like environment by molecular dynamics simulations.docx by Rui Yang (293531)

“…We also demonstrated the utility of this structure to develop anti-SARS-CoV-2 drugs by docking a library of FDA-approved, investigational, and experimental drugs to the refined E protein structure, identifying 20 potential channel blockers. …”

DataSheet1_Hermansky-Pudlak Syndrome: Identification of Novel Variants in the Genes HPS3, HPS5, and DTNBP1 (HPS-7).docx by Doris Boeckelmann (11966570)

“…For IP1 with the compound heterozygous variants in HPS3 a specialized ophthalmological examination showed ocular albinism. HPS3 and HPS5 encode subunits of the BLOC-2 complex and patients with HPS-3 or HPS-5 are known to present with variable/mild hypopigmentation.…”

Data_Sheet_5_Proerythroblast Cells of Diamond-Blackfan Anemia Patients With RPS19 and CECR1 Mutations Have Similar Transcriptomic Signature.PDF by Beren Karaosmanoglu (10957938)

DataSheet_1_Omicron Variant of SARS-CoV-2 Virus: In Silico Evaluation of the Possible Impact on People Affected by Diabetes Mellitus.pdf by Davide Bassani (11170376)

“…Given the evidenced features of this variant, we aimed to investigate with a computational approach the characteristics of Omicron SARS-CoV-2 with respect to its binding to human ACE-2 receptor, in a particular population, namely people affected by diabetes mellitus, at risk for unfavorable outcomes of the COVID-19. …”