Video7_Rheological comparison between control and Dupuytren fibroblasts when plated in circular micropatterns using atomic force microscopy.AVI by Sandra Pérez-Domínguez (14155437)

Image 2_One-year post lockdown trajectories of mental health and impact of COVID-19 lockdown-related factors.jpeg by Mathilde Mongeau (20864315)

“…</p>Methods<p>In this study, we examined longitudinal trajectories of mental health during the initial French lockdown period and up to one-year post-lockdown, among a representative sample of French adults aged over 50. …”

An early Env engineered to have weak, medium, or tight binding to CD4 becomes progressively more promiscuous in its use of primate CD4 receptors. by Cody J. Warren (563898)

“…Error bars are not plotted in instances in which the size of the error bar is less than the symbol size. IC₅₀ values are listed on each panel, for which the mean and SD values reflect the variation of the IC₅₀ calculations from two independent experiments. …”

DataSheet_3_Trypanosoma cruzi Induces B Cells That Regulate the CD4+ T Cell Response.pdf by Martín Somoza (11906585)

DataSheet_1_Trypanosoma cruzi Induces B Cells That Regulate the CD4+ T Cell Response.pdf by Martín Somoza (11906585)

DataSheet_2_Trypanosoma cruzi Induces B Cells That Regulate the CD4+ T Cell Response.pdf by Martín Somoza (11906585)

Source data file. by Laura Mora-Bitria (20477525)

“…We studied Type 1 diabetes (T1D) as a paradigmatic example of autoimmunity. …”

Supporting data file. by Laura Mora-Bitria (20477525)

“…We studied Type 1 diabetes (T1D) as a paradigmatic example of autoimmunity. …”

File contains the zipped set of figures for this paper in PNG format. by Piotr Borkowski (15195012)

“…Top: all eigenvectors. Bottom: 50 eigenvectors with the lowest eigenvalue. S4_5_Fig.png: S4_5_FigButtom.png: Relative error among the elements of eigenvector constituting its halfmass (standard error divided by the mean). …”

Data_Sheet_1_Foliar Aphid Herbivory Alters the Tomato Rhizosphere Microbiome, but Initial Soil Community Determines the Legacy Effects.docx by Elizabeth French (10538804)

“…High aphid infestation impacted rhizosphere bacterial diversity in a soil-dependent manner, ranging from a 22% decrease to a 21% increase relative to uninfested plants and explained 6–7% of community composition differences in two of three soils. …”

DataSheet1_Restoring Nature at Lower Food Production Costs.docx by Yiorgos Vittis (10870491)

“…Although production inputs per unit of output increase at local scales, a reduction of cultivated land of 50% overcompensates the slightly higher field-scale costs enabling improved overall cost-effectiveness. …”

Elevated internalization and cytotoxicity of polydispersed single-walled carbon nanotubes in activated B cells can be basis for preferential depletion of activated B cells <i>in vi... by Taru S. Dutt (6868505)

Table_1_Application of lymphoplasmapheresis in the treatment of severe myasthenia gravis.DOCX by Weiwei Duan (5940539)

“…The overall safety of LPE was good, and no serious adverse reactions occurred. After treatment, the mean QMGS of patients decreased significantly, from 23.40 ± 4.25 points before treatment to 17.93 ± 5.61 points after treatment, a decrease of 5.47 ± 4.16 points. 75.6% of patients experienced remission of clinical symptoms. …”

Quantification of <i>in vivo</i> silica nanoparticle clearance. by Pascal Detampel (7444607)

“…<b>D:</b> Whole organ imaging. Overlay of a white light image of the organs and a heat map-display of the fluorescence in liver (top), spleen (middle), and kidney (bottom) 24 h after instillation of Ø 50 nm Cy-7-labelled silica particles into the lung (right). …”

DataSheet_1_Safety, tolerability, pharmacokinetics and pharmacokinetic-pharmacodynamic modeling of cetagliptin in patients with type 2 diabetes mellitus.docx by Chen Zhou (466781)

“…Compared with placebo group, plasma active GLP-1 AUEC_0-24h increased by 2.20- and 3.36-fold in the 50 mg and 100 mg cetagliptin groups. A decrease of plasma glucose and increase of insulin and C-peptide were observed following OGTT in cetagliptin groups. …”

Analysis of NIST Monoclonal Antibody Reference Material Glycosylation Using the LC–MS/MS-Based Glycoproteomic Approach by Jingfu Zhao (3113421)

“…Glycosylation is an essential critical quality attribute (CQA) due to the influence that glycoforms have on the safety, efficacy, and pharmacokinetics/pharmacodynamics (PK/PD) of biotherapeutics. Here, we applied an LC–MS/MS-based glycoproteomics approach to characterize Fc glycans of an NISTmAb reference material (RM) 8671 (sample B) and a β-1,4-galactosidase-treated NISTmAb (sample A). …”

Depressive symptoms are associated with blunted reward learning in social contexts by Lou Safra (553574)

“…<div><p>Depression is characterized by a marked decrease in social interactions and blunted sensitivity to rewards. …”

PLK2i treatment of OHSCs does not affect generation of pS129 positive aggregates, but reduces the nuclear pS129 intensity. by Sara Elfarrash (8159490)

“…Scale bars = 20 μm. b) Quantification of the amount of aggregation (aggregate area normalized to tissue area), defined by MJF-14 staining (p-value = 0.09). c-d) Quantification of the mean fluorescence intensity of α-syn aggregates detected with MJF-14 (c, p-value = 0.712) and aggregate-specific pS129 that overlaps with MJF-14 (d, p-value = 0.214). e) Quantification of nuclear (non-aggregate related) pS129, illustrating a significant decrease in mean fluorescence intensity following PLK2i-treatment (p-value = 0.0087). f) Relative ratio of aggregate-specific pS129/nuclear pS129 in PFF-injected slices shows an increase of ratio of the signals of aggregates/background following PLK2i treatment, due to reduction of the non-aggregate-related nuclear pS129-signal (p-value = 0.009). …”

Table 1_Growth dynamics, reproductive biology, and nutritional profiling of the freshwater mussel Lamellidens marginalis (Lamarck, 1819): implications for wild stock conservation a... by Md. Mostafizur Rahman Mondol (22045478)

“…This species displayed a continuous reproductive ability year-round, with a peak in July–August at 32.30−34.50°C. …”

Weight gain was associated with worsening glycemia and cardiovascular and kidney outcomes in type 2 diabetes patients independent of diabetes medication in the GRADE Randomized Con... by Deborah J. Wexler (492527)

“…<p dir="ltr">Objective: Weight gain with glucose-lowering medications may interfere with effective type 2 diabetes (T2D) management. We evaluated weight change and the effect of weight gain on outcomes over 5 years on four diabetes medications.…”