Solvent Entrapment of BI 763963 by Solid Solution Formation by Samruddhi Patil (11523791)

“…Two binary T-w phase diagrams were constructed showing the outline of the solidus and liquidus, where EtOH and IPA are present in the solid phase of BI 763963 at 0.54 and 1.5 wt %, respectively, at equilibrium. Importantly, the solvent solubility of BI 763963 was found to be dependent on the residual solvent level in the solid phase and in the case of EtOH increased by almost 50% at just 1.1 wt % EtOH entrapment. …”

Data Sheet 1_Validation of an MPS-based intestinal cell culture model for the evaluation of drug-induced toxicity.docx by Stefanie Hoffmann (3756733)

“…Overall, from the 23 tested compounds, 15 showed the expected outcome, i.e., the compound led to a decrease of the TEER for the positive control compounds, or the TEER value remained stable after treatment with non-GI-toxic compounds.…”

H2-K^b overexpression decreases NSPC proliferation and impairs adult hippocampal neurogenesis. by Karin Lin (11037548)

Δ<i>gra72</i> parasites form bubble vacuoles with decreased PVM permeability to small molecules. by Tatiana C. Paredes-Santos (16699433)

HAstV-8 (D471S, N512D) spike has decreased or no binding to FcRn compared to wild-type HAstV-8 spike. by Catalina Aguilera-Flores (21743843)

Changes in TEER and permeability of EA.hy926 cells exposed to EVs or pellets from infected or uninfected macrophages. by Myriam Lucia Velandia-Romero (8259726)

“…The EA.hy926 cells seeded on transwell® inserts showed a TEER of 25 Ω/Cm² at time 0. The controls: non-exposed cells (NEC), cells exposed to IP vesicles from uninfected U937 macrophages <i>(EV (-))</i> or EVs from U937 infected macrophages and irradiated UV (<i>EVs (+)</i>_<i>UV</i><i>)</i>, presented an increase in the TEER between 2 and 9 Ω/cm² in the course of the experiments, while the EA.hy926 cells infected with DENV-2 (MOI 0.2) (IC) reach 12 Ω/cm² at 24 h p.e. …”

Proviral load in blood was decreased in HTLV-1 infected CD133+ Hu-mice when vCTCF-BS was deleted. by Ancy Joseph (5634794)

Spatial training decreases the association between Ndfip1 and Nedd4 and decreases endogenous Beclin 1 ubiquitination in the hippocampus. by Wei-Lun Hsu (1756123)

Decreasing patterns of P_WT scores in 6 conditions with individual values (0.05, 0.1, 0.2, 0.3, 0.4, and 0.5). by In Seok Yang (4261207)

The cytoplasmic leaflet of the TGN in the Neo1p-depleted <i>cfs1</i>Δ <i>erd1</i>Δ mutant contains PS and decreased level of PI4P. by Mamoru Miyasaka (9187916)

ERK signaling and expression of β-arrestin2 in Ang II–induced mouse AAA models as well as in WT or Klf5^−/− VSMCs. by Dong Ma (584680)

Echocardiographic measurements in WT and AMPKα2-/- mice following transverse aortic constriction. by Anne Garnier (130125)

Subjects:

RMSD graphs for the backbone of WT PARG1, I845V and T622M mutants. by Zen Kouchi (14898435)

Video_1_Two-Stage Interpretation of Changes in TEER of Intestinal Epithelial Layers Protected by Adhering Bifidobacteria During E. coli Challenges.AVI by Lu Yuan (125712)

“…Thus, single-time TEER is interpretable in two ways, depending whether increasing to or decreasing from its maximum. …”

The decrease in blood flow disrupts CV pruning. by Lin Wen (557398)

Cardiac function assessed by echocardiography in Ang II–infused young (3 months) or old (18 months) WT and smcKlf5^−/− mice. by Dong Ma (584680)

The GluN2B-C456Y mutation decreases recombinant NMDAR currents and alters receptor properties. by Wangyong Shin (6793040)

“…<i>n</i> = 73 oocytes for WT (5.70 ± 0.61 μA) and 59 oocytes for C456Y (0.039 ± 0.004 μA), ***<i>P</i> < 0.001, Mann-Whitney. …”

Data_Sheet_1_Two-Stage Interpretation of Changes in TEER of Intestinal Epithelial Layers Protected by Adhering Bifidobacteria During E. coli Challenges.DOCX by Lu Yuan (125712)

“…Thus, single-time TEER is interpretable in two ways, depending whether increasing to or decreasing from its maximum. …”

Population dynamics of <i>Killer-Rescue</i>/Cargo, <i>ClvR</i> and split^50cM <i>ClvR</i> V2. by Georg Oberhofer (3401438)

Metformin decreases CRC-like organoids viability to the same extent as current chemotherapy without significant effects on WT organoids. by Silvia Cruz-Gil (7037249)