Ifit2 deficiency results in decreased neuroinflammation upon RSA59 infection. by Jayasri Das Sarma (652473)

Increased endodiastolic volume and decreased ejection fraction in GJB4-deficient zebrafish. by Ryuji Okamoto (614374)

WT1 siRNA decreases proliferation, pAKT, and Bcl2 expression. by Ayana E. Morales (17756335)

“…<b>C.</b> RT-qPCR of WT1, p<0.05(*), vFLIP(ns), LANA, p<0.0001(****), K8.1, p<0.0001(****), and BCL2 p<0.05(*) in the setting of WT1 knockdown in ISLK BAC-16 with WT1 siRNA in comparison to a control siRNA using two-sided, unpaired student’s t-tests. …”

Gating properties of <i>CACNA1I</i> variants with pooled WT data. by Yousra El Ghaleb (22075892)

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HDM-specific IgE levels decreased in response to TSLPR ablation in chronic model of asthma mice. by Latifa Koussih (326043)

Spatial training decreases the association between Ndfip1 and Nedd4 and decreases endogenous Beclin 1 ubiquitination in the hippocampus. by Wei-Lun Hsu (1756123)

“…The Ndfip1 expression level is decreased in both the IP product and the lysate in trained rats. …”

Spatial training decreases endogenous PTEN ubiquitination and <i>Pten</i> cKO mice show impaired spatial learning and memory. by Wei-Lun Hsu (1756123)

“…Their CA1 tissue was subjected to western blot determination of PTEN expression, and the PTEN expression level is increased in trained rats (t_1,10 = 8.59, <i>p</i> < 0.001). N = 6 each group. <b>(D)</b> The <i>Pten loxp</i> mice (that received lenti-GFP vector transduction) and <i>Pten</i> cKO mice (that received lenti-GFP-2A-NLS-Cre vector transduction) were subjected to water maze learning two weeks after lentivirus transduction. …”

WT data of set A398E/V and set M1425V/I pooled for better comparison. by Yousra El Ghaleb (22075892)

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The effect of R55H, D149E, and G59R on the structure of RAD52. by Abdulaziz B. Hamid (13804692)

Comparison of the Th2 cytokine expression level after treatment with KA/E2 in WT and TLR2 KO mice. by Mi-Kyung Park (56053)

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ERK signaling and expression of β-arrestin2 in Ang II–induced mouse AAA models as well as in WT or Klf5^−/− VSMCs. by Dong Ma (584680)

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Young (3 months) or old (18 months) WT and smcKlf5^−/− mice were infused with Ang II for 28 days. by Dong Ma (584680)

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RNF5 loss decreases PEL xenograft tumor growth and cell cycle gene expression. by Xiaojuan Li (351842)

Cardiac function assessed by echocardiography in Ang II–infused young (3 months) or old (18 months) WT and smcKlf5^−/− mice. by Dong Ma (584680)

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Diabetic wounds show increased amounts of vessel leakage and decreased pericyte coverage. by Uzoagu A. Okonkwo (8754933)

Fibγ^Δ5 mice display decreased survival following <i>S. aureus</i> peritonitis. by Oscar Negrón (11965511)

Representative TUNEL- and DAPI-stained sections from the abdominal aortas of young and old WT and smcKlf5^−/− mice following 28 days of Ang II infusion. by Dong Ma (584680)

Subjects:

Brain and liver GCase activity are significantly decreased in heterozygous <i>GBA1</i> D409V KI mice, with varying differences in glucosphingolipid lipids in brain and liver. by Nicole K. Polinski (10947787)

“…<p>(A-B) GCase, (C-D) gluocosylceramide (GlcCer), and (E-F) glucosylsphingosine (GlcSph) levels measured in whole brain homogenate and liver homogenate of C57Bl/6 wild type (WT) and <i>GBA1</i> D409V KI heterozygous (HET) mice at 5 months of age (n = 10/age). …”

GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age. by Nicole K. Polinski (10947787)

“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”

LuxR G37V has decreased DNA-binding activity. by Chelsea A. Simpson (9579303)