Conformational fingerprint of mutant ACE. by Sergei M. Danilov (118956)

“…Data are expressed as a ratio of ACE activity precipitated by different mAbs from mutant ACE to that of WT ACE. Data presented as a mean of 3–4 independent determinations in duplicate. * p<0.05 indicates ratio shown is significantly different from 1. mAbs showing significant changes in binding compared to WT are colored (red: increase >20%, yellow: decrease >20%).…”

Synaptic efficacy is reduced during UP states. by Brendon O. Watson (268774)

“…Every neuron examined (n = 16) showed a decrease in depolarization from baseline (population mean was a 103.3% decrease, standard deviation 14.1%). …”

Slug regulates mammary epithelial cell differentiation pathways. by Mayssa Nassour (109073)

“…D. PCNA1 and CK5 were visualized by double-immunofluorescence including DAPI co-staining on paraffin sections from wild-type (WT) or Slug-deficient mouse (KO) ducts, as indicated. …”

Arf4 overexpression rescues spine loss in apoE4-expressing primary neurons. by Sachi Jain (108277)

“…Neurons were transfected with FUGW2 plasmid alone (for visualization of spines) or with FUGW2 plus Arf4-HA-WT at DIV5 and analyzed at DIV14. Lower (<i>C−H</i>) and higher (<i>C′−H′</i>) magnification images are shown. …”

Increased Muscle Damage in HIF-1α KOs Following Repeated Exercise by Steven D Mason (70755)

“…</p> <p>(D) Number of PCNA-positive nuclei per square millimeter in gastrocnemius muscles of WT mice (<i>n</i> = 5) and HIF-1α KOs (<i>n</i> = 7) that ran repeatedly for 4 d. …”

Mouse phenotyping identified 200 BMD genes. by Anna L. Swan (9922965)

“…(C) Percentage change in BMD compared to wt animals. In both male (blue bars) and female (pink bars) mice, most BMD genes reduced BMD between 5% and 10%. …”

Table_1_Increasing Number of Individuals Receiving Hepatitis B nucleos(t)ide Analogs Therapy in Germany, 2008–2019.DOCX by Anna Maisa (263303)

“…Contrary to guideline recommendation, adefovir was still prescribed after 2011 for 1–5% of patients albeit with decreasing tendency. Prescriptions per 100,000 inhabitants were highest in Berlin and Hamburg.…”

Table_1_Increasing Number of Individuals Receiving Hepatitis B nucleos(t)ide Analogs Therapy in Germany, 2008–2019.DOCX by Anna Maisa (263303)

“…Contrary to guideline recommendation, adefovir was still prescribed after 2011 for 1–5% of patients albeit with decreasing tendency. Prescriptions per 100,000 inhabitants were highest in Berlin and Hamburg.…”

Low Socioeconomic Status Is Associated with Prolonged Times to Assessment and Treatment, Sepsis and Infectious Death in Pediatric Fever in El Salvador by Ronald Gavidia (141156)

“…Providing additional education to high-risk families and staying at a nearby guest house during periods of neutropenia may decrease sepsis and infectious mortality.…”

fon-2021-1437_suppl_data by Charles Peterfy (674120)

“…From baseline to last visit, 94% of patients (29/31) showed a decrease in tumor size (median change: −60% [RECIST], −66% [m-RECIST], −79% [TVS]). …”

Updated Emission Factors from Diffuse Combustion Sources in Sub-Saharan Africa and Their Effect on Regional Emission Estimates by David J. Pfotenhauer (6708245)

“…Large differences are calculated for all updated source emissions, showing a 96% increase in OC and 78% decrease in EC compared to prior estimates for Ghana’s emissions. …”

Progress toward implementing the Swiss Hepatitis Strategy: Is HCV elimination possible by 2030? by Beat Müllhaupt (416436)

“…Given the current standard of care, total viremic infections are expected to decline by 45%, while cases of decompensated cirrhosis, hepatocellular carcinoma, and liver-related deaths will decrease by 20%. If treatment and diagnosis efforts were to cease in 2018, late stage HCV-related morbidity and mortality would increase by 90–100% by 2030. …”

X-ChIP based affinity purification provides the most inclusive analysis of nucleoid associated proteins. by Nina Rajala (693865)

“…The pie-chart shown here illustrates the distribution of the 366 enriched proteins identified with the X-ChIP method in regular HEK293 TwinkleFLAG and measured in HEK293 TwinkleFLAG ρ° in the following classes: not detected (absent), 95 proteins; ≥2 fold decrease, 163 proteins; no change, 100 proteins or ≥2 fold increase, 8 proteins(see also <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116726#pone.0116726.s004" target="_blank">S3 Table</a>). …”

<i>DDI1/2</i>-deficient effects on the rapamycin-responsive signaling to Nrf1 and proteasome. by Keli Liu (5937368)

“…<p>(A) <i>WT</i> and <i>DDI1</i>^{<i>–∕–</i>}(<i>DDI2</i>^<i>insC</i>) cell lines were transfected with an expression construct for Nrf1-V5 (+) or empty pcDNA3 vector (–) and then examined by Western blotting with V5 antibody (<i>a1</i>, <i>a3</i>); ß-actin acts as a loading control. …”

Therapeutic Non-Toxic Doses of TNF Induce Significant Regression in TNFR2-p75 Knockdown Lewis Lung Carcinoma Tumor Implants by Sharath P. Sasi (541865)

“…Compared to 3 control groups, p75KD/LLC+TNF showed >2-5-fold decreases in tV (p<0.001) and tW (p<0.0001). …”

Text S1 - Down-Regulating Sphingolipid Synthesis Increases Yeast Lifespan by Xinhe Huang (185390)

“…Figure S2: Myriocin treatment decreases cell size. DBY746 cells were grown with and without myriocin (Myr) as in a CLS assay using SDC medium (pH 4.5, 3X iron). …”

CTR-C PDZ- binding motif mutation and TJ disruption and invasion. by Ahmed Aljameeli (2548528)

“…<p>A. Transepithelial Electric Resistance (TER): Polarized PC-3v, PC-3-CTRwt and PC-3CTR-∆ESS cells were serum-starved for 4 hours, then treated with/without 50 nM CT. …”

PMN-MDSC induce EMT in vitro and in vivo. by Benjamin Toh (204080)

“…Red, S100A4; blue, Heamatoxylin (Nuclear stain). Panel I shows a decrease in the percentage of S100A4⁺ cells in the tumors depleted from PMN-MDSC (depletion scheme A). …”

Targeted expression of TeTxLC, Shi, Kirand Glued-DN affects the architecture of the CSDn by Bidisha Roy (37349)

“…The neuron expressing inactive tetanus toxin (UAS-/+; RN2--FRT-CD2-FRT-Gal4, UAS-/+) have dendrites (arrow in (b)) and terminal arbors (h) comparable to WT. Ectopic expression of active form of tetanus toxin (UAS-/+; RN2--FRT-CD2-FRT-Gal4, UAS-/+) results in dramatic increase in ipsilateral dendrites (arrows in (c)) and a marked decrease in contralateral terminals (i). …”

Contribution of anti-gp120 antibodies to the overall neutralizing activity of HIV+ plasmas. by Iliyana Mikell (120166)

“…<p>(A) Log10 decrease in neutralizing activity caused by the elimination of anti-gp120 antibodies, and (B) Log10 decrease in neutralizing activity of plasmas in the presence of D368R. …”