Diadinoxanthin (Ddx) concentration and de-epoxidation state (DES). by Benjamin Schellenberger Costa (461158)

“…O: no significant difference between WT and aureochrome 1a silenced strain; −: significant decrease in aureochrome 1a silenced strain compared to WT; +: significant increase in aureochrome 1a silenced strain compared to WT.…”

Behavioral stress delays androgen ablation-induced prostate involution and apoptosis via β2-AR and BAD phosphorylation. by Sazzad Hassan (454373)

“…Intact calm mice (0c), numbers under the columns indicate days of bicalutamide treatment; BAD^wt/wt mice with wild type BAD; BAD^wt/wt +ICI, mice treated with ICI118,551; BAD^3SA/WT, mice with knockin on phosphorylation-deficient BAD3SA mutant (n = 3 to 5 in each group). …”

Overexpression of Sano results in smaller apical domains. by SeYeon Chung (256943)

“…WT (F). <i>btl-Gal4</i>-driven Sano-overexpressing trachea (G) reveal a significant decrease in apical domain size. …”

Changes in transepithelial electrical resistance (cTER) upon cAMP. by Natalia Molenda (580354)

“…Stimulation with 8cpt-cAMP caused a decrease of TER in CFBE-WT cells (blue triangles) and an increase for CFBE-delF (brown circles). …”

Combined expression of pTFs promotes transdifferentiation efficiency, however only their sequential expression increases β-cell maturation. by Dana Berneman-Zeitouni (519463)

“…<p>Cultured adult human liver cells were infected with <i>Ad-CMV-Pdx1</i> (1000 MOI), <i>Ad-CMV-Pax-4</i> (100 MOI) and <i>Ad-CMV-Mafa</i> (10 MOI) together or in a sequential manner as summarized in (A) (treatments B–E) or with control virus (<i>Ad-CMV-β-gal</i>, 1000 MOI, treatment A), and analyzed for their pancreatic differentiation six days later. …”

Supplemental Figure 1 by lsimo2@lsuhsc.edu lsimo2@lsuhsc.edu (6704447)

“…There was a main effect of OVX to decrease HOMA-β at study endpoint. …”

The effects of FRLFE on the NF-κB-dependent transcription of the <i>iNOS</i> gene. by Ryota Yamanishi (547533)

“…<p>(<b>A</b>) FRLFE decreases the iNOS promoter activity. …”

Table1_Fibrates for the Treatment of Primary Biliary Cholangitis Unresponsive to Ursodeoxycholic Acid: An Exploratory Study.docx by Guilherme Grossi Lopes Cançado (10373078)

“…</p><p>Results: In total, 27 patients (100% women, mean age 48.9 ± 9.2 years) with PBC were included. …”

Transcriptome Analyses of a Salt-Tolerant Cytokinin-Deficient Mutant Reveal Differential Regulation of Salt Stress Response by Cytokinin Deficiency by Rie Nishiyama (49902)

“…WT-0 mM, <em>ipt1,3,5,7</em>-200 mM vs. <em>ipt1,3,5,7</em>-0 mM and <em>ipt1,3,5,7</em>-200 mM vs. …”

Polarity independent brain structures form from stem cells that have progressed through S-phase during the first 16 hours of regeneration. by Deborah J. Evans (195583)

“…<p>(A) Proliferation assay of single and double amputated trunk pieces at different times of regeneration indicate double cuts produce a decrease in the amplitude of both characteristic mitotic peaks and a delay in the first mitotic peak (mean number of mitotic cells, error bars are +/− 1 SEM of the mean, n = 12 at each time point). …”

(A) Schematic presentation of the human AID protein sequence along with the positions of the lysine residues mutated in the various constructs by Said Aoufouchi (49316)

“…(B) BL2 clones expressing either WT-AID-EGFP (sample 1, WT), or a lysineless mutant of AID (Kzero-AID-EGFP; sample 2, Kzero) were incubated with the indicated inhibitors for 5 h. …”

Although Hrq1 is needed for cisplatin resistance, it is degraded by the proteasome upon cisplatin exposure. by Thong T. Luong (13833935)

“…The experiment was performed five times with mean and standard error plotted (Raw densitometry data in Sheets A-E in <b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010122#pgen.1010122.s007" target="_blank">S1 Data</a></b>). …”

Biochemical characterization of the endolysins of the lactococcal phages P008, c2, 1358, and P335. by Frank Oechslin (4825476)

“…The color gradient indicates the percent of decrease in absorbance measured over time. Values are means and standard deviations from triplicates (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001740#pbio.3001740.s016" target="_blank">S1 Data</a>). …”

The conserved motifs in the SBD of PluR and PauR are essential but not sufficient for ligand-binding specificity. by Sophie Brameyer (731567)

“…(<b>B</b>) and (<b>D</b>): The RLU values are depicted 2 h after the addition of the distinct signaling molecules, either 3.5 nM PPYD, 3.5 nM DAR or 100 nM C8-HSL. Reference line was set to 370 RLUs to compare better with <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0124093#pone.0124093.g002" target="_blank">Fig 2</a>.…”

MIA/CD-RAP activates the <i>p54^nrb</i> promoter via the transcription factor YBX1. by Rainer Schmid (496848)

“…<p>(<b>A</b>) YBX1 activity as measured using a reporter gene assay revealed a significant decrease in YBX1 promoter activity in MIA-/- mMSCs compared with WT mMSCs (III) (**p<0.01). …”

Viral ORF57 inhibits eIF2α phosphorylation. by Nishi R. Sharma (4543936)

“…The error bar indicates mean ± SD (n = 3). (D-E) KSHV lytic infection in BCBL-1 cells does not increase eIF2α phosphorylation, but rather decrease arsenite-induced eIF2α phosphorylation. …”

Abberant α-Synuclein Confers Toxicity to Neurons in Part through Inhibition of Chaperone-Mediated Autophagy by Maria Xilouri (264240)

“…</p><h3>Methods and Findings</h3><p>Novel inducible SH-SY5Y and PC12 cell lines expressing human WT and A53T ASYN, as well as two mutant forms that lack the CMA-targeting motif were generated. …”

Proliferation of CTS-treated cells. by Rebecca J. Clifford (497197)

“…<p>A) Normal MCF10A cells exhibited a concentration-dependent decrease in BrdU incorporation (proliferation) when treated with 500 nM ouabain, 50 nM bufalin or 100 nM bufalin for 2 hours (p<0.01). …”

CV1720 cells show impaired ATR–dependent DNA damage responses. by Tomoo Ogi (122258)

“…<p>A) WT, DK0064 (ATR–SS), CV1720 (patient), CV1780 (patient's mother) and CV1783 (patient's father) cells were exposed to 5 Jm⁻² UV and the mitotic index (MI) assessed 2 h post exposure. …”

The CCDC66 depletion disrupts normal tissue organization and signaling in 3D and 2D cultures. by Jovana Deretic (13113617)

“…Mean cilia percentage is 59.78 for shControl and 53.80 for shCcdc66, with a fold change decrease of 0.90. …”