MIA/CD-RAP activates the <i>p54^nrb</i> promoter via the transcription factor YBX1. by Rainer Schmid (496848)

“…<p>(<b>A</b>) YBX1 activity as measured using a reporter gene assay revealed a significant decrease in YBX1 promoter activity in MIA-/- mMSCs compared with WT mMSCs (III) (**p<0.01). …”

Abberant α-Synuclein Confers Toxicity to Neurons in Part through Inhibition of Chaperone-Mediated Autophagy by Maria Xilouri (264240)

“…</p><h3>Methods and Findings</h3><p>Novel inducible SH-SY5Y and PC12 cell lines expressing human WT and A53T ASYN, as well as two mutant forms that lack the CMA-targeting motif were generated. …”

Proliferation of CTS-treated cells. by Rebecca J. Clifford (497197)

“…<p>A) Normal MCF10A cells exhibited a concentration-dependent decrease in BrdU incorporation (proliferation) when treated with 500 nM ouabain, 50 nM bufalin or 100 nM bufalin for 2 hours (p<0.01). …”

CV1720 cells show impaired ATR–dependent DNA damage responses. by Tomoo Ogi (122258)

“…<p>A) WT, DK0064 (ATR–SS), CV1720 (patient), CV1780 (patient's mother) and CV1783 (patient's father) cells were exposed to 5 Jm⁻² UV and the mitotic index (MI) assessed 2 h post exposure. …”

Land cover, more than monthly fire weather, drives fire-size distribution in Southern Québec forests: Implications for fire risk management by Jean Marchal (3319485)

“…Fires were highly selective on fuel-type under a wide range of fire weather conditions: specifically, deciduous forest, lakes and to a lesser extent recently burned areas decreased the expected fire size in their vicinity compared to conifer forest. …”

Data_Sheet_1_Health Effects of Metabolic Risks in the United States From 1990 to 2019.docx by Ruifang Chen (2451214)

“…</p>Results<p>In 2019, the age-standardized death and DALY rates attributable to metabolic risks were 174.9 and 4738.7 per 100,000 people, accounting for 33.1% and 18.2% of death and DALY rates from all causes in the US, and there was a decrease by −32.5% and −21.2% in age-standardized death and DALY rates since 1990. …”

Is Obstructive Sleep Apnea Associated with Cardiovascular and All-Cause Mortality? by Xiahui Ge (437665)

“…<div><p>Background</p><p>Studies have reported inconsistent findings regarding the association between obstructive sleep apnea (OSA) and future risks of cardiovascular and all-cause mortality. We conducted a meta-analysis to investigate whether OSA is an independent predictor for future cardiovascular and all-cause mortality using prospective observational studies.…”

Epigenetic Regulatory Effect of Exercise on Glutathione Peroxidase 1 Expression in the Skeletal Muscle of Severely Dyslipidemic Mice by Albert Nguyen (2580886)

“…Of these genes, only <i>Gpx1</i> exhibited changes in DNA methylation associated with dyslipidemia and exercise: we observed both increased DNA methylation with dyslipidemia and a transient decrease in DNA methylation with exercise. …”

CaMKII selective peptide inhibitors reduces myocardial fibrosis in SHRs. by Ersilia Cipolletta (760356)

“…SHR treated with AntCaNtide and tat-CN17β showed a decrease of interstitial fibrosis and reduced cardiomyocytes size when compared to SHR untreated group. …”

Synthetic Multivalent Antifungal Peptides Effective against Fungi by Rajamani Lakshminarayanan (321411)

“…Replacing the first arginine led to a 2–4 fold decrease in antifungal activities and reduced membrane disruption properties. …”

LPS triggered chemotactic signaling through fAR1. by Miao Pan (5285834)

“…A Student <i>t</i> test indicated a statistically significant difference in LPS binding between <i>far1</i>^<i>−</i> and <i>WT</i> cells (* indicates <i>P</i> < 0.01). …”

30 Hz stimulation does not permit recovery from previous ensemble recall. by Casey M. Baker (16033144)

“…<p>(A) We categorized the 8 stimulations for each stimulation period as either odd or even stimulations. …”

Data_Sheet_1_The Sensitivity of Subsurface Microbes to Ocean Warming Accentuates Future Declines in Particulate Carbon Export.pdf by Emma Louise Cavan (6178583)

“…In line with observations from polar regions and the deep ocean we imposed an elevated temperature sensitivity (E_a = 1.0 eV) to cooler regions; firstly to the Southern Ocean (south of 40°S) and secondly where temperature at 100 m depth <13°C. …”

Optimizing light-cured composite through variations in camphorquinone and butylhydroxytoluene concentrations by Hani NASSAR (12805999)

“…Sixteen groups of resin composite were prepared using combinations of four CQ (0.1%, 0.5%, 1.0%, and 1.5%) and four BHT (0.0%, 0.5%, 1.0%, and 1.5%) concentrations. …”

Loss of Slfn3 induces a gender-dependent repair vulnerability after 50% bowel resection by Emilie DeKrey (9389738)

“…Mitotic marker, Phh3+, and proliferation marker expression of Lgr5, FoxL1, and PDGFRα were increased after resection in male WT but this effect was blunted in male Slfn3KO mice. …”

Effect of inhibitors of p38 MAPK or PKC on stimulated shedding by ADAM17T735A and ADAM17ΔC. by Katherine C. Hall (180988)

“…C) <i>Adam17−/−</i> mEFs transfected with TGFα together with WT ADAM17 were stimulated with 5 ng/ml IL-1β, 1 µM anisomycin or 25 ng/ml PMA in the presence or absence of 4 µM BIM I. …”

Myelin alteration in 8-week-old TRAF4-KO mice. by Sébastien Blaise (332585)

“…(C): Western blot analysis of the myelin-specific MBP marker and of the interglial-specific TJ marker claudin 11 (cl 11) showed a decreased expression level of both proteins in 4 independent TRAF4-KO cerebellum protein extracts (lanes 5–8) compared with 4 WT samples (lanes 1–4) ; tubulin served as a loading control. …”

Role of voice therapy in adherence to voice rest (King et al., 2021) by Renee E. King (11409101)

“…</div><div><b>Results:</b> Talking decreased postprocedure by 63% in the therapy group and 65% in the counseling group, both significantly more than the 35% decrease measured in the evaluation group. …”

Supplemental data of the manuscript “Accumulation of seminolipid in Sertoli cells is associated with increased levels of reactive oxygen species and male subfertility: Studies in a... by Kessiri Kongmanas (7467368)

“…</p> <p><b>Supplemental Figure S7</b> Levels superoxide anions (2HE) and other ROS + oxidants (Eth) of the cauda epididymis of 5-month-old <i>Arsa^-/-</i> mice and WT mice<b> (A)</b> and of the caput epididymis of 5-month-old and 8-month-old <i>Arsa^-/-</i> mice and age-matched WT mice <b>(B)</b>. …”

Expression of two <i>tenascin</i> genes is affected by temperature. by Che-Yi Lin (218292)

“…<p><i>In situ</i> hybridization against <i>tenascin-c</i> (<i>tnc</i>) (A-H) and <i>tenascin-w</i> (<i>tnw</i>) (L-O) in 22-ss wild-type (WT) and <i>s1pr2^as10</i> (<i>as10</i>) mutant embryos raised at 28.5°C or 22.5°C. …”