Datasheet1_The 18-year risk of cancer, angioedema, insomnia, depression, and erectile dysfunction in association with antihypertensive drugs: post-trial analyses from ALLHAT–Medica... by Xianglin L. Du (11726072)

“…The adjusted 18-year risk of angioedema was elevated in those receiving lisinopril than in those receiving amlodipine (hazard ratio: 1.63, 95% CI: 1.14–2.33) or in those receiving chlorthalidone (1.33, 1.00–1.79), whereas the adjusted 18-year risk of insomnia was statistically significantly decreased in those receiving lisinopril than in those receiving amlodipine (0.90, 0.81–1.00).…”

Table1_Exposure to artificial light at night mediates the locomotion activity and oviposition capacity of Dastarcus helophoroides (Fairmaire).DOCX by Xiang-lan Jiang (14589878)

“…Finally, the potential influence of exposure to four ecologically relevant intensities of artificial light at night (0, 1, 10 or 100 lx) on oviposition capacity was studied. The results showed that lifetime exposure to bright artificial light (1–100 lx) at night decreased the number of eggs laid relative to those laid with no lighting at night. …”

Data_Sheet_1_Diatom Biodiversity and Speciation Revealed by Comparative Analysis of Mitochondrial Genomes.ZIP by Yichao Wang (399833)

“…<p>Diatoms (Bacillariophyta) constitute one of the most diverse and ecologically significant groups of phytoplankton, comprising 100,000–200,000 species in three classes Bacillariophyceae, Mediophyceae, and Coscinodiscophyceae. …”

Table_1_Diatom Biodiversity and Speciation Revealed by Comparative Analysis of Mitochondrial Genomes.DOCX by Yichao Wang (399833)

“…<p>Diatoms (Bacillariophyta) constitute one of the most diverse and ecologically significant groups of phytoplankton, comprising 100,000–200,000 species in three classes Bacillariophyceae, Mediophyceae, and Coscinodiscophyceae. …”

Inhibition of <i>Nlu-miR-34</i> in SW strain by antagomir-34. by Xinhai Ye (6857771)

“…<p>(A) The expression of <i>Nlu-miR-34</i> was significantly decreased by injecting antagomir-34 (<i>p</i> = 0.004). …”

Exogenous expression of variants of the small G protein, N-Ras, inhibits HIV-1 gene expression. by Raymond W. Wong (8463498)

“…<p>(<b>A-D</b>) HeLa rtTA-HIV(Gag-GFP) cells were (A) treated with/without 5342191 per <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1008307#ppat.1008307.g001" target="_blank">Fig 1</a> or (B-D) transfected with WT, oncogenic (12D), or dominant-negative (17N) N-Ras, or mock plasmid and co-transfected with (+) tTA (or without, -) to activate HIV-1 expression. …”

Protein disulfide isomerases (PDIs) negatively regulate ebolavirus structural glycoprotein expression in the endoplasmic reticulum (ER) via the autophagy-lysosomal pathway by Bin Wang (30851)

“…</p> <p><b>Abbreviations:</b> 3-MA: 3-methyladenine; 4-PBA: 4-phenylbutyrate; ACTB: β-actin; ATF: activating transcription factor; ATG: autophagy-related; BafA1: bafilomycin A₁; BDBV: <i>Bundibugyo</i> ebolavirus; CALR: calreticulin; CANX: calnexin; CHX: cycloheximide; CMA: chaperone-mediated autophagy; ConA: concanamycin A; CRISPR: clusters of regularly interspaced short palindromic repeats; Cas9: CRISPR-associated protein 9; dsRNA: double-stranded RNA; EBOV: <i>Zaire</i> ebolavirus; EDEM: ER degradation enhancing alpha-mannosidase like protein; EIF2AK3/PERK: eukaryotic translation initiation factor 2 alpha kinase 3; Env: envelope glycoprotein; ER: endoplasmic reticulum; ERAD: ER-associated protein degradation; ERN1/IRE1: endoplasmic reticulum to nucleus signaling 1; GP: glycoprotein; HA: hemagglutinin; HDAC6: histone deacetylase 6; HMM: high-molecular-mass; HIV-1: human immunodeficiency virus type 1; HSPA5/BiP: heat shock protein family A (Hsp70) member 5; IAV: influenza A virus; IP: immunoprecipitation; KIF: kifenesine; Lac: lactacystin; LAMP: lysosomal associated membrane protein; MAN1B1/ERManI: mannosidase alpha class 1B member 1; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; MARV: Marburg virus; MLD: mucin-like domain; NHK/SERPINA1: alpha1-antitrypsin variant null (Hong Kong); NTZ: nitazoxanide; PDI: protein disulfide isomerase; RAVV: Ravn virus; RESTV: Reston ebolavirus; SARS-CoV: severe acute respiratory syndrome coronavirus; SBOV: <i>Sudan</i> ebolavirus; sGP: soluble GP; SQSTM1/p62: sequestosome 1; ssGP: small soluble GP; TAFV: Taï Forest ebolavirus; TIZ: tizoxanide; TGN: thapsigargin; TLD: TXN (thioredoxin)-like domain; Ub: ubiquitin; UPR: unfolded protein response; VLP: virus-like particle; VSV: vesicular stomatitis virus; WB: Western blotting; WT: wild-type; XBP1: X-box binding protein 1.…”

lncCyt b cooperates with hnRNPA2B1 to modulate glycolysis and exhibits physiological significance. by Jia Li (160557)

“…(E) CCK-8 assays showing the decreased proliferation of A549 cells by lncCyt b or hnRNPA2B1 knockdown. …”

NPCs derived from CUL9 KO NSCs express key markers of neuronal differentiation. by Natalya A. Ortolano (10291721)

“…NPCs were produced twenty-five days after neuronal differentiation initiated. …”

Relative activity of parental and engineered mesothelin HiTs against target cell lines by IFN-γ enzyme-linked immune absorbent spot. by Martyn J. Hiscox (18310076)

Data_Sheet_1_Ecologically different earthworm species are the driving force of microbial hotspots influencing Pb uptake by the leafy vegetable Brassica campestris.pdf by Cevin Tibihenda (17090521)

“…A significant shift in the bacterial community was observed in the treatments with E. fetida inoculation at 500 and 1,000 mg·kg⁻¹ Pb, where the G⁺/G⁻ bacteria ratio was significantly decreased compared to no earthworm inoculation. …”

Regulation of <i>ryhB1</i> and <i>ryhB2</i> by σ^S in <i>Salmonella</i>. by Selma Metaane (12329248)

“…Relative quantification of bands intensity (normalized to the 5S RNA) indicated that the Δ<i>rpoS</i> mutation decreased by about ten-fold the amounts of RyhB1 and RyhB2 detected in the wild-type strain, as previously reported [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0265511#pone.0265511.ref005" target="_blank">5</a>]. …”

Evaluation of heavy metal accumulation and tolerance in oxalic acid-treated <i>Phragmites australis</i> wetlands for textile effluent remediation by Suliman Mohammed Suliman Alghanem (18854887)

“…Multiple treatments, comprising the application of OA at a concentration of 10 mM and WW at different dilutions (25%, 50%, 75%, and 100%), were employed, with three replications of each treatment. …”

SPI under <i>K</i> different distance ranges. by Thao Vu (3363083)

“…<p><i>K</i> values were incremented from 25 to 100 in steps of 5. At each <i>K</i>, a sequence of distance breaks was generated by linearly decreasing from <i>d</i>_<i>K</i> to 0 on a log scale. …”

Effect of MT on apoptosis in experimental groups. by Eduardo Peña-Mercado (13257039)

“…(a). Scale bar: 100 μm (a), (c) and (e). Magnification: Scale bar: 50 μm (b), (d) and (f). …”

Characterization of <i>Acinetobacter</i> type IVa pilus components. by Ruben Iruegas (6203684)

“…Taxa are ordered according to increasing phylogenetic distance to <i>A</i>. <i>baumannii</i> using the information provided in [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010646#pgen.1010646.ref021" target="_blank">21</a>] and [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010646#pgen.1010646.ref100" target="_blank">100</a>]. …”

Morphological changes in the hindbrains of <i>Bmpr</i> knockout mutants. by Lihua Qin (494786)

“…(A, B) H&E staining shows that the pontine gray nucleus was dramatically decreased in the <i>Bmpr</i> double knockout mutant (B, arrow) compared to normal (A, arrow). …”

Mapping rRNA 2’-O-methylations and identification of C/D snoRNAs in Arabidopsis thaliana plants by J. Azevedo-Favory (10160017)

Sirtuin 3 deficiency accelerates Angiotensin II-induced skeletal muscle atrophy by Jianheng Zheng (5531810)

“…SIRT3 deficiency accelerated Ang II-induced loss of lean mass and protein hyper-acetylation, while the activities of mitochondrial oxidative enzymes, such as complex I and complex V, were significantly decreased. Furthermore, SIRT3 deficiency accelerated the Ang II-induced shift from slow-twitch towards fast-twitch fibres. …”

Fig 2 - by Rabiya Arif Ansari (14290013)

“…(a) The number of research publications between 1970 and 2019 has grown exponentially, but the proportion of textbook coverage has decreased from one textbook sentence per 200 scientific publications to one textbook sentence per 1,100 scientific publications. …”