Pre-treatment of IOZCAS-Spex-II cells with CPT and HCPT decreased Topo1 specific activity in a time-dependent manner. by Lan Zhang (90951)

Pre-treatment of IOZCAS-Spex-II cells with CPT and HCPT decreased Topo1 specific activity in a dose-dependent manner. by Lan Zhang (90951)

Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5‑ASA–PABA–MAC and 5‑ASA–PABA–Diamine for the T... by Jiaxing Zhao (3965057)

“…Specifically, compound <b>20g</b> displayed a 3.67-fold decrease of plasma AUC_{(tofacitinib, 0–∞)} and a 9.61-fold increase of colonic AUC_{(tofacitinib, 0–12h)}, compared with tofacitinib at a molar equivalent oral dose. …”

HRMECs treated with 3-Deazaneplanocin A (DZNep) chemical inhibitor demonstrated increased miR-200b and decreased VEGF expression. by Michael Anthony Ruiz (726055)

“…[NG = 5mM D-glucose, HG = 25mM D-glucose, NG+DMSO = 5mM D-glucose + 0.05% DMSO, HG+DMSO = 25mM D-glucose + 0.05% DMSO, NG+DZNEP = 5mM D-glucose + 5μM DZNep, HG+DZNEP = 25mM + 5μM DZNep; identical letters represent groups that are not significantly different; p < 0.05; n = 6; data expressed as mean ± SEM, normalized to β-actin for VEGF and U6 for miR-200b, expressed as a fold change of NG].…”

Aggrecan knockdown ATDC5 chondroprogenitor cells have decreased Alcian blue staining and absorbance levels compared to control cells after ITS stimulation. by Juanita K. Hodax (6848540)

Rab7A decreases BST2 cell surface expression and is required for Vpu-induced BST2 cell surface downregulation. by Marina Caillet (198168)

“…HeLa cells transfected with either control siRNA (siLuc) or siRNA targeting Rab7A were infected with VSV-G pseudotyped NL4-3 HIV-1 (WT or Udel) at a MOI of 0.5. …”

<i>dnak14</i> mutant harbors a transposon insertion in the <i>dnaK</i> coding region and specifies a truncated DnaK protein. by Carissa Chan (18310140)

Basal and radiation-induced ROS in DC lymphocytes. by Larisa Pereboeva (322533)

Folding and stability of GDAP1 as affected by CMT mutations. by Aleksi Sutinen (10039145)

Subjects:

Heat inactivation curves for the WT SULT1A1 protein and the 5C2, 5F8 and D249G SULT1A1 mutants. by Ilana Berger (198531)

“…The decrease in stability of the 5F8 mutant, relative to 1E8, and the D249G mutant, relative to the WT protein, highlight the trade-off between thermostability and the acquisition of new catalytic properties (see text for details).…”

S C-terminal mutations that decrease ezrin interaction enhance transduction by pseudotyped particles in Vero E6 cells. by Jean Kaoru Millet (117227)

Ethanol withdrawal (EW) decreases GluN2A subunit levels. by Marina Rubio (345805)

“…<p>NMDA subunit protein levels measured by Western blot analysis: GluN2A levels (B) decrease during ethanol withdrawal, whereas the levels of GluN1 (A) and GluN2B (C) remain unaltered. …”

HPV16 PsV infection decreases following SLPI treatment or anti-annexin A2 antibody inhibition of A2t. by Andrew W. Woodham (140650)

AgLDL induce the decrease of ΔΨm and ATP in THP-1 macrophages, without mtROS or apoptosis. by Gabriela M. Sanda (10031559)

Over-expression of ANX RLKs inhibits pollen germination, pollen tube growth, and decreases male transmission efficiency. by Aurélien Boisson-Dernier (490023)

Gene expression of <i>Hdac7</i> WT, HET and KO osteoclast cultures. by Melissa Stemig (723969)

Damsin (D) and ambrosin (A) treatment decreases the CSC population. by Wendy Soria Sotillo (4408105)

<i>S.</i> Typhimurium-infected mice have tissue inflammation and thrombosis, increased hematopoiesis, and decreased splenic iron. by Diane E. Brown (160264)

“…Mean number of TER119^med pro-erythroblasts per spleen increased 6.8-fold in infected mice, while the mean number of TER119^high cells, corresponding to all nucleated erythroblasts subsequent to the pro-erythroblast stage <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0009441#pone.0009441-Socolovsky1" target="_blank">[40]</a>, increased 3.6-fold. …”

Image_1_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Image_1_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”