Simultaneous ablation of Syt1 and Syt7 decreases the RRP size at inhibitory synapses: Rescue by WT but not mutant Syt1 or Syt7. by Taulant Bacaj (803415)

“…Recordings were performed in the presence of 1 μM tetrodotoxin, 20 μM CNQX, and 50 μM AP5 to isolate inhibitory currents. <b>B.</b> Simultaneous ablation of Syt1 and Syt7 decreases the RRP size of inhibitory synapses in a manner that is rescued by WT Syt7 (Syt1^WT) but not Syt7 with mutations in the top C2 domain sequences containing the Syt7 Ca²⁺ binding sites (Syt7^C2A*^B*). …”

<i>Bahd1</i>-knockout mice display decreased weight and fat mass and lower cholesterol, glucose and leptin levels. by Goran Lakisic (2551717)

Reduced I_A decreases the stimulus threshold for short-term synaptic plasticity. by Ángela Fontán-Lozano (193161)

NEMO knockout murine dermal fibroblasts show a decreased nuclear translocation of p65. by Patrick Meyer (3395285)

<i>Mertk</i>^<i>-/-</i> macrophages exhibit unpolarized distribution of filamentous actin and myosin II, and decreased FAK phosphorylation. by Yong Tang (161879)

“…Scale bars in (A) and (B), 5 μm. (C) Western blotting shows decreased FAK phosphorylation at tyrosine 397 after addition of apoptotic T cells for the indicated time points. …”

Decreased reductase activity and increased round body formation in the <i>gpsA</i> mutant. by Dan Drecktrah (36180)

Oral UOX decreased SUA (A), BUN (B) and Cr (C) (mean ± SD, n = 10). by Yu Yun (4710340)

Overexpression of SV2A-EGFP in wild-type neurons results in reduced EPSC amplitude and decreased synaptic depression. by Amy Nowack (336337)

Decreases in locomotor responses to a single METH injection in <i>Ptprz</i>-KO mice. by Akihiro Fujikawa (122649)

DOX decreases body mass gain over time in a sub-chronic toxicity model. by Gonçalo C. Pereira (156673)

Wnt5a expressing tumors demonstrate a decrease in markers of the basal tumor subtype. by Stephanie L. Easter (662168)

“…MMTV-Wnt1;MMTV-Wnt5a tumors demonstrated a significant decrease in K6-expressing cells as measured by T-test (* = p<0.05).…”

Mitochondrial dysfunction is driven by decreased mitochondrial dynamics. by Piero Dalle Pezze (622889)

“…<p>(A) Sensitivity analysis averaged along the time course for the mitochondrial species in the model by varying the mitochondrial-related kinetic rate constant parameters. …”

HAstV-8 (D471S, N512D) spike has decreased or no binding to FcRn compared to wild-type HAstV-8 spike. by Catalina Aguilera-Flores (21743843)

Decreased consumption of methionine sulfoxide (MetO) by the <i>V</i>. <i>cholerae</i> Δ<i>gcvT</i> mutant attenuates virulence by promoting intestinal lipid mobilization and insuli... by Audrey S. Vanhove (4090594)

Tunicamycin produces a concentration- and time-dependent decrease in cell viability in SH-SY5Y cells concomitant with caspase-3 activation. by Arindam P. Ghosh (317870)

“…<p>(A) Treatment of SH-SY5Y cells with tunicamycin (0.1–5µM) for 24 h caused a progressive decrease in cell viability as measured by Calcein AM cleavage assay. …”

Mean ± SD values of unipedal stance parameters evaluated at the different time points of the postural training session. by Cristina Dolciotti (16317330)

Cardiac overexpression of miR-130a results in decreased FOG-2 expression and a thin ventricular myocardial wall. by Gene H. Kim (371958)

OCA alone markedly decreases and combined with Gemcitabine or Cisplatin abrogates growth of iCCA xenografts. by S. Di Matteo (6260417)

“…After 4 weeks, when the tumor size was approximately 100 mm³ (T₀) mice were treated with OCA (0.03% w/w, 30 mg/kg) alone or combined with Cisplatin (2.4 mg/Kg in 100 μl) or Gemcitabine (1.05 mg/Kg in 100 μl) for 5 additional weeks. a) Results are expressed as percent increase in tumor volume at different time points. …”

Clinical and genetic characteristics of 5 patients harboring mutations in the <i>NR5A1</i> gene. by Jana Malikova (615672)

Subjects:

SinV infection causes a decrease in Neuro 2a cells number and viability. by Leandro Silva da Costa (327641)