Functional characterization of differentiated astrocytes. by In Ki Cho (6494564)

“…<p>(A) Representative traces of ionic currents evoked by ramp protocol (left) and voltage-step protocol (right) in cultured WT, HD, and shHD astrocytes. The holding potentials for all the cells were -60mV. …”

Single, triple, and quadruple knockdowns of <i>sox2/3/19a/19b</i>. by Yuichi Okuda (249308)

“…A mixture of indicated combinations of MOs (i.e., a mixture of six MOs, 5.4 ng in total) was used to simultaneously knockdown three out of the four B1 <i>sox</i> genes. …”

Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension by Thiruveni Ramkumar (17075051)

“…However, a sub-group comparison of neonates (with initial blood glucose <2.6 mmol/L) showed methyldopa to be marginally associated with a 2 mmol/L decrease from the mean initial blood glucose, mean 1.6 ± 0.5 mmol/L, and methyldopa (1.4 ± 0.5 mmol/L; p= .045). …”

Ethanol dependent phenotype of dopaminergic pathway mutants. by Pratima Pandey (8734935)

“…Please note that although we did not find a significant difference between WT and <i>dop-1</i> animals in this experiment, we did however find a significant decrease in the number of body bends seen in <i>dop-1</i> mutants that were outcrossed more times. …”

Effect of TNF-α on apoptosis in human eosinophils. by Hannu Kankaanranta (23356)

“…In (B and C) figures in top right corner represent percentage of cells showing decreased DNA content. In (D) is shown the DNA fragmentation in eosinophils cultured without (lane 1) and with 10 ng/ml TNF-α (lane 2). …”

IRS-1 levels negatively correlate with ERK activation. by Hui He (356808)

“…<p>Following 24 hours serum starvation, RECs were cultured for three days in either normal glucose (5 mM, NG) or high glucose (25 mM, HG). Cells were then treated with normal saline (vehicle control) or KZ-41 (10 μM). …”

Effect of LLDPE on Aging Resistance and Thermal, Mechanical, Morphological Properties of UHMWPE/LLDPE Blends by Caroline Martins dos Santos (5667635)

Data_Sheet_1_Metabolite Profile, Ruminal Methane Reduction, and Microbiome Modulating Potential of Seeds of Pharbitis nil.docx by Rajaraman Bharanidharan (5635310)

“…PA is enriched in polyunsaturated fatty acids dominated by linoleic acid (C18:2) and flavonoids such as chlorogenate, quercetin, quercetin-3-O-glucoside, and quinic acid derivatives. PA decreased (p < 0.001) methane (CH₄) production linearly in vitro with a reduction of 24% at doses as low as 4.5% DM substrate. …”

Effect of the sampling process upon a LH level signal with regular increasing sampling frequency. by Alexandre Vidal (153129)

“…Case F (right panels): the pulse amplitude decreases regularly and the basal line decreases regularly. …”

STATc is a key regulator of the transcriptional response to hyperosmotic shock-0 by Jianbo Na (12352)

“…Size bar is 10 μm. (B) Decrease of cell volume in response to hyperosmotic condition. cells were treated with increasing sorbitol concentrations for 5 minutes. …”

Additional file 7 of Fecal profiling reveals a common microbial signature for pancreatic cancer in Finnish and Iranian cohorts by Heidelinde Sammallahti (21103706)

Genome-based model for differentiating between infection and carriage Staphylococcus aureus by JianYu Chen (19141864)

RenTg mice are hypertensive and develop chronic kidney disease progressively with the age. by Anne-Cecile Huby (291994)

“…<p>Systolic blood pressure was highly increased in RenTg mice since the age of 3 months as compared to aged matched WT controls (A). Urinary excretion of albumin progressively increased with age to reach at 12 months highly elevated values in RenTg mice (B) whereas GFR significantly decreased (C). …”

HMHA1 regulates RhoGTPase activity <i>in vivo</i>. by Bart-Jan de Kreuk (462330)

“…Data are mean values of five independent experiments. Error bars indicate SEM. ns, not significant. * p<0.05, ** p<0.01. …”

H4R-mediated inhibition of clonogenic cell proliferation and/or differentiation. by Anne-France Petit-Bertron (261234)

“…(B) Decreased number of cell divisions upon H4R stimulation. …”

<i>Hdac4</i> reduction does not alter the expression levels of <i>HTT</i> exon 1, endogenous <i>Htt</i>, or other <i>Hdacs</i>. by Michal Mielcarek (195209)

“…All Taqman qPCR values were normalized to the geometric mean of three housekeeping genes: <i>Atp5b</i>, <i>Canx</i>, and <i>Rpl13a</i>. …”

Dorsal lateral striatum MSN CaMKII inhibition reduces excitatory transmission independently of changes in release probability. by Jason R. Klug (132807)

“…PPR (50 ms ISI) for EAC3I-containing and EAC3I-lacking MSNs before, during and after application of baclofen (NON EGFP: n = 6; EGFP: n = 5; p = 0.48). (F) Baclofen decreases sEPSC frequency. …”

Effect of <i>LipB</i> Disruption on Lipoic Acid Levels and PDH-E2 Lipoylation by Svenja Günther (37469)

“…Wild-type LA levels are around 40 nmoles/10⁸ cells, whereas <i>LipB</i>KO lines had drastically reduced LA levels between 0.9 nmoles/10⁸ cells and 2.5 nmoles/10⁸ cells.</p><p>(B) WT 3D7 and <i>LipB</i>KO2–2 mutant were analysed for their fatty acid content. …”

Contribution of ERK isoforms to TNF-α-induced IL-8 expression. by Shinichi Namba (3350288)

“…(B) In cells pretreated with or without the ERK1/2 inhibitor FR180204 (25 μM) for 1 h and subsequently stimulated with or without TNF-α (50 ng/mL) for 5 min, TNF-α-induced ERK1/2 phosphorylation was clearly attenuated (upper panel). …”

The isolated PLCγ2 cSH2 domain affects K15-mediated signalling in a dominant negative manner. by Silvia Gramolelli (305486)

“…(B) Increasing amounts of the isolated PLCγ2 cSH2 domain decrease K15P-induced PLCγ1 phosphorylation. Western blot analysis of lysates from HeLa CNX cells co-transfected with K15 expressing construct and increasing amounts (0.5, 1, 2 μg) of vector encoding the PLCγ2 cSH2 domain (left panel) or primary HUVECs transduced with a retrovirus expressing K15 and a lentivirus expressing PLCγ2 cSH2 (right panel). …”