Image_4_Iron Overload in Patients With Heavily Transfused Sickle Cell Disease—Correlation of Serum Ferritin With Cardiac T2* MRI (CMRTools), Liver T2* MRI, and R2-MRI (Ferriscan®).... by Salam Alkindi (11601856)

“…In this evaluable cohort of 44 patients, the mean SF (±SD) reduced marginally from 4,311 to 4,230 ng/ml, mean Liver T2^* MRI dropped from 12 to 10.3 mg/gm dry weight, while the mean cardiac T2^*MRI improved from 36.8 to 39.5 ms. …”

Acute hyperphagia in <i>pmch</i>^−/− rats when newly presented with HF diet. by Joram D. Mul (221970)

“…Acute hypophagia was equal between genotypes (14±8% decrease in <i>pmch</i>^+/+ rats as compared to 17±7% decrease in <i>pmch</i>^−/− rats; *<i>P</i><0.05 versus HF days1–5, repeated-measures ANOVA with special contrast analysis; n = 6–8 per group). …”

TgNFS2 depletion impacts apicoplast-related pathways and has deleterious effects on parasite replication. by Sarah Pamukcu (11726372)

“…Scale bar represents 5 μm. DNA was labelled with DAPI. DIC: differential interference contrast.…”

NIH3T3 cells expressing Cx43dT-GFP show defects in wound closure and polarized cell movement. by Richard Francis (201117)

“…Quantitative assessment showed a significant decrease in wound closure rate in the Cx43dT-GFP expressing NIH3T3 cells at 4 and 5 hrs after wounding (G) (p<0.05). …”

Anterior segment optical coherence tomography in acute anterior uveitis by Cristiana Agra (5766521)

“…There was no significant change in temporal AC angle between visits, 44.3 ± 14.4 degrees before treatment and 44.7 ± 14.7 degrees fifteen days after (p=0.9343), and mean intraocular pressure, 10.8 ± 4.5 mmHg before treatment and 12.3 ± 3.0 mmHg fifteen days after (p=0.1874). …”

Hierarchical agglomerative cluster analysis of expression patterns of <i>Danio rerio</i> embryos tothree whole sediments and sediment extracts and 11 substances. by Kerstin Bluhm (507637)

“…<p>(Yang et al. 2007; Acrylamide: 71 mg/l; Arsenic: arsenic (III) oxide, 79 mg/l; BDE: 2,2′4,4′-tetrabromo-diphenyl ether solution 47, 38.9 mg/l; CA: 4-chloroaniline, 50 mg/l; Cd: cadmium chloride, 5 mg/l; DDT: 1,1-bis-(4-chlorphenyl)-2,2,2-trichlorethane 15 mg/l; Lead: lead (II) chloride, 2.8 mg/l; PCB: Aroclor 1254, 33 mg/l; TBHQ: tert-butylhydroquinone, 1.7 mg/l; TCDD: 2,3,7,8-tetrachlorodibenzo-<i>p</i>-dioxin, 500 ng/l; VA: valproic acid, 50 mg/l). …”

Effect of age group and TBI on change in muscle thickness in critically-ill children. by Ryan W. Johnson (6103013)

Nicotine microperfusion impairs VOR gain adaptation. by Francesca Prestori (416977)

“…Based on the polarity of the waveform of Purkinje cell activity identified in each track, the location of the granule cell layer was determined, and a dye-labelled vehicle solution with or without 5–10 ng nicotine (n = 8 and n = 7, respectively) was injected. …”

Image_8_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom... by Fen Yang (287005)

“…VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C_max, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC_0-Inf, 222.1 ng/mL h), markedly decreased distribution volume (V_z, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C_max (26.6 ng/mL) and AUC_0-Inf (95.1 ng/mL h), larger V_z (688.8 L) and CL (22.1 L/h) for VSI. …”

Image_1_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom... by Fen Yang (287005)

“…VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C_max, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC_0-Inf, 222.1 ng/mL h), markedly decreased distribution volume (V_z, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C_max (26.6 ng/mL) and AUC_0-Inf (95.1 ng/mL h), larger V_z (688.8 L) and CL (22.1 L/h) for VSI. …”

Image_6_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom... by Fen Yang (287005)

“…VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C_max, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC_0-Inf, 222.1 ng/mL h), markedly decreased distribution volume (V_z, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C_max (26.6 ng/mL) and AUC_0-Inf (95.1 ng/mL h), larger V_z (688.8 L) and CL (22.1 L/h) for VSI. …”

Image_7_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom... by Fen Yang (287005)

“…VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C_max, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC_0-Inf, 222.1 ng/mL h), markedly decreased distribution volume (V_z, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C_max (26.6 ng/mL) and AUC_0-Inf (95.1 ng/mL h), larger V_z (688.8 L) and CL (22.1 L/h) for VSI. …”

Image_3_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom... by Fen Yang (287005)

“…VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C_max, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC_0-Inf, 222.1 ng/mL h), markedly decreased distribution volume (V_z, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C_max (26.6 ng/mL) and AUC_0-Inf (95.1 ng/mL h), larger V_z (688.8 L) and CL (22.1 L/h) for VSI. …”

Image_2_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom... by Fen Yang (287005)

“…VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C_max, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC_0-Inf, 222.1 ng/mL h), markedly decreased distribution volume (V_z, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C_max (26.6 ng/mL) and AUC_0-Inf (95.1 ng/mL h), larger V_z (688.8 L) and CL (22.1 L/h) for VSI. …”

Image_4_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom... by Fen Yang (287005)

“…VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C_max, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC_0-Inf, 222.1 ng/mL h), markedly decreased distribution volume (V_z, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C_max (26.6 ng/mL) and AUC_0-Inf (95.1 ng/mL h), larger V_z (688.8 L) and CL (22.1 L/h) for VSI. …”

The effect of geniposide on Aβ_1-42-induced Bax and Bcl-2 proteins abnormally expression level. by Chunhui Zhao (309390)

“…Pretreatment of primary cortical neurons with geniposide (2.5–10 μM) could upregulate Bcl-2 expression (B), downregulate Bax expression (C) and decrease the Bax/Bcl-2 ratio (D) induced by Aβ_1–42. …”

Transgenic tobacco plants overexpressing a cold-adaptive nitroreductase gene exhibited enhanced 2,4-dinitrotoluene detoxification rate at low temperature by Doğa Selin Kayıhan (9273193)

Validation of complete model with trafficking and phosphorylation parameters. by Lindsay Wendel Clegg (754229)

“…Experimental data (black) taken from Mellberg et. al. 2006 [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004158#pcbi.1004158.ref060" target="_blank">60</a>]. TIME cells, [V] = 50 ng/mL, measurements taken at t = 5 min. …”

Replication of challenge viruses in mice immunized with the VN1203ΔNS1 virus. by Julia Romanova (225341)

“…The limit of virus detection was 1.5 log₁₀ TCID₅₀/ml. Tissues where no virus was detected were defined as 1.5 log₁₀ TCID₅₀/ml for the calculation of the mean titer.…”

Table_1_Knowledge and Response to Stroke Among Lebanese Adults: A Population-Based Survey.DOCX by Sylvia Saade (12749600)

“…Multivariable linear regression models were conducted to examine socio-demographic, social habits, and clinical factors independently associated with the SKT and the STAT scores.</p>Results<p>The mean SKT score of the participants was 9.16. 48.5% showed a poor stroke-related knowledge level and 51.5% a good knowledge level. …”