Image_2_Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients.TIF by Ebru Karasu (5158097)

“…These data suggest a novel role of the C5a-C5aR1 axis: C5a-induced MV shedding from neutrophils results in decreased C5aR1 surface expression on the one hand, on the other hand it leads to profound inflammatory signals which likely are both key drivers of the neutrophil dysfunction which is regularly observed in patients suffering from multiple traumatic injuries.…”

Image_3_Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients.TIF by Ebru Karasu (5158097)

“…These data suggest a novel role of the C5a-C5aR1 axis: C5a-induced MV shedding from neutrophils results in decreased C5aR1 surface expression on the one hand, on the other hand it leads to profound inflammatory signals which likely are both key drivers of the neutrophil dysfunction which is regularly observed in patients suffering from multiple traumatic injuries.…”

Supplementary Material for: Adult Patients with Hbs-Only Phenotype of Sickle Cell Disease have a Decreased Arginine/Asymmetric Dimethylarginine Ratio by figshare admin karger (2628495)

Theoretical Study on Reaction Scheme of Silver(I) Containing 5-Substituted Uracils Bridge Formation by Toru Matsui (1313913)

“…The whole reaction scheme is divided into the following three steps: (1) silver ion binding and deprotonation, (2) silver ion transfer, and (3) dimer formation and structural fluctuation. With a new p<i>K</i>_a computing scheme proposed in our previous studies, it is found that a silver coordination decreases the p<i>K</i>_a of <b>N</b> by 2.5–3.0 p<i>K</i>_a units, which is an important clue for silver-ion selectivity by <b>N</b>. …”

Baseline characteristics. by David Röthlisberger (17684467)

“…</p><p>Methods</p><p>We analysed data from the Leiden 85-plus Study, a prospective, population-based cohort study with adults aged ≥85 years and a 5-year follow-up. …”

Dilution coefficient (τ) at 25°C and 37°C for 5 suspending media compared to that of a physiological value of τ = 1. by Chadapust J. Sudsiri (14670602)

Image_2_Decreased Opioid Consumption in Bone Marrow Harvest Patients Using Quadratus Lumborum Blocks in a Standardized Protocol.PDF by Nicole C. McCoy (12459036)

“…The implementation group showed significantly reduced median intraoperative (20.0 mg vs. 0.0 mg; p < 0.001) and total opioid consumption (20.5 mg vs. 0.0 mg; p < 0.001). The number of patients who received any opioids decreased from 84.2% (16/19) before implementation to 23.1% (3/13) after implementation.…”

Data Sheet 1_Prehospital tranexamic acid decreases early mortality in trauma patients: a systematic review and meta-analysis.docx by Yi Li (1144)

“…Data were pooled under a random- or fixed-effects model using RevMan 5.4 with odds ratio (OR) and 95% confidence interval (CI) as the effect measures.…”

Image_1_Decreased Opioid Consumption in Bone Marrow Harvest Patients Using Quadratus Lumborum Blocks in a Standardized Protocol.PDF by Nicole C. McCoy (12459036)

“…The implementation group showed significantly reduced median intraoperative (20.0 mg vs. 0.0 mg; p < 0.001) and total opioid consumption (20.5 mg vs. 0.0 mg; p < 0.001). The number of patients who received any opioids decreased from 84.2% (16/19) before implementation to 23.1% (3/13) after implementation.…”

Image_3_Decreased Opioid Consumption in Bone Marrow Harvest Patients Using Quadratus Lumborum Blocks in a Standardized Protocol.PDF by Nicole C. McCoy (12459036)

“…The implementation group showed significantly reduced median intraoperative (20.0 mg vs. 0.0 mg; p < 0.001) and total opioid consumption (20.5 mg vs. 0.0 mg; p < 0.001). The number of patients who received any opioids decreased from 84.2% (16/19) before implementation to 23.1% (3/13) after implementation.…”

Directed Evolution of RecA Variants with Enhanced Capacity for Conjugational Recombination by Taejin Kim (472963)

“…Three of the variant proteins, RecA I102L, RecA V79L and RecA E86G/C90G were characterized based on their prominence. …”

Effect of IDO on brain 5-HT level. by Masatoshi Ohnishi (14587632)

TNF-α inhibited A549 cell viability, increased paracellular permeability, HIF-1α expression and decreased VASP expression. by Mengjie Tang (602523)

Decreased IFNγ production by BcA9 NK cells is independent of impaired MAP kinase pathway signaling or RNA instability. by Nassima Fodil (669326)

PrioV3 and ICSM35 antibodies inhibit accumulation of PrP^Sc in ScN2a cells. by Daryl Rhys Jones (351314)

“…<p>ScN2a cells were incubated for 24 hours at 37°C (5% CO₂) with 1 or 25 µg PrioV3 and ICSM35. 25 µg NCS (Normal camel serum), and BRIC126-treated as well as untreated cells were also included. …”

LARP1 regulates Netrin-1 microsomal translation. by Marie-Laure Plissonnier (337713)

“…LARP1 depletion decreases the expression of Netrin-1 protein in microsomes in Huh7.5 cells. …”

SEM images (at 100x) of (a-1) polished P110 CS and corroded in 15% HCl for 6h (a) in the absence and presence of (b) 5, (c) 6a and (d) 6b. by Ghadeer Mubarak (21567569)

Epidermal Growth Factor Receptor-Dependent Mutual Amplification between Netrin-1 and the Hepatitis C Virus by Marie-Laure Plissonnier (337713)

“…Knockdown and forced expression experiments identified the receptor uncoordinated receptor-5 (UNC5A) as an antagonist of the Netrin-1 signal, though it did not affect the death of HCV-infected cells. …”

OPTN degrades GSK3β via activating LC3-mediated autophagy. by Xiao Chen Shi (8611887)

ESX-5-dependent surface proteins of <i>M</i>. <i>marinum</i>. by Louis S. Ates (734423)

“…Shown here are only proteins with at least a five-fold decrease in spectral counts in the Δ<i>esx-5</i>::<i>mspA</i> strain. …”