Identification and Characterization of a Leoligin-Inspired Synthetic Lignan as a TGR5 Agonist by Alexander F. Perhal (20946742)

“…In this study, we identify the natural product-inspired synthetic structural analogue of leoligin, LT-188A (<b>1</b>), as a novel nonsteroidal TGR5 agonist. …”

Source data for Figs 2E, 3A, 4A and 5B. by Isabel Raposo (21615517)

“…Here, we combined computational simulations with a multimodal approach encompassing five experiments, and three different variants of classic spatial attention paradigms, to differentiate aperiodic from oscillatory-based sampling. …”

Multivariate analysis and CSF Aβ5-40/Aβ1-34. by Niklas Mattsson (144720)

“…<p>Multivariate discriminant analysis of the CSF Aβ pattern for treatment compared with placebo in dogs treated with vehicle (N = 15), NB-C8 (N = 3 at 3 h, N = 3 at 16 h) and NB-B4 (N = 5 at 6 h) (Panels a–b). …”

Decreasing leads to smaller number of spikes but does not change the resting membrane potential. by Carlos Perez (1299798)

SIRT1-mediated CRIF1 deletion-induced inflammatory cytokine and VCAM-1 expression. by Shuyu Piao (4731327)

MCP-1 expression is decreased in RPE/choroids from mice exposed to HQ. by Marianne Pons (355277)

Results of covariance analyses on the decrease of water phosphorus concentrations based on the trophic state. by Virginie Baldy (704759)

“…The first letter of the acronym corresponds to the water (A for <i>Alsatian</i> and V for <i>Vosgian</i> water), the second letter corresponds to the subpopulation (A for <i>Alsatian</i> and V for <i>Vosgian</i> subpopulation) e.g. …”

<i>Eh</i> promotes the degradation of cullin-1, cullin-5, cullin-4A and cullin-4B from macrophages. by Attinder Chadha (11414273)

Subjects:

THC reversed PCP-induced decrease in dopamine neuron population activity in the VTA. by Alexandre Seillier (8566116)

DXM administration increases time spent in the wake state and decreases that in NREM sleep. by Tomonobu Kato (17684578)

Pretreatment of fibroblasts with 1.2 mM H₂O₂ for 30 minutes significantly decreased relative fibroblast migration speed to 63.5±4.2% (p = 4.28–07) compared to... by Andrew Mamalis (5665591)

Earlier Migration Timing, Decreasing Phenotypic Variation, and Biocomplexity in Multiple Salmonid Species by Ryan P. Kovach (103840)

“…<div><p>Climate-induced phenological shifts can influence population, evolutionary, and ecological dynamics, but our understanding of these phenomena is hampered by a lack of long-term demographic data. We use a multi-decade census of 5 salmonid species representing 14 life histories in a warming Alaskan stream to address the following key questions about climate change and phenology: How consistent are temporal patterns and drivers of phenology for similar species and alternative life histories? …”

Decreased tubulin acetylation in kalirin-7 expressing cells under TSA treatment. by Yu-Chun Tsai (110682)

“…<p>(A, B) An interaction of FLAG-kalirin-7, V5-synphilin-1 and HA-HDAC6 was examined by co-immunoprecipitation experiments. 24 h after transfection, HEK293 cells were lysed and 500 µg of protein lysates were subjected to immunoprecipitation with anti-FLAG or anti-V5 conjugated agarose beads, respectively. …”

StcE decreases neutrophil random migration via impaired uropod retraction. by Rose L. Szabady (266854)

The introduction of mutualisms into assembled communities increases their connectance and complexity while decreasing their richness. by Gui Araujo (22170819)

“…The connectance of invading species was drawn from a uniform distribution between 0.05 and 0.5. In speciation, offspring species had up to 5 interactions differing from the parent species, chosen randomly (, see Methods). …”

Effects of Fluid Aging and Reservoir Temperature on Waterflooding in 2.5D Glass Micromodels by Duy Le-Anh (8722380)

“…To study improved oil recovery (IOR) via laboratory experiments at the pore scale, we performed waterflooding experiments in a glass 2.5D micromodel (dual depth: 12 and 27 μm) with crude oil (CRO) and brines of variable compositions at temperatures ranging from 22 °C (room temperature) to 90 °C. …”

Effects of Fluid Aging and Reservoir Temperature on Waterflooding in 2.5D Glass Micromodels by Duy Le-Anh (8722380)

“…To study improved oil recovery (IOR) via laboratory experiments at the pore scale, we performed waterflooding experiments in a glass 2.5D micromodel (dual depth: 12 and 27 μm) with crude oil (CRO) and brines of variable compositions at temperatures ranging from 22 °C (room temperature) to 90 °C. …”

A: Bacteria species/ASVs exhibiting a significant change in relative abundance after exposure to sodium sulfite. by Sally V. Irwin (4521733)

Bm-UGT expression knockdown decreases worm motility, microfilariae release, and metabolism. by Alexander F. Flynn (7377575)

Expression of SPDEF in prostate adenocarcinoma cells decreased prostate carcinogenesis in orthotopic model. by Xin-Hua Cheng (154368)

“…<b>A</b>. SPDEF decreased the growth of prostate tumors in orthotopic model. …”