GluN2A(D731N) reduces the agonist potency. by Kai Gao (120150)

“…<p>(<b>A,B</b>) Representative TEVC recordings obtained from oocytes expressing WT GluN1/GluN2A (WT 2A) receptors (<b>A</b>) and GluN1/GluN2A(D731N) (2A-D731N) receptors (<b>B</b>) in which the currents were evoked by increasing concentrations (μM) of glutamate (in the presence of 100 μM glycine) at the holding potential of -40 mV. …”

S100A9 treatment decreases the secretion of pro-inflammatory cytokines (A) 5 days after LPS injection, sera were collected and tested for IL-6 by ELISA. by Annabelle Cesaro (112070)

FLIM-FRET measurements with KIRIN1 sensor detects relative changes in intracellular K⁺. by Xiaowen Jiang (8291814)

“…<b>(C)</b> FLIM-FRET measurements for intracellular K⁺ levels in HEK293 Cells transfected with the CMV:KIRIN1 sensor and either CMV:Kcnk5bS345A-mCherry, CMV:Kcnk5bWT-mCherry, or CMV:Kcnk5bS345E-mCherry. …”

RNF5 depletion suppresses PEL xenograft tumor growth and decreases the levels of cell cycle gene expression and hedgehog signaling in tumors. by Xiaojuan Li (351842)

OCA alone markedly decreases and combined with Gemcitabine or Cisplatin abrogates growth of iCCA xenografts. by S. Di Matteo (6260417)

“…Treatment with Gemcitabine or Cisplatin alone decreased tumor volume to a higher (p < 0.05) extent than OCA alone. …”

Decreased serum IgG2a, IgG2b and IgG3 levels in IRF5-deficient MRL/lpr mice. by Kei Yasuda (606333)

CoREST1 and CoREST2, but not CoREST3 decrease during cortical neurons maturation. by Julián Esteban Sáez (760988)

Cisd2KO mice exhibit cardiac electromechanical dysfunctions that are similar to those observed in the naturally aged WT mice. by Chi-Hsiao Yeh (7474556)

“…Mouse number <i>n</i> ≥ 5 for each group. Values for each data point can be found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000508#pbio.3000508.s001" target="_blank">S1 Data</a>. 3M, 3 months old; 6M, 6 months old; 26M, 26 months old; APC, atrial premature complex; AV, atrioventricular; Cisd2KO, CDGSH iron-sulfur domain-containing protein 2 KO; ECG, electrocardiography; KO, knockout; MRI, magnetic resonance imaging; QTc, corrected QT; VPC, ventricular premature complex; WT, wild type.…”

Typical tracing of the effect of i.a. endothelin 0.5 10⁻⁵ M on arterial pressure in rats: the initial transient decrease of arterial pressure is followed by a sustained increase (Fig 2A). by Matthieu Roustit (315980)

Decreased production of highly reactive oxygen species production induced by complement-mediated phagocytosis in Rab27a-knockdown cells. by Tatsumi Kawakami (505540)

Mean-difference plots by country: Countries with decreased variance and decreased mean height (95% confidence interval shaded). by Jewel Gausman (5210969)

Pairwise correlations of excitatory neurons in APP/PS1 mice are decreased in dCA1, but increased in vCA1. by Udaysankar Chockanathan (18510288)

Analysis of WT and <i>Abl</i> neuronal growth at RT and HT. by Lijuan Liu (136685)

“…Neurons in Abl cultures show a greater number of filopodia at RT than WT but show a significant decrease in filopodial numbers following HT incubation (cell clusters numbers: WT RT, 74; WT HT, 66; Abl RT, 72; Abl HT, 102, respectively, **p<0.01, unpaired T-test). …”

Decreased diaphragm muscle axonal branching distance, bifurcations and neuromuscular junctions in GAD67-deficient (−/−) E18.5 mice. by Matthew J. Fogarty (283288)

“…D shows a significantly decreased medial and lateral bifurcation number (mean ± SEM) in GAD67-deficient mice compared to wild type (<i>n</i> = 10, **<i>P</i><0.01, ***<i>P</i><0.001, unpaired <i>t</i> test). …”

V3Nter decreases colony formation and induces tumor cell death in HCT116 and HepG2 cells. by Delphine Quélard (43727)

Inhibition of ILK Decreases Bipolar and Multipolar Cytokinesis while Increasing Survival of Multinucleated Cells. by William K. A. Sikkema (574881)

Cycloheximide (CHX) treatment decreases production of rRNA transcripts by POLR1 and POLR3. by Martin Selinger (3195987)

“…<p>(A) DAOY cells were treated with CHX (100 μg/ml) for either 6 or 14 hours; for metabolic RNA labelling, 5-EU was added 2 hours before the sample collection. …”

Influence of ghrelin treatment (0.5 μg/g BW, twice a day, intraperitoneal (ip.)) on survival, body weight and body temperature within 48 hours after cecal ligation and puncture (CL... by Daniel Siegl (717509)

Resveratrol decreases cytokine–induced pro-inflammatory mediators production more efficiently than 5-ASA, in HT-29 cells. by Diana Serra (455187)

Knockdown of UPF1 increases the expression level and prolongs the decay rate of GAS5, and decreases the expression of glucocorticoid-responsive genes. by Hidenori Tani (169942)