An autophagy-inducing compound ML246 reduces amyloid load in an autophagy-dependent manner in vitro and in vivo. by Altea Rocchi (3278457)

I-O functions in CA1 neurons in slices from TG and WT mice 9 months post-irradiation. by Emil Rudobeck (4630822)

“…<p>(A) Radiation exposure did not significantly affect the presynaptic fiber volleys (pV) in either in TG or in WT mice. …”

ULK1 and ATG13 phosphorylation sites in mitosis by CDK1/cyclin B. by Zhiyuan Li (205620)

Blocking CD88 decreased ANCA antigen translocation, ANCA-induced respiratory burst and degranulation in C5a-primed neutrophils. by Jian Hao (160736)

“…C and D: blocking CD88 decreased C5a-primed neutrophils for ANCA-induced respiratory burst. …”

Hel2 and Asc1 attenuate gene expression from stall-containing mRNAs only at high initiation rates. by Heungwon Park (3859507)

Effect of HpTx-2 on K⁺ current from isolated WT and Kv4.2-/- cardiomyocyte. by Jie Liu (15128)

“…<p>(A) This panel illustrates representative K^<b>+</b> current traces recorded from isolated WT cardiomyocyte under baseline (dark) conditions and after the addition of 5 μM HpTx-2 (red), a high-selective Kv4.x channel blocker. …”

Klf5 and eIF5a suppress Ang II–induced expression of NOX1 in VSMCs. by Dong Ma (584680)

Subjects:

Phlorizin decreased renal GTTR uptake, and increased serum drug levels <i>in vivo</i>. by Meiyan Jiang (438439)

<i>prx-5/6</i> mutations likely cause a decrease in mmBCFA degradation. by Rencheng Wang (463927)

“…<i>elo-5</i>(<i>lf</i>)<i>; Ex</i>[<i>elo-6</i>] is a transgenic strain that significantly overexpressed the <i>elo-6</i> gene and was not sufficient to suppress the L1 arrest phenotype of <i>elo-5</i>(<i>lf</i>). …”

HAstV-1 infection leads to a decrease in epithelial markers while increasing mesenchymal markers. by Virginia Hargest (12447014)

CYP3A94 activity is significantly increased in V79-CYP3A94/DD-POR cells, but decreases after incubation with Shield-1. by Ramona Dettwiler (664360)

The <i>TgCRT</i>-deficient parasites displayed a swollen vacuole and a disrupted endolysosomal system. by L. Brock Thornton (6808385)

“…Scale bar = 5 μm. (B) The swollen subcellular structure indicated by the arrow was also observed in pulse-invaded <i>Δcrt</i> parasites and colocalized with a major luminal peptidase of the VAC, cathepsin L-like protease (TgCPL). …”

Gut richness and diversity decrease significantly by week 5 of chemoradiotherapy. by Molly B. El Alam (10231830)

Light and electron microscopic distributions of Vpu-APEX2 and mutants A18H, AAA/F, and S52,56N. by Charlotte A. Stoneham (10819125)

5S rDNA transgenes show preferential association with the nucleolus and decreased transcription of a reporter gene. by Andrew M. Fedoriw (187310)

BoNT/A (3.5 U/kg) decreases orofacial formalin-induced dural extravasation. by Boris Filipović (336089)

Differentially regulated genes in cells with increased or decreased expression of miR-106a-5p. by Feng Zhi (294362)

“…(C) A Venn diagram of the overlap of altered genes with increased or decreased miR-106a-5p expression. …”

Lysine Mutation of the Claw-Arm-Like Loop Accelerates Catalysis by Cellobiohydrolases by Zhiyou Zong (7336904)

“…Experimental validation was performed using the full-length wild-type (WT) of <i>Te</i>Cel7A and its mutants, recombinantly expressed in <i>Pichia pastoris</i>, to degrade the substrates. …”

Quantitative Proteomics Reveal an Altered Pattern of Protein Expression in Brain Tissue from Mice Lacking GPR37 and GPR37L1 by TrangKimberly Thu Nguyen (8418141)

“…One of the most decreased proteins in the DKO versus WT brain tissue was S100A5, a calcium-binding protein, and the reduction of S100A5 expression in KO brain tissue was validated via Western blot. …”

Quantitative Proteomics Reveal an Altered Pattern of Protein Expression in Brain Tissue from Mice Lacking GPR37 and GPR37L1 by TrangKimberly Thu Nguyen (8418141)

“…One of the most decreased proteins in the DKO versus WT brain tissue was S100A5, a calcium-binding protein, and the reduction of S100A5 expression in KO brain tissue was validated via Western blot. …”