Image_5_Myricetin, the Main Flavonoid in Syzygium cumini Leaf, Is a Novel Inhibitor of Platelet Thiol Isomerases PDI and ERp5.tif by Renato Simões Gaspar (8384040)

“…Additionally, myricetin is a novel inhibitor of ERp5 and PDI, unveiling a new therapeutic perspective for the treatment of thrombotic disorders.…”

Table_5_Two DNA Methyltransferases for Site-Specific 6mA and 5mC DNA Modification in Xanthomonas euvesicatoria.XLSX by Hye-Jee Park (3594245)

“…Xe(XvDMT2) was more tolerant to EtOH than Xe(XvDMT1), which had enhanced tolerance to sorbitol but decreased tolerance to polymyxin B. Using single-molecule real-time sequencing and methylation-sensitive restriction enzymes, we successfully predicted putative motifs methylated by XvDMT1 and XvDMT2, which are previously uncharacterized 6mA and 5mC DNA MTases, respectively. …”

m⁶A mRNA methylation controls autophagy and adipogenesis by targeting <i>Atg5</i> and <i>Atg7</i> by Xinxia Wang (301455)

“…Mechanistically, knockdown of FTO, a well-known m⁶A demethylase, decreased the expression of ATG5 and ATG7, leading to attenuation of autophagosome formation, thereby inhibiting autophagy and adipogenesis. …”

Additional file 3 of ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy by Lihong Lu (10532648)

Pharmacological targeting of polyamine and hypusine biosynthesis reduces tumour activity of endometrial cancer by Hong Im Kim (4686187)

“…Spermidine is required for the hypusine-dependent activation of eukaryotic translation initiation factors 5A1 (eIF5A1) and 5A2 (eIF5A2) and connects the MYC/ODC-induced deregulation of spermidine to eIF5A1/2 protein translation, which is increased during cancer cell proliferation. …”

Mitochondrial damage is a key event in the mechanism of oncosis in skeletal muscle cells. by Chengcheng Li (2591632)

Data_Sheet_1_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.DOCX by Ai Qing Yu (9774356)

“…Decrotonylation of PHF5A K25 contributed to decreased CDK2 expression by retained intron (RI)-induced abnormal AS, thereby accelerating fibroblast senescence, and supporting a key role of PHF5A K25 decrotonylation in aging. …”

Data_Sheet_2_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.XLS by Ai Qing Yu (9774356)

“…Decrotonylation of PHF5A K25 contributed to decreased CDK2 expression by retained intron (RI)-induced abnormal AS, thereby accelerating fibroblast senescence, and supporting a key role of PHF5A K25 decrotonylation in aging. …”

Data_Sheet_3_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.XLSX by Ai Qing Yu (9774356)

“…Decrotonylation of PHF5A K25 contributed to decreased CDK2 expression by retained intron (RI)-induced abnormal AS, thereby accelerating fibroblast senescence, and supporting a key role of PHF5A K25 decrotonylation in aging. …”

WBC-thrombus interaction affects the instantaneous mean blood velocity upstream of the thrombogenic site. by He Li (176971)

Continued. by Zen Kouchi (14898435)

“…PARG1 I845V mutant complex was theoretically deduced to disorganize RhoA interfaces and T622M mutation decreased the substrate affinity to 80% of that of WT PARG1 complex. …”

Kcnk5b activity induces IP₃R-mediated Ca²⁺ release from the ER. by Xiaowen Jiang (8291814)

A new resource allocation model partitions the genome in five expression sectors. by Mónica Chagoyen (4253800)

“…<p><b>A)</b> Top. Resource allocation model (Model 1) based on three sectors in which the expression of their constituent genes increases (positive genes, blue), decreases (negative genes, red), or remains constant (invariant genes, brown) with increasing growth rate. …”

The R code that was used to graph the acid dissociation data for H₃As(V)O₄ in S4 File. by Seth H. Frisbie (7821866)

Quantifying the Contribution of Statins to the Decline in Population Mean Cholesterol by Socioeconomic Group in England 1991 - 2012: A Modelling Study by Chris Kypridemos (719751)

“…In our ‘no statins’ scenario we predicted a mean total cholesterol of 5.36 mmol/L (95% CI: 5.33-5.40) for 2011-12. …”

Steady state voltage, concentrations and electrochemical potentials for the nanopore in Fig 5a. by Liesbeth van Oeffelen (511929)

“…<p>The values shown are those in a plane through the axis of the nanopore, with <i>V</i>_<i>L</i>−<i>V</i>_<i>R</i> = 0.5 V and a surface charge density of −50mC/m². …”

Analysis of correlations between identified metabolites and steroid hormones with general characteristic data. by Saoraya Chanmuang (13242534)

Plot of the density profiles in the (a) stable and (b) expansion regions for the potential (5) by J B Sudharsan (557453)

“…</strong> Plot of the density profiles in the (a) stable and (b) expansion regions for the potential (<a href="http://iopscience.iop.org/0953-4075/46/15/155302/article#jpb466473eqn05" target="_blank">5</a>).…”

Pim1 inhibition results in a reduced visual response at 5 dpf. by Jun Yin (94374)

“…Pim1 inhibitors were dissolved in 0.1% DMSO at all concentrations except the 100 µM concentration which was dissolved in 1% DMSO. (B) The ERG a-wave and b-wave are significantly decreased in 100 µM Pim1 inhibitor 2 treated fish. …”

PM2.5 associates with blood pressure: a Mendelian randomization analysis by Minghui Bao (767132)

“…<p>The relationship between fine particulate matter (PM2.5) and blood pressure (BP) is a controversial issue. …”