Decreased hypotaurine levels within cells lacking the ADO gene in U251 cells. by Hong Tian (169626)

Decreased remyelination initiation is observed in Scribble cKO mice following focal demyelination in corpus callosum. by Andrew A. Jarjour (343100)

“…In the contralateral (unlesioned) hemisphere (CL), no difference was seen in the proportion of axons in the corpus callosum that were myelinated in Scribble cKO compared to wild-type animals (A–C). Fewer remyelinated axons were observed in corpus callosum in the lesion area in Scribble cKO mice (E) relative to controls (D) as quantified in F; 0.4–0.5 μm: WT = 80.0% ± 9.8%, cKO = 41.3% ± 8.9% myelinated; 0.5–0.6 μm: WT = 79.4% ± 6.3%, cKO = 41.5% ± 9.5% myelinated; 0.6–0.7 μm: WT = 91.6% ± 3.0%, cKO = 44.3% ± 8.7% myelinated; >0.7 μm: WT = 92.7% ± 1.9%, cKO = 47.9% ± 2.5% myelinated. …”

GluA1KO mice mimic the EAC3I mice decrease in sEPSC frequency. by Jason R. Klug (132807)

Demographics and baseline characteristics of the safety population. by Rahsan Erdem (11726357)

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iOWH032 inhibits cholera toxin-induced secretion in a mouse closed-loop model. by Rahsan Erdem (11726357)

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Grading of stool consistency and diarrhea severity. by Rahsan Erdem (11726357)

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Secondary efficacy endpoints for the modified intent-to-treat population. by Rahsan Erdem (11726357)

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Study drug–related treatment-emergent adverse events by system organ class and preferred term in the safety population. by Rahsan Erdem (11726357)

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Source data for Fig 1. by Rahsan Erdem (11726357)

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Diarrheal stool output rate overall and by blood type status in the modified intent-to-treat population. by Rahsan Erdem (11726357)

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Source data for S1 and S2 Figs. by Rahsan Erdem (11726357)

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Source data for Fig 2. by Rahsan Erdem (11726357)

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Consolidated Standards for Reporting of Trials flow diagram. by Rahsan Erdem (11726357)

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iOWH032 inhibits cholera toxin-induced fecal output in a cecectomized rat model. by Rahsan Erdem (11726357)

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Source data for Fig 3. by Rahsan Erdem (11726357)

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Scatterplot of iOWH032 plasma concentrations versus diarrheal stool output rate. by Rahsan Erdem (11726357)

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Reverse cumulative distribution plot for diarrheal stool output rate overall in the modified intent-to-treat population. by Rahsan Erdem (11726357)

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Diarrheal disease severity by treatment group for the modified intent-to-treat population. by Rahsan Erdem (11726357)

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Absence of PICALM results in a decreased rate of internalization and increased cell surface expression of TfR in MEFs. by Paula B. Scotland (138601)

PGC-1β KO mice show a specific decrease in Mfn2 expression in skeletal muscle. by Marc Liesa (35879)