New Dual P‑Glycoprotein (P-gp) and Human Carbonic Anhydrase XII (hCA XII) Inhibitors as Multidrug Resistance (MDR) Reversers in Cancer Cells by Laura Braconi (8679744)

“…Indeed, hCA XII modulates the efflux activity of P-gp and the inhibition of hCA XII reduces the intracellular pH, thereby decreasing the ATPase activity of P-gp. All compounds showed inhibitory activities on P-gp and hCA XII proteins taken individually, and many of them displayed a synergistic effect in HT29/DOX and A549/DOX cells that overexpress both P-gp and hCA XII, being more potent than in K562/DOX cells overexpressing only P-gp. …”

DataSheet1_Silver nanoparticle interactions with glycated and non-glycated human serum albumin mediate toxicity.PDF by Hee-Yon Park (14687089)

Generation of Arid3b conditional knockout system. by Jeffrey L. Kurkewich (3044211)

Table5_The IDI1/SREBP2 axis drives intrahepatic cholestasis and is a treatment target of San-Huang-Cai-Zhu formula identified by sequencing and experiments.XLSX by Junbin Yan (10166689)

Table_5_Voluntary Exercise-Induced Activation of Thyroid Axis and Reduction of White Fat Depots Is Attenuated by Chronic Stress in a Sex Dimorphic Pattern in Adult Rats.pdf by Marco Antonio Parra-Montes de Oca (6880589)

Data_Sheet_5_Molecular Signals of Heterogeneous Terrestrial Environments Identified in Dissolved Organic Matter: A Comparative Analysis of Orbitrap and Ion Cyclotron Resonance Mass... by Carsten Simon (5784356)

Rli27 is necessary for upregulation of Lmo0514 protein levels in intracellular bacteria by a mechanism that involves interaction with the <i>lmo0514</i> long 5′-UTR isoform. by Juan J. Quereda (651911)

“…<p>(A) Real-time qPCR assays showing no changes in relative levels of the <i>lmo0514</i> ORF (fragment amplified with Lmo0514-F and Lmo0514-R primers) or the isoform bearing the long 5′-UTR (fragment amplified with UTR-B and UTR-1R primers) in intracellular bacteria that lack Rli27 or are defective for the <i>rli27</i>-flanking <i>lmo0411</i> gene. …”

DUOX activation upon HPx1 silencing and hierarchical mode of activation of innate immunity in the mosquito midgut. by Octavio A. C. Talyuli (4285141)

MXene-Reinforced Antifreezing Conductive Eutectogel with Enhanced Sensing Sensitivity for Low-Temperature Wearable Sensors by Aobo Ren (9651579)

“…However, the water in hydrogels is prone to freezing at low temperatures, decreasing flexibility and sensing performance. In this work, a dual-network eutectogel composed of poly­(vinyl alcohol) and poly­(acrylic acid) is prepared by using deep eutectic solvent (DES) and MXene as the antifreezing medium and conductive component, respectively. …”

Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia by J. Pedro Fernández-Murray (2182594)

“…<div><p>Sideroblastic anemias are acquired or inherited anemias that result in a decreased ability to synthesize hemoglobin in red blood cells and result in the presence of iron deposits in the mitochondria of red blood cell precursors. …”

The relationship between ecosystem multifunctionality and bacterial Chao1 estimated richness. by Melissa S. Shinfuku (19942206)

The COVID pandemic in Chile: Own construction using administrative data from the Ministry of Health. by Raimundo Atal (18272064)

A small proportion of Talin molecules transmit forces at developing muscle attachments in vivo by Sandra B. Lemke (6519788)

“…Concomitantly, the Talin concentration at attachment sites increases 5-fold as quantified by fluorescence correlation spectroscopy (FCS), suggesting that only a small proportion of Talin molecules are mechanically engaged at any given time. …”

Main results including COVID-19 deaths. by Raimundo Atal (18272064)

<i>De Novo</i> B cell production is critically impaired in Arid3b null mice. by Jeffrey L. Kurkewich (3044211)

Decreased early CD4+ and CD8+ T cell expression of TNFα in the lungs and spleens of IFNγ-KO mice infected with the epidemic strain <i>M. massiliense</i> CRM-0019. by Shaobin Shang (205922)

“…Panels B and C show decreased CD4+ and CD8+ T cell expression of TNFα in the lungs (A) and spleens (B) of mice infected with the epidemic strain CRM-0019 compared to CIP 108297 (± SEM, n = 5). …”

Internet-Delivered Cognitive Behavioral Therapy to Treat Insomnia: A Systematic Review and Meta-Analysis by Michael Seyffert (849995)

“…Internet-delivered cognitive behavioral therapy resulted in a decrease in the insomnia severity index by 4.3 points (95% CI: -7.1, -1.5; p = 0.017) compared to control. …”

Erythroid and myeloid progenitor lineages are unperturbed in <i>Arid3b</i>^<i>-/-</i> mice. by Jeffrey L. Kurkewich (3044211)

Table_5_Analysis of LINE1 Retrotransposons in Huntington’s Disease.XLSX by Lavinia Floreani (11946644)

Analysis of T cell population in thymus of <i>Arid3b</i>^<i>-/-</i> mice. by Jeffrey L. Kurkewich (3044211)