Deformative Transition of the Menschutkin Reaction and Helical Atropisomers in a Congested Polyheterocyclic System by Yung-Yu Chang (1724704)

“…Conformational flexibility in dipyridylethene <b>9</b> is clearly shown by its complexation with BH₃ to form helical atropisomers (<i>P,P</i>/<i>M,M</i>)-<b>10</b>. The p<i>K</i>_a values of the conjugate acids of <b>1A</b> and <b>9</b> in acetonitrile were determined to be 4.65 and 5.07, respectively, which are much smaller compared to that of pyridine <b>14a</b> (p<i>K</i>_a = 12.33), implying that the basicity, nucleophilicity, and amine alkylation rates of <b>1A</b> and <b>9</b> are markedly decreased by the severe steric hindrance of the flanking phenyl rings in the polyheterocycles.…”

The association between previous and future severe exacerbations of chronic obstructive pulmonary disease: Updating the literature using robust statistical methodology by Mohsen Sadatsafavi (63962)

“…<div><p>Background</p><p>There is minimal evidence on the extent to which the occurrence of a severe acute exacerbation of COPD that results in hospitalization affects the subsequent disease course. …”

Influence of natural gas composition on adsorption in calcite Nanopores: A DFT study by Elbashier E.

“…The nanopores absorbed up to 28 and 24 molecules of CH4 and CO2, respectively, and the adsorption energy decreased to −0.0062 and −0.0075 eV/Å2 for each. Although the nanopore was filled spatially by the molecules, its surface still has an affinity to absorb more gas molecules energetically. …”
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Pyrvinium inhibits WNT signaling in a CK1α dependent manner. by Bin Li (39349)

“…<p><b>A</b>. The expression of the WNT target gene: <i>AXIN2</i> was determined from NIH 3T3 cells expressing control or <i>CK1α</i>-specific shRNAs. …”

A comparison of viral dsRNAs and poly(I:C) for activation of TLR3. by Yvonne Lai (199718)

“…B) A comparison of the effects of viral dsRNAs and poly(I:C) in HEK 293T cells transfected to express the WT TLR3 or a ligand-binding mutant, H539E. …”

Genetic variance of a trait under stabilizing selection with multi-population demography. by Aaron P Ragsdale (20968248)

“…In Deme 2, <i>V_G</i> decreases due to their population size reduction. …”

Association between breastfeeding and eczema during childhood and adolescence: A cohort study by Jingying Wang (4458820)

Expression pattern of a <i>puc</i> reporter line in the central brain. by David Kapfhamer (295513)

“…<p><b><i>A</i></b>, Rescue of decreased <i>puc¹/+</i> ethanol-induced locomotor stimulation in the <i>NP1311</i> expression pattern. …”

Supplementary Material for: Trends in Literature on Cerebral Bypass Surgery: A Systematic Review by Grüter B.E. (11166240)

“…<b><i>Methods:</i></b> A systematic literature research was conducted using PubMed, Web of Science, EMBASE, and SCOPUS databases. …”

Epidemiology of harmful use of alcohol in Nigeria: a systematic review and meta-analysis by Davies Adeloye (589375)

“…However, actual age-adjusted prevalence of harmful use of alcohol in Nigeria decreased from 38.5% to 32.6% over the twenty-year period.…”

Down-regulation in antimicrobial and absorption expression programs. by Noam Cohen (319186)

“…Black dashed lines represent mean values; white dots represent median values of 5 repeats of at least 3 individual FAE from 2 mice. …”

Ligand-dependent stability of a 240 kDa protein can be probed by FASTpp. by David P. Minde (304427)

“…A gradual decrease in the band intensity at higher temperatures indicates unfolding. …”

Effect of using Cement Kiln Dust as a nano-material on the strength of cement mortars by Alnahhal, Wael

“…The CKD was milled up to 4 hours in a planetary ball mill. In addition to the control cement mortar mixture with 0% CKD, a total of 28 concrete mortar mixtures were prepared with four different replacement percentages of nano-CKD (5, 10, 15, and 20 %), and seven different milling times (1, 1.5, 2, 2.5, 3, 3.5, and 4 hours). …”
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Table_1_Regular Low-Intensity Exercise Prevents Cognitive Decline and a Depressive-Like State Induced by Physical Inactivity in Mice: A New Physical Inactivity Experiment Model.doc... by Jimmy Kim (12509761)

“…In addition, regular low-intensity exercise, 30 min of treadmill running at a 5–15 m/min treadmill speed 3 days per week, prevented cognitive decline and the onset of a depressive-like state caused by physical inactivity. …”

SIRT1 preserves dendritic integrity in hippocampal neurons challenged with Aβ fibrils. by Juan F. Codocedo (304388)

“…(<b>B,C</b>) Normalized TDBTN (B) and coverage area (C) of experimental conditions shown in (A). (<b>D</b>) Sholl analysis of transfected neurons: GFP (black circles), GFP + Aβ 5 µM (with circle), SIRT1/GFP + Aβ 5 µM (red triangle), SIRT1H363Y/GFP + Aβ 5 µM (blue triangle). …”

Data_Sheet_1_A scientifically validated combination of garcinol, curcuminoids, and piperine for mild to moderate nonalcoholic steatohepatitis patients—results from a randomized, do... by Muhammed Majeed (659312)

“…</p>Methods<p>The patients received one tablet (450 mg) of GCP containing garcinol-50 mg, curcuminoids −250 mg and piperine 5 mg or a placebo (450 mg of microcrystalline cellulose) twice daily for 90 days. …”

Ocean acidification modulates expression of genes and physiological performance of a marine diatom by Yahe Li (564095)

“…The expression of the genes encoding fucoxanthin chlorophyll <i>a</i>/<i>c</i> protein (lhcf type (<i>fcp</i>)), mitochondrial ATP synthase (<i>mtATP</i>), ribulose-1, 5-bisphosphate carboxylase/oxygenase large subunit gene (<i>rbcl</i>) and NADH dehydrogenase subunit 2 (<i>ndh</i>2), were down-regulated during the first four days (< 8 generations) after the cells were transferred from LC (cells grown under ambient air condition; 390 μatm; pH_nbs 8.19) to OA conditions, with no significant difference between LC and HC treatments with the time elapsed. …”

Characterization of JTA009, a novel anti-human ICOS mAb by Manabu Kawamoto (18939)

“…</p><p>Published online 22 Mar 2006</p><p>PMCID:PMC1526621.</p><p></p> JTA009, a fully human anti-human ICOS mAb, has greater avidity than SA12. …”

Dengue seroprevalence in a cohort of schoolchildren and their siblings in Yucatan, Mexico (2015-2016) by Norma Pavía-Ruz (5999918)

“…</p><p>Methods</p><p>A cohort of school children and their family members was randomly selected in three urban areas with different demographic, social conditions and levels of transmission. …”

Extended use of poultry manure as a nutrient source for flood-irrigated rice crop by Fabiana Schmidt (8465247)

“…<div><p>Abstract: The objective of this work was to evaluate changes in the soil chemical properties, nitrogen use efficiency, and grain yield of flood-irrigated rice fields after the addition of poultry manure during five years. Trials were carried out in a randomized complete block design, with three replicates. …”