Identification and Functional Validation of Caldesmon as a Potential Gastric Cancer Metastasis-associated Protein by Qian Hou (672015)

“…In total, 641 proteins were identified with at least a 95% confidence. Using cutoff values of >1.5 and <0.67, 19 proteins were found to be up-regulated and 34 were down-regulated in the metastatic versus primary gastric cancer cell lines respectively. …”

Supplementary Material for: Protective effects of Xanthohumol against diabetic nephropathy in a mouse model by Li F. (3206265)

“…Introduction: Diabetic nephropathy (DN) is a long-term loss of renal function occurring in the diabetic patients, leading to 5 million deaths in 2015, and this number is dramatically growing annually. …”

Mucosal-Associated Invariant T Cell Is a Potential Marker to Distinguish Fibromyalgia Syndrome from Arthritis by Chie Sugimoto (245505)

“…</p><p>Results</p><p>There was a decrease in the MAIT cell population in FMS, RA, and SpA compared with HD. …”

Cholesteryl Ester Transfer Protein Inhibitors in the Treatment of Dyslipidemia: A Systematic Review and Meta-Analysis by Chuanwei Li (477417)

“…Our meta-analysis revealed that CETP inhibitors increased the HDL-c levels (n = 2826, p<0.00001, mean difference (MD)  = 20.47, 95% CI [19.80 to 21.15]) and total cholesterol (n = 3423, p = 0.0002, MD = 3.57, 95%CI [1.69 to 5.44] to some extent combined with a reduction in triglyceride (n = 3739, p<0.00001, MD = −10.47, 95% CI [−11.91 to −9.03]) and LDL-c (n = 3159, p<0.00001, MD = −17.12, 95% CI [−18.87 to −15.36]) irrespective of mono-therapy or co-administration with statins. …”

Analysis of a presynaptic component to C-fiber-evoked LTP on spinal-PAG projection neurons. by Ceng Luo (179354)

“…<p>(A, B) Activation of C-nociceptors potentiates synaptic transmission by decreasing the rate of synaptic failures via activation of presynaptic PKG-I. …”

Supplementary Material for: Impact of Baroreflex Activation Therapy on Renal Function - A Pilot Study by Wallbach M. (2861837)

“…Proteinuria and albuminuria decreased from a median of 283.9 and 47.7 to 136.5 (p = 0.01) and 45.0 mg/g creatinine (p = 0.01) with pronounced effects in higher CKD stage III + IV compared to I + II (p < 0.01). …”

Decoding dynamic patterns of neural activity using a ‘biologically plausible’ fixed set of weights by Ethan Meyers (495583)

Blindness and Glaucoma: A Multicenter Data Review from 7 Academic Eye Clinics by Luca Rossetti (711357)

“…During follow-up the IOP decreased by 14% in these eyes but MD deteriorated by 1.1±3.5 dB/year, which was 5-fold higher than controls (0.2±1.6 dB/year). …”

A Novel Missense Mutation, I890T, in the Pore Region of Cardiac Sodium Channel Causes Brugada Syndrome by Anna Tarradas (105463)

“…Sodium currents were studied using standard whole cell patch-clamp protocols and immunodetection experiments were performed using an antibody against human Na_v1.5 channel. A marked decrease in current density was observed in cells expressing the I890T channel (from −52.0±6.5 pA/pF, <em>n</em> = 15 to −35.9±3.4 pA/pF, <em>n</em> = 22, at −20 mV, WT and I890T, respectively). …”

Per- and polyfluoroalkyl substances impact human spermatogenesis in a stem-cell-derived model by Alyse N. Steves (5409011)

A J-Like Protein Influences Fatty Acid Composition of Chloroplast Lipids in Arabidopsis by Imad Ajjawi (200926)

“…T-DNA mutants in the poorly annotated <em>Arabidopsis thaliana</em> gene At1g08640 were identified as containing moderately high levels (50–100%) of 16∶1Δ7 and 18∶1Δ9 leaf fatty acids and subtle decreases (5–30%) of 16∶3 and 18∶3 (<a href="http://www.plastid.msu.edu/">http://www.plastid.msu.edu/</a>). …”

Antinociceptive and anti-inflammatory activities of a triterpene-rich fraction from Himatanthus drasticus by S.C.X. de-Almeida (6720584)

“…Indomethacin, used as reference, inhibited the paw edema by 59% at the same time-point. In the formalin test, FJNB inhibited the 1st phase by 27, 49, and 52% and the 2nd phase by 37, 50, and 67%, at the doses of 1, 5, and 10 mg/kg, respectively. …”

DataSheet1_Amygdalin as a chemoprotective agent in co-treatment with cisplatin.PDF by Panayiota Christodoulou (13832038)

“…As attested by flow cytometry, combination treatment was associated with decreased the percentage of late apoptotic cells compared with monotherapy (fold-change of decrease = 1.6 and 4.5 for 15 and 20 μΜ, respectively). …”

Life span assay for <i>C</i>. <i>elegans</i> infected with STEC strains compared to that for <i>C</i>. <i>elegans</i> infected with the control <i>E</i>. <i>coli</i> OP50 strain. by Su-Bin Hwang (4898887)

“…<i>elegans</i> grown on the E5 and E6 strains. <i>C</i>. <i>elegans</i> grown on both E5 and E6 exhibited a decreased life span at the end of 10 days, but <i>C</i>. …”

Curve fitting of UCS. by Gaojian Hu (11457537)

“…The research results indicate that: (1) the uniaxial compressive strength decreases with the increase of the rock bridge angle, showing a power function relationship; (2) The uniaxial compressive strength decreases with the increase of rock size and tends to stabilize when the rock size is greater than 350 mm, showing a significant size effect. (3) The fluctuation coefficient of compressive strength increases with the increase of rock bridge angle and decreases with the increase of rock size; When the rock size is 350 mm, the fluctuation coefficient is less than 5%; (4) The characteristic compressive strength and characteristic size both increase with the increase of the rock bridge angle.…”

Fluctuation coefficient of UCS. by Gaojian Hu (11457537)

“…The research results indicate that: (1) the uniaxial compressive strength decreases with the increase of the rock bridge angle, showing a power function relationship; (2) The uniaxial compressive strength decreases with the increase of rock size and tends to stabilize when the rock size is greater than 350 mm, showing a significant size effect. (3) The fluctuation coefficient of compressive strength increases with the increase of rock bridge angle and decreases with the increase of rock size; When the rock size is 350 mm, the fluctuation coefficient is less than 5%; (4) The characteristic compressive strength and characteristic size both increase with the increase of the rock bridge angle.…”

Numerical simulation model. by Gaojian Hu (11457537)

“…The research results indicate that: (1) the uniaxial compressive strength decreases with the increase of the rock bridge angle, showing a power function relationship; (2) The uniaxial compressive strength decreases with the increase of rock size and tends to stabilize when the rock size is greater than 350 mm, showing a significant size effect. (3) The fluctuation coefficient of compressive strength increases with the increase of rock bridge angle and decreases with the increase of rock size; When the rock size is 350 mm, the fluctuation coefficient is less than 5%; (4) The characteristic compressive strength and characteristic size both increase with the increase of the rock bridge angle.…”

Mechanical parameters. by Gaojian Hu (11457537)

“…The research results indicate that: (1) the uniaxial compressive strength decreases with the increase of the rock bridge angle, showing a power function relationship; (2) The uniaxial compressive strength decreases with the increase of rock size and tends to stabilize when the rock size is greater than 350 mm, showing a significant size effect. (3) The fluctuation coefficient of compressive strength increases with the increase of rock bridge angle and decreases with the increase of rock size; When the rock size is 350 mm, the fluctuation coefficient is less than 5%; (4) The characteristic compressive strength and characteristic size both increase with the increase of the rock bridge angle.…”

Fig 2 - by Pedro F. S. Freitas (10331819)

Fitting relationship between rock size and UCS. by Gaojian Hu (11457537)

“…The research results indicate that: (1) the uniaxial compressive strength decreases with the increase of the rock bridge angle, showing a power function relationship; (2) The uniaxial compressive strength decreases with the increase of rock size and tends to stabilize when the rock size is greater than 350 mm, showing a significant size effect. (3) The fluctuation coefficient of compressive strength increases with the increase of rock bridge angle and decreases with the increase of rock size; When the rock size is 350 mm, the fluctuation coefficient is less than 5%; (4) The characteristic compressive strength and characteristic size both increase with the increase of the rock bridge angle.…”