Adipose-derived stem cells attenuate pulmonary microvascular hyperpermeability after smoke inhalation by Koji Ihara (4495504)

“…Sheep were randomly allocated to two groups: 1) ASCs: infused with 200 million of ASCs in 200mL of PlasmaLyteA starting 1 hours post-injury, n = 5; 2) control, treated with 200mL of PlasmaLyteA in a similar pattern, n = 5.…”

<i>Lhfp</i> is a negative regulator of osteoblast differentiation and cortical bone mass. by Larry D. Mesner (553519)

“…<p>A) <i>Lhfp</i> transcript levels are decreased due to the five nonsense mutations created using CRISPR/Cas9 (<i>Lhfp</i>^<i>+/+</i>, N = 10; <i>Lhfp</i>^<i>+/-</i>, N = 11; <i>Lhfp</i>^<i>-/-</i>, N = 7; represents at least one mouse from each of the five mutant lines, see <b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008123#pgen.1008123.t001" target="_blank">Table 1</a></b>). …”

Table_1_Daily Intake of a Phaseolus vulgaris L. Snack Bar Attenuates Hypertriglyceridemia and Improves Lipid Metabolism-Associated Plasma Proteins in Mexican Women: A Randomized Cl... by Aurea K. Ramírez-Jiménez (12750107)

“…A modest body weight (5%) reduction was also found. …”

Gene expression profiles of DKK1, CYR61, CTGF, TGFBR1, COL3A1, COL1A1, ITGA2, MMP14, MMP2, TIMP2, TIMP1, TIMP3. by Hermann Agis (660951)

“…Data points represent 5 samples</p>…”

Supplementary Material for: Trends in the Incidence of Rare Eyelid Malignancies: A SEER-Based Study (2000–2021) by figshare admin karger (2628495)

Genetic Polymorphisms in XRCC1, CD3EAP, PPP1R13L, XPB, XPC, and XPF and the Risk of Chronic Benzene Poisoning in a Chinese Occupational Population by Ping Xue (167911)

“…However, the T allele in PPP1R13L rs1005165 (P<0.05) and the GA allele in CD3EAP rs967591 (OR = 0.162; 95% CI: 0039~0.666; <i>P</i> = 0.037) decreased the risk of CBP in men. The haplotype analysis of XRCC1 indicated that XRCC1 rs25487^A, rs25489^G and rs1799782^T (OR = 15.469; 95% CI: 5.536–43.225; <i>P</i><0.001) were associated with a high risk of CBP.…”

Inactivation of <i>Salmonella</i> Typhimurium and <i>Listeria monocytogenes</i> on ham with nonthermal atmospheric pressure plasma by Karolina Anna Lis (5278934)

“…The chosen plasma modes had a peak-to-peak voltage of 6.4 or 10 kV and a frequency of 2 and 10 kHz. …”

Efficacy and safety of saxagliptin in combination with insulin in Japanese patients with type 2 diabetes mellitus: a 16-week double-blind randomized controlled trial with a 36-week... by Takashi Kadowaki (35402)

“…</p> <p><b>Research design and methods</b>: We randomized 240 patients with type 2 diabetes mellitus on insulin monotherapy to 5-mg saxagliptin or placebo as add-on therapy for a 16-week, double-blind period. …”

Combination treatment of berberine and solid lipid curcumin particles increased cell death and inhibited PI3K/Akt/mTOR pathway of human cultured glioblastoma cells more effectively... by Panchanan Maiti (1459852)

“…Due to the poor solubility and limited bioavailability, these compounds have limited efficacy for treating cancer. However, use of a formulation of curcumin with higher bioavailability or combining it with berberine as a co-treatment may be proving to be more efficacious against cancer. …”

Alexia Searchfield: Born Too Small? Is this a risk factor for low educational attainment? by Alexia Kate Searchfield (4080514)

Reduced RNA expression of the <i>FMR1</i> gene in women with low (CGG_n<26) repeats by Qi Wang (22418)

“…The main outcome measure was RNA expression in human luteinized granulosa cells of 5 groups of FMRP isoforms. The relative expression of FMR1 RNA in human luteinized granulosa cells was measured by real-time PCR and a possible association with CGG_n was explored. …”

Predicted performance of a control program administered to dogs on arrival in US animal shelters. by Benjamin D. Dalziel (650353)

“…(<b>B</b>) Decreasing control efficacy to 75% can still achieve eradication in isolated shelters (blue region, solid line), however shelters that transfer dogs amongst themselves at the observed mean rate of τ = 0.1 would preserve CIV in a few shelters despite the vaccination program (red region, dashed line). …”

Optimal Dose and Method of Administration of Intravenous Insulin in the Management of Emergency Hyperkalemia: A Systematic Review by Ziv Harel (2696983)

“…There was no statistically significant difference in mean decrease in serum potassium (K⁺) concentration at 60 minutes between studies in which insulin was administered as an infusion of 20 units over 60 minutes and studies in which 10 units of insulin was administered as a bolus (0.79±0.25 mmol/L versus 0.78±0.25 mmol/L, <i>P</i> = 0.98) or studies in which 10 units of insulin was administered as an infusion (0.79±0.25 mmol/L versus 0.39±0.09 mmol/L, <i>P</i> = 0.1). …”

An idealized view of the opportunity provided by a comparative and integrated oncology drug development path. by Ira Gordon (369869)

“…Factoring in additional costs for comparative studies with this approach of US$150,000 for studies conducted in the preclinical setting, US$250,000 for studies conducted before or during Phases I–II human trials and US$1 million for studies conducted before Phases II–III studies, the total cost of development is estimated at US$2.07 billion. The result may be a decrease in average clinical trial costs per approved drug from US$290 million to US$173 million <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1000161#pmed.1000161-Adams1" target="_blank">[5]</a>.…”

The changing trends of <i>f</i>_<i>i</i>, <i>i</i> ∈ {1, 2, 3, 4} with <i>v</i> for the Moran process (first row) and the Wright-Fisher process (second row) when <i>u</i>... by Yanling Zhang (6561)

“…For all <i>r</i>, The curve of <i>f</i>₄ with <i>v</i> (fourth column) has an increasing trend with a small perturbation near <i>v</i> = 0.01. …”

Data_Sheet_1_Expression of vitamin D receptor, CYP24A1, and CYP27B1 in normal and inflamed canine pancreases.DOCX by Dohee Lee (432106)

“…This study showed that VDR expression decreased in inflamed pancreases and demonstrated CYP24A1 and CYP27B1 expression in the canine pancreas for the first time. …”

Core–Shell {Mn₇⊂(Mn,Cd)₁₂} Assembled from Core {Mn₇} Disc by Ling-Yu Guo (3068232)

“…HR-ESI-MS was even more precise by revealing three prominent molecular species, Mn₁₃Cd₆, Mn₁₄Cd₅ and Mn₁₅Cd₄, having a distribution of metals. …”

Temperature-Induced Phase Transitions of Vivianite: In Situ Analysis of a Redox-Driven Crystallization by Alice Paskin (10017280)

Diabetes, Drug Treatment and Mortality in COVID-19: A Multinational Retrospective Cohort Study by Jennifer E. Nyland (11412878)

“…Use of DPP-4 inhibitors was associated with a reduction in respiratory complications (24.0% vs 29.2%; RR, 0.82 [95% CI, 0.74-0.90]; <i>P</i> <.001), and continued use of DPP-4 inhibitors after hospitalization was associated with a decrease in mortality compared with those who discontinued use (9% vs 19%; RR, 0.45 [95% CI, 0.28-0.72]; <i>P</i> <.001). …”

Application of product development tools in equipment design for a technology-based small business by Felipe Mello Pierobom (10396580)